Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LAMB2 (laminin, beta 2 (laminin S))

Identity

Other namesLAMS
NPHS5
HGNC (Hugo) LAMB2
LocusID (NCBI) 3913
Location 3p21.31
Location_base_pair Starts at 49158547 and ends at 49170599 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LAMB2   6487
Cards
Entrez_Gene (NCBI)LAMB2  3913  laminin, beta 2 (laminin S)
GeneCards (Weizmann)LAMB2
Ensembl hg19 (Hinxton)ENSG00000172037 [Gene_View]  chr3:49158547-49170599 [Contig_View]  LAMB2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000172037 [Gene_View]  chr3:49158547-49170599 [Contig_View]  LAMB2 [Vega]
ICGC DataPortalENSG00000172037
cBioPortalLAMB2
AceView (NCBI)LAMB2
Genatlas (Paris)LAMB2
WikiGenes3913
SOURCE (Princeton)LAMB2
Genomic and cartography
GoldenPath hg19 (UCSC)LAMB2  -     chr3:49158547-49170599 -  3p21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LAMB2  -     3p21.31   [Description]    (hg38-Dec_2013)
EnsemblLAMB2 - 3p21.31 [CytoView hg19]  LAMB2 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBILAMB2 [Mapview hg19]  LAMB2 [Mapview hg38]
OMIM150325   609049   614199   
Gene and transcription
Genbank (Entrez)AK094050 BC172384 BP354643 CN265778 CN265784
RefSeq transcript (Entrez)NM_002292
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_008094 NT_022517 NW_001838877 NW_004929309
Consensus coding sequences : CCDS (NCBI)LAMB2
Cluster EST : UnigeneHs.439726 [ NCBI ]
CGAP (NCI)Hs.439726
Alternative Splicing : Fast-db (Paris)GSHG0021712
Alternative Splicing GalleryENSG00000172037
Gene ExpressionLAMB2 [ NCBI-GEO ]     LAMB2 [ SEEK ]   LAMB2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55268 (Uniprot)
NextProtP55268  [Medical]
With graphics : InterProP55268
Splice isoforms : SwissVarP55268 (Swissvar)
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_LAM_1 (PS01248)    EGF_LAM_2 (PS50027)    LAMININ_IVB (PS51116)    LAMININ_NTER (PS51117)   
Domains : Interpro (EBI)EGF-like_CS    EGF_laminin    Laminin_IV    Laminin_N   
Related proteins : CluSTrP55268
Domain families : Pfam (Sanger)Laminin_EGF (PF00053)    Laminin_N (PF00055)   
Domain families : Pfam (NCBI)pfam00053    pfam00055   
Domain families : Smart (EMBL)EGF_Lam (SM00180)  LamNT (SM00136)  
DMDM Disease mutations3913
Blocks (Seattle)P55268
Human Protein AtlasENSG00000172037
Peptide AtlasP55268
HPRD01034
IPIIPI00296922   IPI00743203   
Protein Interaction databases
DIP (DOE-UCLA)P55268
IntAct (EBI)P55268
FunCoupENSG00000172037
BioGRIDLAMB2
IntegromeDBLAMB2
STRING (EMBL)LAMB2
Ontologies - Pathways
QuickGOP55268
Ontology : AmiGOintegrin binding  structural molecule activity  extracellular region  basement membrane  basal lamina  laminin-3 complex  cell adhesion  axon guidance  neuromuscular junction development  visual perception  astrocyte development  Schwann cell development  extracellular matrix organization  extracellular matrix  extracellular matrix  laminin-11 complex  synapse  axon extension involved in regeneration  retina development in camera-type eye  extracellular vesicular exosome  metanephric glomerular visceral epithelial cell development  metanephric glomerular basement membrane development  
Ontology : EGO-EBIintegrin binding  structural molecule activity  extracellular region  basement membrane  basal lamina  laminin-3 complex  cell adhesion  axon guidance  neuromuscular junction development  visual perception  astrocyte development  Schwann cell development  extracellular matrix organization  extracellular matrix  extracellular matrix  laminin-11 complex  synapse  axon extension involved in regeneration  retina development in camera-type eye  extracellular vesicular exosome  metanephric glomerular visceral epithelial cell development  metanephric glomerular basement membrane development  
Pathways : KEGGPI3K-Akt signaling pathway    Focal adhesion    ECM-receptor interaction    Toxoplasmosis    Amoebiasis    Pathways in cancer    Small cell lung cancer   
Protein Interaction DatabaseLAMB2
DoCM (Curated mutations)LAMB2
Wikipedia pathwaysLAMB2
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerLAMB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMB2
dbVarLAMB2
ClinVarLAMB2
1000_GenomesLAMB2 
Exome Variant ServerLAMB2
SNP (GeneSNP Utah)LAMB2
SNP : HGBaseLAMB2
Genetic variants : HAPMAPLAMB2
Genomic VariantsLAMB2  LAMB2 [DGVbeta]
Mutations
ICGC Data PortalENSG00000172037 
Somatic Mutations in Cancer : COSMICLAMB2 
CONAN: Copy Number AnalysisLAMB2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)Magdeburg Mutation Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:49158547-49170599
Mutations and Diseases : HGMDLAMB2
OMIM150325    609049    614199   
MedgenLAMB2
NextProtP55268 [Medical]
GENETestsLAMB2
Disease Genetic AssociationLAMB2
Huge Navigator LAMB2 [HugePedia]  LAMB2 [HugeCancerGEM]
snp3D : Map Gene to Disease3913
DGIdb (Drug Gene Interaction db)LAMB2
General knowledge
Homologs : HomoloGeneLAMB2
Homology/Alignments : Family Browser (UCSC)LAMB2
Phylogenetic Trees/Animal Genes : TreeFamLAMB2
Chemical/Protein Interactions : CTD3913
Chemical/Pharm GKB GenePA164741827
Clinical trialLAMB2
Cancer Resource (Charite)ENSG00000172037
Other databases
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
CoreMineLAMB2
GoPubMedLAMB2
iHOPLAMB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 22:24:51 CET 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.