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LAMB2 (laminin, beta 2 (laminin S))

Identity

Other namesLAMS
NPHS5
HGNC (Hugo) LAMB2
LocusID (NCBI) 3913
Location 3p21.31
Location_base_pair Starts at 49158547 and ends at 49170599 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LAMB2   6487
Cards
Entrez_Gene (NCBI)LAMB2  3913  laminin, beta 2 (laminin S)
GeneCards (Weizmann)LAMB2
Ensembl (Hinxton)ENSG00000172037 [Gene_View]  chr3:49158547-49170599 [Contig_View]  LAMB2 [Vega]
ICGC DataPortalENSG00000172037
cBioPortalLAMB2
AceView (NCBI)LAMB2
Genatlas (Paris)LAMB2
WikiGenes3913
SOURCE (Princeton)NM_002292
Genomic and cartography
GoldenPath (UCSC)LAMB2  -  3p21.31   chr3:49158547-49170599 -  3p21.31   [Description]    (hg19-Feb_2009)
EnsemblLAMB2 - 3p21.31 [CytoView]
Mapping of homologs : NCBILAMB2 [Mapview]
OMIM150325   609049   614199   
Gene and transcription
Genbank (Entrez)AK094050 BC172384 BP354643 CN265778 CN265784
RefSeq transcript (Entrez)NM_002292
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_008094 NT_022517 NW_001838877 NW_004929309
Consensus coding sequences : CCDS (NCBI)LAMB2
Cluster EST : UnigeneHs.439726 [ NCBI ]
CGAP (NCI)Hs.439726
Alternative Splicing : Fast-db (Paris)GSHG0021712
Alternative Splicing GalleryENSG00000172037
Gene ExpressionLAMB2 [ NCBI-GEO ]     LAMB2 [ SEEK ]   LAMB2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55268 (Uniprot)
NextProtP55268  [Medical]
With graphics : InterProP55268
Splice isoforms : SwissVarP55268 (Swissvar)
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_LAM_1 (PS01248)    EGF_LAM_2 (PS50027)    LAMININ_IVB (PS51116)    LAMININ_NTER (PS51117)   
Domains : Interpro (EBI)EGF-like_CS [organisation]   EGF_laminin [organisation]   Laminin_IV [organisation]   Laminin_N [organisation]  
Related proteins : CluSTrP55268
Domain families : Pfam (Sanger)Laminin_EGF (PF00053)    Laminin_N (PF00055)   
Domain families : Pfam (NCBI)pfam00053    pfam00055   
Domain families : Smart (EMBL)EGF_Lam (SM00180)  LamNT (SM00136)  
DMDM Disease mutations3913
Blocks (Seattle)P55268
Human Protein AtlasENSG00000172037 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP55268
HPRD01034
IPIIPI00296922   IPI00743203   
Protein Interaction databases
DIP (DOE-UCLA)P55268
IntAct (EBI)P55268
FunCoupENSG00000172037
BioGRIDLAMB2
InParanoidP55268
Interologous Interaction database P55268
IntegromeDBLAMB2
STRING (EMBL)LAMB2
Ontologies - Pathways
Ontology : AmiGOintegrin binding  structural molecule activity  extracellular region  basement membrane  basal lamina  laminin-3 complex  cell adhesion  axon guidance  neuromuscular junction development  visual perception  astrocyte development  Schwann cell development  extracellular matrix organization  extracellular matrix  extracellular matrix  laminin-11 complex  synapse  axon extension involved in regeneration  retina development in camera-type eye  extracellular vesicular exosome  metanephric glomerular visceral epithelial cell development  metanephric glomerular basement membrane development  
Ontology : EGO-EBIintegrin binding  structural molecule activity  extracellular region  basement membrane  basal lamina  laminin-3 complex  cell adhesion  axon guidance  neuromuscular junction development  visual perception  astrocyte development  Schwann cell development  extracellular matrix organization  extracellular matrix  extracellular matrix  laminin-11 complex  synapse  axon extension involved in regeneration  retina development in camera-type eye  extracellular vesicular exosome  metanephric glomerular visceral epithelial cell development  metanephric glomerular basement membrane development  
Pathways : KEGGPI3K-Akt signaling pathway    Focal adhesion    ECM-receptor interaction    Toxoplasmosis    Amoebiasis    Pathways in cancer    Small cell lung cancer   
Protein Interaction DatabaseLAMB2
Wikipedia pathwaysLAMB2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LAMB2
snp3D : Map Gene to Disease3913
SNP (GeneSNP Utah)LAMB2
SNP : HGBaseLAMB2
Genetic variants : HAPMAPLAMB2
Exome VariantLAMB2
1000_GenomesLAMB2 
ICGC programENSG00000172037 
Somatic Mutations in Cancer : COSMICLAMB2 
CONAN: Copy Number AnalysisLAMB2 
Mutations and Diseases : HGMDLAMB2
Mutations and Diseases : intOGenLAMB2
Genomic VariantsLAMB2  LAMB2 [DGVbeta]
dbVarLAMB2
ClinVarLAMB2
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM150325    609049    614199   
MedgenLAMB2
GENETestsLAMB2
Disease Genetic AssociationLAMB2
Huge Navigator LAMB2 [HugePedia]  LAMB2 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneLAMB2
Homology/Alignments : Family Browser (UCSC)LAMB2
Phylogenetic Trees/Animal Genes : TreeFamLAMB2
Chemical/Protein Interactions : CTD3913
Chemical/Pharm GKB GenePA164741827
Clinical trialLAMB2
Cancer Resource (Charite)ENSG00000172037
Other databases
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
CoreMineLAMB2
iHOPLAMB2
OncoSearchLAMB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:58:53 CEST 2014

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