LACTB2 (lactamase beta 2)

2014-08-01  

Identity

HGNC
LACTB2
LOCATION
8q13.3
LOCUSID
51110
ALIAS
CGI-83
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51110
MIM: 618921
HGNC: 18512
Ensembl: ENSG00000147592

Variants:

dbSNP: 51110
ClinVar: 51110
TCGA: ENSG00000147592
COSMIC: LACTB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147592ENST00000276590Q53H82
ENSG00000147592ENST00000276590A0A024R811
ENSG00000147592ENST00000522447Q53H82
ENSG00000147592ENST00000522447A0A024R811

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
258230272016Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer.9
268267082016Identification of LACTB2, a metallo-β-lactamase protein, as a human mitochondrial endoribonuclease.9
270054192016Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers.1

Citation

Dessen P

LACTB2 (lactamase beta 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54417/lactb2