KSR2 (kinase suppressor of ras 2)

Identity

Other names	FLJ25965
HGNC	KSR2
Location	12q24.22-q24.23
Location_base_pair	Starts at 116375200 and ends at 116890411 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	KSR2   18610
Entrez_Gene	KSR2  283455  kinase suppressor of ras 2
	Cards
GeneCards	KSR2
Ensembl	KSR2 [Search_View]   ENSG00000204820 [Gene_View]
Genatlas	KSR2
GeneLynx	KSR2
eGenome	KSR2
euGene	283455
	Genomic and cartography
GoldenPath	KSR2  -     chr12:116375200-116890411 -  12q24.22   [Description]    (hg18-March_2006)
Ensembl	KSR2 - 12q24.22 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	KSR2
	Gene and transcription
Genbank	AK098831 [ ENTREZ ]
Genbank	AY345972 [ ENTREZ ]
Genbank	BC107106 [ ENTREZ ]
Genbank	BC107107 [ ENTREZ ]
Genbank	BC127603 [ ENTREZ ]
RefSeq	NM_173598 [ SRS ]    NM_173598 [ ENTREZ ]
RefSeq	AC_000055 [ SRS ]    AC_000055 [ ENTREZ ]
RefSeq	AC_000144 [ SRS ]    AC_000144 [ ENTREZ ]
RefSeq	NC_000012 [ SRS ]    NC_000012 [ ENTREZ ]
RefSeq	NT_009775 [ SRS ]    NT_009775 [ ENTREZ ]
RefSeq	NW_001838063 [ SRS ]    NW_001838063 [ ENTREZ ]
RefSeq	NW_925395 [ SRS ]    NW_925395 [ ENTREZ ]
AceView	KSR2 AceView - NCBI
Unigene	Hs.375836 [ SRS ]    Hs.375836 [ NCBI ]     HS375836 [ spliceNest ]
Fast-db	13915 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q6VAB6 [ SRS]    Q6VAB6 [ EXPASY ]     Q6VAB6 [ INTERPRO ]     Q6VAB6 [ UNIPROT ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Prosite	PS00479 ZF_DAG_PE_1 [ SRS ]    PS00479 ZF_DAG_PE_1 [ Expasy ]
Prosite	PS50081 ZF_DAG_PE_2 [ SRS ]    PS50081 ZF_DAG_PE_2 [ Expasy ]
Interpro	IPR002219 DAG_PE_bd [ SRS ]    IPR002219 DAG_PE_bd [ EBI ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
CluSTr	Q6VAB6
Pfam	PF00130 C1_1 [ SRS ]    PF00130 C1_1 [ Sanger ]    pfam00130 [ NCBI-CDD ]
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00109 C1 [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q6VAB6 KSR2_HUMAN [ Domain structure ]   Q6VAB6 KSR2_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q6VAB6
HPRD	13952
	Protein Interaction databases
DIP	Q6VAB6
IntAct	Q6VAB6
	Polymorphism : SNP, mutations, diseases
OMIM	610737    [ map ]
GENECLINICS	610737
SNP	KSR2 [dbSNP-NCBI]
SNP	NM_173598 [SNP-NCI]
SNP	KSR2 [GeneSNPs - Utah]  KSR2] [HGBASE - SRS]
HAPMAP	KSR2 [HAPMAP]
COSMIC	KSR2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	KSR2
	General knowledge
Family Browser	KSR2 [UCSC Family Browser]
SOURCE	NM_173598
SMD	Hs.375836
SAGE	Hs.375836
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	zinc ion binding [Amigo]  zinc ion binding
GO	membrane [Amigo]  membrane
GO	diacylglycerol binding [Amigo]  diacylglycerol binding
GO	metal ion binding [Amigo]  metal ion binding
PubGene	KSR2
TreeFam	KSR2
CTD	283455 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	KSR2 Related clones (RZPD - Berlin)
	PubMed
PubMed	7 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:48:10 2008