LAMB4 (laminin subunit beta 4)

2015-05-01  

Identity

HGNC
LOCATION
7q31.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 22798
MIM: 616380
HGNC: 6491
Ensembl: ENSG00000091128

Variants:

dbSNP: 22798
ClinVar: 22798
TCGA: ENSG00000091128
COSMIC: LAMB4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000091128ENST00000205386A4D0S4
ENSG00000091128ENST00000388781A4D0S4
ENSG00000091128ENST00000418464C9JMJ0
ENSG00000091128ENST00000422975A0A0C4DG90

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
ECM-receptor interactionKEGGko04512
Small cell lung cancerKEGGko05222
Focal adhesionKEGGhsa04510
ECM-receptor interactionKEGGhsa04512
Pathways in cancerKEGGhsa05200
Small cell lung cancerKEGGhsa05222
AmoebiasisKEGGko05146
AmoebiasisKEGGhsa05146
ToxoplasmosisKEGGko05145
ToxoplasmosisKEGGhsa05145
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
194016822010High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.52
285952692017Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing.7
252571912015Laminin gene LAMB4 is somatically mutated and expressionally altered in gastric and colorectal cancers.6

Citation

Dessen P

LAMB4 (laminin subunit beta 4)

Atlas Genet Cytogenet Oncol Haematol. 2015-05-01

Online version: http://atlasgeneticsoncology.org/gene/55196/lamb4