Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KRT73 (keratin 73, type II)

Identity

Alias_nameskeratin 73, type II
Alias_symbol (synonym)KRT6IRS3
K6IRS3
Other aliasIRT6IRS3
HGNC (Hugo) KRT73
LocusID (NCBI) 319101
Atlas_Id 65037
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 53001354 and ends at 53012343 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KRT73   28928
Cards
Entrez_Gene (NCBI)KRT73  319101  keratin 73, type II
AliasesIRT6IRS3; K6IRS3; KRT6IRS3
GeneCards (Weizmann)KRT73
Ensembl hg19 (Hinxton)ENSG00000186049 [Gene_View]  chr12:53001354-53012343 [Contig_View]  KRT73 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186049 [Gene_View]  chr12:53001354-53012343 [Contig_View]  KRT73 [Vega]
ICGC DataPortalENSG00000186049
TCGA cBioPortalKRT73
AceView (NCBI)KRT73
Genatlas (Paris)KRT73
WikiGenes319101
SOURCE (Princeton)KRT73
Genetics Home Reference (NIH)KRT73
Genomic and cartography
GoldenPath hg19 (UCSC)KRT73  -     chr12:53001354-53012343 -  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KRT73  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblKRT73 - 12q13.13 [CytoView hg19]  KRT73 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIKRT73 [Mapview hg19]  KRT73 [Mapview hg38]
OMIM608247   
Gene and transcription
Genbank (Entrez)AJ508776 BC109212
RefSeq transcript (Entrez)NM_175068
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_012319 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)KRT73
Cluster EST : UnigeneHs.55410 [ NCBI ]
CGAP (NCI)Hs.55410
Alternative Splicing GalleryENSG00000186049
Gene ExpressionKRT73 [ NCBI-GEO ]   KRT73 [ EBI - ARRAY_EXPRESS ]   KRT73 [ SEEK ]   KRT73 [ MEM ]
Gene Expression Viewer (FireBrowse)KRT73 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)319101
GTEX Portal (Tissue expression)KRT73
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86Y46   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86Y46  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86Y46
Splice isoforms : SwissVarQ86Y46
PhosPhoSitePlusQ86Y46
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_II   
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
Conserved Domain (NCBI)KRT73
DMDM Disease mutations319101
Blocks (Seattle)KRT73
SuperfamilyQ86Y46
Human Protein AtlasENSG00000186049
Peptide AtlasQ86Y46
HPRD16304
IPIIPI00174775   IPI00878987   IPI01022184   
Protein Interaction databases
DIP (DOE-UCLA)Q86Y46
IntAct (EBI)Q86Y46
FunCoupENSG00000186049
BioGRIDKRT73
STRING (EMBL)KRT73
ZODIACKRT73
Ontologies - Pathways
QuickGOQ86Y46
Ontology : AmiGOmolecular_function  structural molecule activity  protein binding  nucleus  biological_process  keratin filament  extracellular exosome  activation of mitophagy in response to mitochondrial depolarization  
Ontology : EGO-EBImolecular_function  structural molecule activity  protein binding  nucleus  biological_process  keratin filament  extracellular exosome  activation of mitophagy in response to mitochondrial depolarization  
NDEx NetworkKRT73
Atlas of Cancer Signalling NetworkKRT73
Wikipedia pathwaysKRT73
Orthology - Evolution
OrthoDB319101
GeneTree (enSembl)ENSG00000186049
Phylogenetic Trees/Animal Genes : TreeFamKRT73
HOVERGENQ86Y46
HOGENOMQ86Y46
Homologs : HomoloGeneKRT73
Homology/Alignments : Family Browser (UCSC)KRT73
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKRT73 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT73
dbVarKRT73
ClinVarKRT73
1000_GenomesKRT73 
Exome Variant ServerKRT73
ExAC (Exome Aggregation Consortium)KRT73 (select the gene name)
Genetic variants : HAPMAP319101
Genomic Variants (DGV)KRT73 [DGVbeta]
DECIPHER (Syndromes)12:53001354-53012343  ENSG00000186049
CONAN: Copy Number AnalysisKRT73 
Mutations
ICGC Data PortalKRT73 
TCGA Data PortalKRT73 
Broad Tumor PortalKRT73
OASIS PortalKRT73 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT73  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKRT73
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KRT73
DgiDB (Drug Gene Interaction Database)KRT73
DoCM (Curated mutations)KRT73 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KRT73 (select a term)
intoGenKRT73
Cancer3DKRT73(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608247   
Orphanet
MedgenKRT73
Genetic Testing Registry KRT73
NextProtQ86Y46 [Medical]
TSGene319101
GENETestsKRT73
Huge Navigator KRT73 [HugePedia]
snp3D : Map Gene to Disease319101
BioCentury BCIQKRT73
ClinGenKRT73
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD319101
Chemical/Pharm GKB GenePA147031702
Clinical trialKRT73
Miscellaneous
canSAR (ICR)KRT73 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKRT73
EVEXKRT73
GoPubMedKRT73
iHOPKRT73
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:10:16 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.