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L3HYPDH (trans-L-3-hydroxyproline dehydratase)

Identity

Alias_namesC14orf149
chromosome 14 open reading frame 149
L-3-hydroxyproline dehydratase (trans-)
Alias_symbol (synonym)FLJ25436
Other alias
HGNC (Hugo) L3HYPDH
LocusID (NCBI) 112849
Atlas_Id 65152
Location 14q23.1  [Link to chromosome band 14q23]
Location_base_pair Starts at 59472688 and ends at 59484355 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARID4A (14q23.1) / L3HYPDH (14q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)L3HYPDH   20488
Cards
Entrez_Gene (NCBI)L3HYPDH  112849  trans-L-3-hydroxyproline dehydratase
AliasesC14orf149
GeneCards (Weizmann)L3HYPDH
Ensembl hg19 (Hinxton)ENSG00000126790 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126790 [Gene_View]  chr14:59472688-59484355 [Contig_View]  L3HYPDH [Vega]
ICGC DataPortalENSG00000126790
TCGA cBioPortalL3HYPDH
AceView (NCBI)L3HYPDH
Genatlas (Paris)L3HYPDH
WikiGenes112849
SOURCE (Princeton)L3HYPDH
Genetics Home Reference (NIH)L3HYPDH
Genomic and cartography
GoldenPath hg38 (UCSC)L3HYPDH  -     chr14:59472688-59484355 -  14q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)L3HYPDH  -     14q23.1   [Description]    (hg19-Feb_2009)
EnsemblL3HYPDH - 14q23.1 [CytoView hg19]  L3HYPDH - 14q23.1 [CytoView hg38]
Mapping of homologs : NCBIL3HYPDH [Mapview hg19]  L3HYPDH [Mapview hg38]
OMIM614811   
Gene and transcription
Genbank (Entrez)AA483488 AK058165 AK294843 BC012131
RefSeq transcript (Entrez)NM_001331158 NM_001331159 NM_001331164 NM_144581
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)L3HYPDH
Cluster EST : UnigeneHs.729061 [ NCBI ]
CGAP (NCI)Hs.729061
Alternative Splicing GalleryENSG00000126790
Gene ExpressionL3HYPDH [ NCBI-GEO ]   L3HYPDH [ EBI - ARRAY_EXPRESS ]   L3HYPDH [ SEEK ]   L3HYPDH [ MEM ]
Gene Expression Viewer (FireBrowse)L3HYPDH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)112849
GTEX Portal (Tissue expression)L3HYPDH
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96EM0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96EM0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96EM0
Splice isoforms : SwissVarQ96EM0
PhosPhoSitePlusQ96EM0
Domains : Interpro (EBI)Pro_racemase_fam   
Domain families : Pfam (Sanger)Pro_racemase (PF05544)   
Domain families : Pfam (NCBI)pfam05544   
Conserved Domain (NCBI)L3HYPDH
DMDM Disease mutations112849
Blocks (Seattle)L3HYPDH
SuperfamilyQ96EM0
Human Protein AtlasENSG00000126790
Peptide AtlasQ96EM0
HPRD08065
IPIIPI00386591   IPI00966435   IPI00985416   
Protein Interaction databases
DIP (DOE-UCLA)Q96EM0
IntAct (EBI)Q96EM0
FunCoupENSG00000126790
BioGRIDL3HYPDH
STRING (EMBL)L3HYPDH
ZODIACL3HYPDH
Ontologies - Pathways
QuickGOQ96EM0
Ontology : AmiGOmetabolic process  hydro-lyase activity  proline racemase activity  trans-L-3-hydroxyproline dehydratase activity  
Ontology : EGO-EBImetabolic process  hydro-lyase activity  proline racemase activity  trans-L-3-hydroxyproline dehydratase activity  
NDEx NetworkL3HYPDH
Atlas of Cancer Signalling NetworkL3HYPDH
Wikipedia pathwaysL3HYPDH
Orthology - Evolution
OrthoDB112849
GeneTree (enSembl)ENSG00000126790
Phylogenetic Trees/Animal Genes : TreeFamL3HYPDH
HOVERGENQ96EM0
HOGENOMQ96EM0
Homologs : HomoloGeneL3HYPDH
Homology/Alignments : Family Browser (UCSC)L3HYPDH
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerL3HYPDH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)L3HYPDH
dbVarL3HYPDH
ClinVarL3HYPDH
1000_GenomesL3HYPDH 
Exome Variant ServerL3HYPDH
ExAC (Exome Aggregation Consortium)L3HYPDH (select the gene name)
Genetic variants : HAPMAP112849
Genomic Variants (DGV)L3HYPDH [DGVbeta]
DECIPHERL3HYPDH [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisL3HYPDH 
Mutations
ICGC Data PortalL3HYPDH 
TCGA Data PortalL3HYPDH 
Broad Tumor PortalL3HYPDH
OASIS PortalL3HYPDH [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDL3HYPDH
BioMutasearch L3HYPDH
DgiDB (Drug Gene Interaction Database)L3HYPDH
DoCM (Curated mutations)L3HYPDH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)L3HYPDH (select a term)
intoGenL3HYPDH
Cancer3DL3HYPDH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614811   
Orphanet
MedgenL3HYPDH
Genetic Testing Registry L3HYPDH
NextProtQ96EM0 [Medical]
TSGene112849
GENETestsL3HYPDH
Target ValidationL3HYPDH
Huge Navigator L3HYPDH [HugePedia]
snp3D : Map Gene to Disease112849
BioCentury BCIQL3HYPDH
ClinGenL3HYPDH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD112849
Chemical/Pharm GKB GenePA134961537
Clinical trialL3HYPDH
Miscellaneous
canSAR (ICR)L3HYPDH (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineL3HYPDH
EVEXL3HYPDH
GoPubMedL3HYPDH
iHOPL3HYPDH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:12:28 CEST 2017

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