Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LAMC1 (laminin subunit gamma 1)

Identity

Alias_namesLAMB2
laminin
HGNC (Hugo) LAMC1
LocusID (NCBI) 3915
Atlas_Id 41118
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 182992595 and ends at 183114727 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
C1orf21 (1q25.3) / LAMC1 (1q25.3)LAMC1 (1q25.3) / GDPD5 (11q13.4)LAMC1 (1q25.3) / GNAI3 (1p13.3)
LAMC1 (1q25.3) / LAMC1 (1q25.3)LAMC1 (1q25.3) / TRIM5 (11p15.4)LAMC1 (1q25.3) / WNK1 (12p13.33)
LAMC2 (1q25.3) / LAMC1 (1q25.3)TLK2 (17q23.2) / LAMC1 (1q25.3)C1orf21 1q25.3 / LAMC1 1q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAMC1   6492
Cards
Entrez_Gene (NCBI)LAMC1  3915  laminin subunit gamma 1
AliasesLAMB2
GeneCards (Weizmann)LAMC1
Ensembl hg19 (Hinxton)ENSG00000135862 [Gene_View]  chr1:182992595-183114727 [Contig_View]  LAMC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000135862 [Gene_View]  chr1:182992595-183114727 [Contig_View]  LAMC1 [Vega]
ICGC DataPortalENSG00000135862
TCGA cBioPortalLAMC1
AceView (NCBI)LAMC1
Genatlas (Paris)LAMC1
WikiGenes3915
SOURCE (Princeton)LAMC1
Genetics Home Reference (NIH)LAMC1
Genomic and cartography
GoldenPath hg19 (UCSC)LAMC1  -     chr1:182992595-183114727 +  1q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LAMC1  -     1q25.3   [Description]    (hg38-Dec_2013)
EnsemblLAMC1 - 1q25.3 [CytoView hg19]  LAMC1 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBILAMC1 [Mapview hg19]  LAMC1 [Mapview hg38]
OMIM150290   
Gene and transcription
Genbank (Entrez)BC015586 BC035429 BC067813 BF507385 BI768612
RefSeq transcript (Entrez)NM_002293
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_011463 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)LAMC1
Cluster EST : UnigeneHs.609663 [ NCBI ]
CGAP (NCI)Hs.609663
Alternative Splicing GalleryENSG00000135862
Gene ExpressionLAMC1 [ NCBI-GEO ]   LAMC1 [ EBI - ARRAY_EXPRESS ]   LAMC1 [ SEEK ]   LAMC1 [ MEM ]
Gene Expression Viewer (FireBrowse)LAMC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3915
GTEX Portal (Tissue expression)LAMC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11047   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP11047  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11047
Splice isoforms : SwissVarP11047
PhosPhoSitePlusP11047
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_LAM_1 (PS01248)    EGF_LAM_2 (PS50027)    LAMININ_IVA (PS51115)    LAMININ_NTER (PS51117)   
Domains : Interpro (EBI)Galactose-bd-like    Laminin_EGF    Laminin_IV    Laminin_N   
Domain families : Pfam (Sanger)Laminin_B (PF00052)    Laminin_EGF (PF00053)    Laminin_N (PF00055)   
Domain families : Pfam (NCBI)pfam00052    pfam00053    pfam00055   
Domain families : Smart (EMBL)EGF_Lam (SM00180)  LamB (SM00281)  LamNT (SM00136)  
Conserved Domain (NCBI)LAMC1
DMDM Disease mutations3915
Blocks (Seattle)LAMC1
SuperfamilyP11047
Human Protein AtlasENSG00000135862
Peptide AtlasP11047
HPRD01030
IPIIPI00298281   IPI00409735   
Protein Interaction databases
DIP (DOE-UCLA)P11047
IntAct (EBI)P11047
FunCoupENSG00000135862
BioGRIDLAMC1
STRING (EMBL)LAMC1
ZODIACLAMC1
Ontologies - Pathways
QuickGOP11047
Ontology : AmiGOextracellular matrix structural constituent  extracellular region  basement membrane  laminin-1 complex  laminin-1 complex  extracellular space  protein complex assembly  cell adhesion  endoderm development  cell migration  extracellular matrix disassembly  extracellular matrix organization  extracellular matrix  extracellular matrix  extracellular matrix  hemidesmosome assembly  substrate adhesion-dependent cell spreading  laminin-10 complex  laminin-11 complex  positive regulation of epithelial cell proliferation  extracellular exosome  
Ontology : EGO-EBIextracellular matrix structural constituent  extracellular region  basement membrane  laminin-1 complex  laminin-1 complex  extracellular space  protein complex assembly  cell adhesion  endoderm development  cell migration  extracellular matrix disassembly  extracellular matrix organization  extracellular matrix  extracellular matrix  extracellular matrix  hemidesmosome assembly  substrate adhesion-dependent cell spreading  laminin-10 complex  laminin-11 complex  positive regulation of epithelial cell proliferation  extracellular exosome  
Pathways : BIOCARTAPrion Pathway [Genes]   
Pathways : KEGGPI3K-Akt signaling pathway    Focal adhesion    ECM-receptor interaction    Prion diseases    Toxoplasmosis    Amoebiasis    Pathways in cancer    Small cell lung cancer   
NDEx NetworkLAMC1
Atlas of Cancer Signalling NetworkLAMC1
Wikipedia pathwaysLAMC1
Orthology - Evolution
OrthoDB3915
GeneTree (enSembl)ENSG00000135862
Phylogenetic Trees/Animal Genes : TreeFamLAMC1
HOVERGENP11047
HOGENOMP11047
Homologs : HomoloGeneLAMC1
Homology/Alignments : Family Browser (UCSC)LAMC1
Gene fusions - Rearrangements
Fusion : MitelmanC1orf21/LAMC1 [1q25.3/1q25.3]  [t(1;1)(q25;q25)]  
Fusion: TCGAC1orf21 1q25.3 LAMC1 1q25.3 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAMC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMC1
dbVarLAMC1
ClinVarLAMC1
1000_GenomesLAMC1 
Exome Variant ServerLAMC1
ExAC (Exome Aggregation Consortium)LAMC1 (select the gene name)
Genetic variants : HAPMAP3915
Genomic Variants (DGV)LAMC1 [DGVbeta]
DECIPHER (Syndromes)1:182992595-183114727  ENSG00000135862
CONAN: Copy Number AnalysisLAMC1 
Mutations
ICGC Data PortalLAMC1 
TCGA Data PortalLAMC1 
Broad Tumor PortalLAMC1
OASIS PortalLAMC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAMC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLAMC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch LAMC1
DgiDB (Drug Gene Interaction Database)LAMC1
DoCM (Curated mutations)LAMC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAMC1 (select a term)
intoGenLAMC1
Cancer3DLAMC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM150290   
Orphanet
MedgenLAMC1
Genetic Testing Registry LAMC1
NextProtP11047 [Medical]
TSGene3915
GENETestsLAMC1
Huge Navigator LAMC1 [HugePedia]
snp3D : Map Gene to Disease3915
BioCentury BCIQLAMC1
ClinGenLAMC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3915
Chemical/Pharm GKB GenePA30280
Clinical trialLAMC1
Miscellaneous
canSAR (ICR)LAMC1 (select the gene name)
Probes
Litterature
PubMed101 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAMC1
EVEXLAMC1
GoPubMedLAMC1
iHOPLAMC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:41:34 CET 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.