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LAMB4 (laminin subunit beta 4)

Identity

Alias_nameslaminin
Other alias-
HGNC (Hugo) LAMB4
LocusID (NCBI) 22798
Atlas_Id 55196
Location 7q31.1  [Link to chromosome band 7q31]
Location_base_pair Starts at 108023551 and ends at 108130356 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LAMB1 (7q31.1) / LAMB4 (7q31.1)LAMB4 (7q31.1) / COBLL1 (2q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAMB4   6491
Cards
Entrez_Gene (NCBI)LAMB4  22798  laminin subunit beta 4
Aliases
GeneCards (Weizmann)LAMB4
Ensembl hg19 (Hinxton)ENSG00000091128 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000091128 [Gene_View]  chr7:108023551-108130356 [Contig_View]  LAMB4 [Vega]
ICGC DataPortalENSG00000091128
TCGA cBioPortalLAMB4
AceView (NCBI)LAMB4
Genatlas (Paris)LAMB4
WikiGenes22798
SOURCE (Princeton)LAMB4
Genetics Home Reference (NIH)LAMB4
Genomic and cartography
GoldenPath hg38 (UCSC)LAMB4  -     chr7:108023551-108130356 -  7q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LAMB4  -     7q31.1   [Description]    (hg19-Feb_2009)
EnsemblLAMB4 - 7q31.1 [CytoView hg19]  LAMB4 - 7q31.1 [CytoView hg38]
Mapping of homologs : NCBILAMB4 [Mapview hg19]  LAMB4 [Mapview hg38]
OMIM616380   
Gene and transcription
Genbank (Entrez)AF028816 AF029325 AK300385 AK301777 BC045172
RefSeq transcript (Entrez)NM_001318046 NM_001318047 NM_001318048 NM_007356
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LAMB4
Cluster EST : UnigeneHs.62022 [ NCBI ]
CGAP (NCI)Hs.62022
Alternative Splicing GalleryENSG00000091128
Gene ExpressionLAMB4 [ NCBI-GEO ]   LAMB4 [ EBI - ARRAY_EXPRESS ]   LAMB4 [ SEEK ]   LAMB4 [ MEM ]
Gene Expression Viewer (FireBrowse)LAMB4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22798
GTEX Portal (Tissue expression)LAMB4
Human Protein AtlasENSG00000091128-LAMB4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA4D0S4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA4D0S4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA4D0S4
Splice isoforms : SwissVarA4D0S4
PhosPhoSitePlusA4D0S4
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_LAM_1 (PS01248)    EGF_LAM_2 (PS50027)    LAMININ_IVB (PS51116)    LAMININ_NTER (PS51117)   
Domains : Interpro (EBI)Laminin_EGF    Laminin_IV_B    Laminin_N   
Domain families : Pfam (Sanger)Laminin_EGF (PF00053)    Laminin_N (PF00055)   
Domain families : Pfam (NCBI)pfam00053    pfam00055   
Domain families : Smart (EMBL)EGF_Lam (SM00180)  LamNT (SM00136)  
Conserved Domain (NCBI)LAMB4
DMDM Disease mutations22798
Blocks (Seattle)LAMB4
SuperfamilyA4D0S4
Human Protein Atlas [tissue]ENSG00000091128-LAMB4 [tissue]
Peptide AtlasA4D0S4
HPRD11224
IPIIPI00295437   IPI00852842   IPI00927194   IPI00939650   IPI00816232   
Protein Interaction databases
DIP (DOE-UCLA)A4D0S4
IntAct (EBI)A4D0S4
FunCoupENSG00000091128
BioGRIDLAMB4
STRING (EMBL)LAMB4
ZODIACLAMB4
Ontologies - Pathways
QuickGOA4D0S4
Ontology : AmiGObasement membrane  cell adhesion  
Ontology : EGO-EBIbasement membrane  cell adhesion  
Pathways : KEGGPI3K-Akt signaling pathway    Focal adhesion    ECM-receptor interaction    Toxoplasmosis    Amoebiasis    Pathways in cancer    Small cell lung cancer   
NDEx NetworkLAMB4
Atlas of Cancer Signalling NetworkLAMB4
Wikipedia pathwaysLAMB4
Orthology - Evolution
OrthoDB22798
GeneTree (enSembl)ENSG00000091128
Phylogenetic Trees/Animal Genes : TreeFamLAMB4
HOVERGENA4D0S4
HOGENOMA4D0S4
Homologs : HomoloGeneLAMB4
Homology/Alignments : Family Browser (UCSC)LAMB4
Gene fusions - Rearrangements
Fusion: Tumor Portal LAMB4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAMB4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMB4
dbVarLAMB4
ClinVarLAMB4
1000_GenomesLAMB4 
Exome Variant ServerLAMB4
ExAC (Exome Aggregation Consortium)ENSG00000091128
GNOMAD BrowserENSG00000091128
Genetic variants : HAPMAP22798
Genomic Variants (DGV)LAMB4 [DGVbeta]
DECIPHERLAMB4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLAMB4 
Mutations
ICGC Data PortalLAMB4 
TCGA Data PortalLAMB4 
Broad Tumor PortalLAMB4
OASIS PortalLAMB4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAMB4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLAMB4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LAMB4
DgiDB (Drug Gene Interaction Database)LAMB4
DoCM (Curated mutations)LAMB4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAMB4 (select a term)
intoGenLAMB4
Cancer3DLAMB4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616380   
Orphanet
MedgenLAMB4
Genetic Testing Registry LAMB4
NextProtA4D0S4 [Medical]
TSGene22798
GENETestsLAMB4
Target ValidationLAMB4
Huge Navigator LAMB4 [HugePedia]
snp3D : Map Gene to Disease22798
BioCentury BCIQLAMB4
ClinGenLAMB4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22798
Chemical/Pharm GKB GenePA30279
Clinical trialLAMB4
Miscellaneous
canSAR (ICR)LAMB4 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAMB4
EVEXLAMB4
GoPubMedLAMB4
iHOPLAMB4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:56:00 CET 2017

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