Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

L3MBTL1 (l(3)mbt-like 1 (Drosophila))

Identity

Alias_namesL3MBTL
l(3)mbt (Drosophila)-like
l(3)mbt-like (Drosophila)
Alias_symbol (synonym)ZC2HC3
dJ138B7.3
DKFZp586P1522
KIAA0681
Other aliasH-L(3)MBT
HGNC (Hugo) L3MBTL1
LocusID (NCBI) 26013
Atlas_Id 51666
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 43514436 and ends at 43541895 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
L3MBTL1 (20q13.12) / L3MBTL1 (20q13.12)SH3GL3 (15q25.2) / L3MBTL1 (20q13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

<ÔR>8TD WIDTH=15%>Domains : Interpro (EBI)
Nomenclature
HGNC (Hugo)L3MBTL1   15905
LRG (Locus Reference Genomic)LRG_1049
Cards
Entrez_Gene (NCBI)L3MBTL1  26013  l(3)mbt-like 1 (Drosophila)
AliasesH-L(3)MBT; L3MBTL; ZC2HC3; dJ138B7.3
GeneCards (Weizmann)L3MBTL1
Ensembl hg19 (Hinxton)ENSG00000185513 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185513 [Gene_View]  chr20:43514436-43541895 [Contig_View]  L3MBTL1 [Vega]
ICGC DataPortalENSG00000185513
TCGA cBioPortalL3MBTL1
AceView (NCBI)L3MBTL1
Genatlas (Paris)L3MBTL1
WikiGenes26013
SOURCE (Princeton)L3MBTL1
Genetics Home Reference (NIH)L3MBTL1
Genomic and cartography
GoldenPath hg38 (UCSC)L3MBTL1  -     chr20:43514436-43541895 +  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)L3MBTL1  -     20q13.12   [Description]    (hg19-Feb_2009)
EnsemblL3MBTL1 - 20q13.12 [CytoView hg19]  L3MBTL1 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBIL3MBTL1 [Mapview hg19]  L3MBTL1 [Mapview hg38]
OMIM608802   
Gene and transcription
Genbank (Entrez)AB014581 AK123176 AK299199 AK308334 AK310345
RefSeq transcript (Entrez)NM_015478 NM_032107
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)L3MBTL1
Cluster EST : UnigeneHs.736988 [ NCBI ]
CGAP (NCI)Hs.736988
Alternative Splicing GalleryENSG00000185513
Gene ExpressionL3MBTL1 [ NCBI-GEO ]   L3MBTL1 [ EBI - ARRAY_EXPRESS ]   L3MBTL1 [ SEEK ]   L3MBTL1 [ MEM ]
Gene Expression Viewer (FireBrowse)L3MBTL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26013
GTEX Portal (Tissue expression)L3MBTL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y468   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y468  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y468
Splice isoforms : SwissVarQ9Y468
PhosPhoSitePlusQ9Y468
Domaine pattern : Prosite (Expaxy)MBT (PS51079)    SAM_DOMAIN (PS50105)    ZF_CCHHC (PS51802)   
Mbt    SAM    SAM/pointed    Znf_C2HC   
Domain families : Pfam (Sanger)MBT (PF02820)    SAM_1 (PF00536)    zf-C2HC (PF01530)   
Domain families : Pfam (NCBI)pfam02820    pfam00536    pfam01530   
Domain families : Smart (EMBL)MBT (SM00561)  SAM (SM00454)  
Conserved Domain (NCBI)L3MBTL1
DMDM Disease mutations26013
Blocks (Seattle)L3MBTL1
PDB (SRS)1OYX    1OZ2    1OZ3    2PQW    2RHI    2RHU    2RHX    2RHY    2RHZ    2RI2    2RI3    2RI5    2RJC    2RJD    2RJE    2RJF    3OQ5    3P8H    3UWN   
PDB (PDBSum)1OYX    1OZ2    1OZ3    2PQW    2RHI    2RHU    2RHX    2RHY    2RHZ    2RI2    2RI3    2RI5    2RJC    2RJD    2RJE    2RJF    3OQ5    3P8H    3UWN   
PDB (IMB)1OYX    1OZ2    1OZ3    2PQW    2RHI    2RHU    2RHX    2RHY    2RHZ    2RI2    2RI3    2RI5    2RJC    2RJD    2RJE    2RJF    3OQ5    3P8H    3UWN   
PDB (RSDB)1OYX    1OZ2    1OZ3    2PQW    2RHI    2RHU    2RHX    2RHY    2RHZ    2RI2    2RI3    2RI5    2RJC    2RJD    2RJE    2RJF    3OQ5    3P8H    3UWN   
Structural Biology KnowledgeBase1OYX    1OZ2    1OZ3    2PQW    2RHI    2RHU    2RHX    2RHY    2RHZ    2RI2    2RI3    2RI5    2RJC    2RJD    2RJE    2RJF    3OQ5    3P8H    3UWN   
SCOP (Structural Classification of Proteins)1OYX    1OZ2    1OZ3    2PQW    2RHI    2RHU    2RHX    2RHY    2RHZ    2RI2    2RI3    2RI5    2RJC    2RJD    2RJE    2RJF    3OQ5    3P8H    3UWN   
