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KRT78 (keratin 78)

Identity

Alias (NCBI)CK-78
K5B
K78
Kb40
HGNC (Hugo) KRT78
HGNC Alias symbK5B
HGNC Previous namekeratin 78, type II
LocusID (NCBI) 196374
Atlas_Id 65042
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 52837810 and ends at 52848994 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NRG1 (8p12)::KRT78 (12q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KRT78   28926
Cards
Entrez_Gene (NCBI)KRT78    keratin 78
AliasesCK-78; K5B; K78; Kb40
GeneCards (Weizmann)KRT78
Ensembl hg19 (Hinxton)ENSG00000170423 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170423 [Gene_View]  ENSG00000170423 [Sequence]  chr12:52837810-52848994 [Contig_View]  KRT78 [Vega]
ICGC DataPortalENSG00000170423
TCGA cBioPortalKRT78
AceView (NCBI)KRT78
Genatlas (Paris)KRT78
SOURCE (Princeton)KRT78
Genetics Home Reference (NIH)KRT78
Genomic and cartography
GoldenPath hg38 (UCSC)KRT78  -     chr12:52837810-52848994 -  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KRT78  -     12q13.13   [Description]    (hg19-Feb_2009)
GoldenPathKRT78 - 12q13.13 [CytoView hg19]  KRT78 - 12q13.13 [CytoView hg38]
ImmunoBaseENSG00000170423
Genome Data Viewer NCBIKRT78 [Mapview hg19]  
OMIM611159   
Gene and transcription
Genbank (Entrez)AI143912 AK096419 AK290901 AK298636 BX647095
RefSeq transcript (Entrez)NM_001300814 NM_173352
Consensus coding sequences : CCDS (NCBI)KRT78
Gene ExpressionKRT78 [ NCBI-GEO ]   KRT78 [ EBI - ARRAY_EXPRESS ]   KRT78 [ SEEK ]   KRT78 [ MEM ]
Gene Expression Viewer (FireBrowse)KRT78 [ Firebrowse - Broad ]
GenevisibleExpression of KRT78 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)196374
GTEX Portal (Tissue expression)KRT78
Human Protein AtlasENSG00000170423-KRT78 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N1N4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N1N4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N1N4
PhosPhoSitePlusQ8N1N4
Domaine pattern : Prosite (Expaxy)IF_ROD_1 (PS00226)    IF_ROD_2 (PS51842)   
Domains : Interpro (EBI)IF_conserved    IF_rod_dom    IF_rod_dom_coil1B    Keratin_2_head    Keratin_II   
Domain families : Pfam (Sanger)Filament (PF00038)    Keratin_2_head (PF16208)   
Domain families : Pfam (NCBI)pfam00038    pfam16208   
Domain families : Smart (EMBL)Filament (SM01391)  
Conserved Domain (NCBI)KRT78
SuperfamilyQ8N1N4
AlphaFold pdb e-kbQ8N1N4   
Human Protein Atlas [tissue]ENSG00000170423-KRT78 [tissue]
HPRD17171
Protein Interaction databases
DIP (DOE-UCLA)Q8N1N4
IntAct (EBI)Q8N1N4
BioGRIDKRT78
STRING (EMBL)KRT78
ZODIACKRT78
Ontologies - Pathways
QuickGOQ8N1N4
Ontology : AmiGOprotein binding  extracellular space  cytosol  keratinization  keratin filament  extracellular exosome  cornification  
Ontology : EGO-EBIprotein binding  extracellular space  cytosol  keratinization  keratin filament  extracellular exosome  cornification  
NDEx NetworkKRT78
Atlas of Cancer Signalling NetworkKRT78
Wikipedia pathwaysKRT78
Orthology - Evolution
OrthoDB196374
GeneTree (enSembl)ENSG00000170423
Phylogenetic Trees/Animal Genes : TreeFamKRT78
Homologs : HomoloGeneKRT78
Homology/Alignments : Family Browser (UCSC)KRT78
Gene fusions - Rearrangements
Fusion : QuiverKRT78
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKRT78 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT78
dbVarKRT78
ClinVarKRT78
MonarchKRT78
1000_GenomesKRT78 
Exome Variant ServerKRT78
GNOMAD BrowserENSG00000170423
Varsome BrowserKRT78
ACMGKRT78 variants
VarityQ8N1N4
Genomic Variants (DGV)KRT78 [DGVbeta]
DECIPHERKRT78 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKRT78 
Mutations
ICGC Data PortalKRT78 
TCGA Data PortalKRT78 
Broad Tumor PortalKRT78
OASIS PortalKRT78 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT78  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKRT78
Mutations and Diseases : HGMDKRT78
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKRT78
DgiDB (Drug Gene Interaction Database)KRT78
DoCM (Curated mutations)KRT78
CIViC (Clinical Interpretations of Variants in Cancer)KRT78
Cancer3DKRT78
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611159   
Orphanet
DisGeNETKRT78
MedgenKRT78
Genetic Testing Registry KRT78
NextProtQ8N1N4 [Medical]
GENETestsKRT78
Target ValidationKRT78
Huge Navigator KRT78 [HugePedia]
ClinGenKRT78
Clinical trials, drugs, therapy
MyCancerGenomeKRT78
Protein Interactions : CTDKRT78
Pharm GKB GenePA147357807
PharosQ8N1N4
Clinical trialKRT78
Miscellaneous
canSAR (ICR)KRT78
HarmonizomeKRT78
ARCHS4KRT78
DataMed IndexKRT78
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKRT78
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sun Jan 16 18:57:51 CET 2022

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