CATH (Classification of proteins structures)1OYX    1OZ2    1OZ3    2PQW    2RHI    2RHU    2RHX    2RHY    2RHZ    2RI2    2RI3    2RI5    2RJC    2RJD    2RJE    2RJF    3OQ5    3P8H    3UWN   
SuperfamilyQ9Y468
Human Protein AtlasENSG00000185513
Peptide AtlasQ9Y468
HPRD16387
IPIIPI00879524   IPI00333371   IPI00216288   IPI00216289   IPI00971010   IPI00879376   IPI00446752   IPI00979655   IPI00552042   IPI01017904   IPI00879827   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y468
IntAct (EBI)Q9Y468
FunCoupENSG00000185513
BioGRIDL3MBTL1
STRING (EMBL)L3MBTL1
ZODIACL3MBTL1
Ontologies - Pathways
QuickGOQ9Y468
Ontology : AmiGOchromatin  condensed chromosome  chromatin binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  plasma membrane  chromatin organization  transcription, DNA-templated  regulation of mitotic nuclear division  zinc ion binding  covalent chromatin modification  hemopoiesis  nucleosome binding  nucleosomal histone binding  SAM domain binding  methylated histone binding  methylated histone binding  histone binding  identical protein binding  regulation of megakaryocyte differentiation  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  regulation of cell cycle  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIchromatin  condensed chromosome  chromatin binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  plasma membrane  chromatin organization  transcription, DNA-templated  regulation of mitotic nuclear division  zinc ion binding  covalent chromatin modification  hemopoiesis  nucleosome binding  nucleosomal histone binding  SAM domain binding  methylated histone binding  methylated histone binding  histone binding  identical protein binding  regulation of megakaryocyte differentiation  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  regulation of cell cycle  regulation of signal transduction by p53 class mediator  
NDEx NetworkL3MBTL1
Atlas of Cancer Signalling NetworkL3MBTL1
Wikipedia pathwaysL3MBTL1
Orthology - Evolution
OrthoDB26013
GeneTree (enSembl)ENSG00000185513
Phylogenetic Trees/Animal Genes : TreeFamL3MBTL1
HOVERGENQ9Y468
HOGENOMQ9Y468
Homologs : HomoloGeneL3MBTL1
Homology/Alignments : Family Browser (UCSC)L3MBTL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerL3MBTL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)L3MBTL1
dbVarL3MBTL1
ClinVarL3MBTL1
1000_GenomesL3MBTL1 
Exome Variant ServerL3MBTL1
ExAC (Exome Aggregation Consortium)L3MBTL1 (select the gene name)
Genetic variants : HAPMAP26013
Genomic Variants (DGV)L3MBTL1 [DGVbeta]
DECIPHERL3MBTL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisL3MBTL1 
Mutations
ICGC Data PortalL3MBTL1 
TCGA Data PortalL3MBTL1 
Broad Tumor PortalL3MBTL1
OASIS PortalL3MBTL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICL3MBTL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDL3MBTL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch L3MBTL1
DgiDB (Drug Gene Interaction Database)L3MBTL1
DoCM (Curated mutations)L3MBTL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)L3MBTL1 (select a term)
intoGenL3MBTL1
Cancer3DL3MBTL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608802   
Orphanet
MedgenL3MBTL1
Genetic Testing Registry L3MBTL1
NextProtQ9Y468 [Medical]
TSGene26013
GENETestsL3MBTL1
Target ValidationL3MBTL1
Huge Navigator L3MBTL1 [HugePedia]
snp3D : Map Gene to Disease26013
BioCentury BCIQL3MBTL1
ClinGenL3MBTL1 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26013
Chemical/Pharm GKB GenePA30260
Clinical trialL3MBTL1
Miscellaneous
canSAR (ICR)L3MBTL1 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineL3MBTL1
EVEXL3MBTL1
GoPubMedL3MBTL1
iHOPL3MBTL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:14:58 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.