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LAMC2 (laminin, gamma 2)

Identity

Other namesB2T
BM600
CSF
EBR2
EBR2A
LAMB2T
LAMNB2
HGNC (Hugo) LAMC2
LocusID (NCBI) 3918
Atlas_Id 41119
Location 1q25.3
Location_base_pair Starts at 183155174 and ends at 183214262 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LAMC2   6493
Cards
Entrez_Gene (NCBI)LAMC2  3918  laminin, gamma 2
GeneCards (Weizmann)LAMC2
Ensembl hg19 (Hinxton)ENSG00000058085 [Gene_View]  chr1:183155174-183214262 [Contig_View]  LAMC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000058085 [Gene_View]  chr1:183155174-183214262 [Contig_View]  LAMC2 [Vega]
ICGC DataPortalENSG00000058085
TCGA cBioPortalLAMC2
AceView (NCBI)LAMC2
Genatlas (Paris)LAMC2
WikiGenes3918
SOURCE (Princeton)LAMC2
Genomic and cartography
GoldenPath hg19 (UCSC)LAMC2  -     chr1:183155174-183214262 +  1q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LAMC2  -     1q25.3   [Description]    (hg38-Dec_2013)
EnsemblLAMC2 - 1q25.3 [CytoView hg19]  LAMC2 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBILAMC2 [Mapview hg19]  LAMC2 [Mapview hg38]
OMIM150292   226650   226700   
Gene and transcription
Genbank (Entrez)AK296944 AK307945 BC112286 BC113378 BC143653
RefSeq transcript (Entrez)NM_005562 NM_018891
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_007079 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)LAMC2
Cluster EST : UnigeneHs.591484 [ NCBI ]
CGAP (NCI)Hs.591484
Alternative Splicing : Fast-db (Paris)GSHG0001259
Alternative Splicing GalleryENSG00000058085
Gene ExpressionLAMC2 [ NCBI-GEO ]     LAMC2 [ SEEK ]   LAMC2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13753 (Uniprot)
NextProtQ13753  [Medical]
With graphics : InterProQ13753
Splice isoforms : SwissVarQ13753 (Swissvar)
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_LAM_1 (PS01248)    EGF_LAM_2 (PS50027)    LAMININ_IVA (PS51115)   
Domains : Interpro (EBI)EGF_laminin    Laminin_B_subgr    Laminin_B_type_IV   
Related proteins : CluSTrQ13753
Domain families : Pfam (Sanger)Laminin_B (PF00052)    Laminin_EGF (PF00053)   
Domain families : Pfam (NCBI)pfam00052    pfam00053   
Domain families : Smart (EMBL)EGF_Lam (SM00180)  LamB (SM00281)  
DMDM Disease mutations3918
Blocks (Seattle)Q13753
Human Protein AtlasENSG00000058085
Peptide AtlasQ13753
HPRD01031
IPIIPI00015117   IPI00220572   IPI01012321   
Protein Interaction databases
DIP (DOE-UCLA)Q13753
IntAct (EBI)Q13753
FunCoupENSG00000058085
BioGRIDLAMC2
IntegromeDBLAMC2
STRING (EMBL)LAMC2
Ontologies - Pathways
QuickGOQ13753
Ontology : AmiGOextracellular region  laminin-2 complex  laminin-5 complex  extracellular space  cell cortex  cell adhesion  heparin binding  epidermis development  membrane  extracellular matrix disassembly  extracellular matrix organization  hemidesmosome assembly  cell junction assembly  perinuclear region of cytoplasm  
Ontology : EGO-EBIextracellular region  laminin-2 complex  laminin-5 complex  extracellular space  cell cortex  cell adhesion  heparin binding  epidermis development  membrane  extracellular matrix disassembly  extracellular matrix organization  hemidesmosome assembly  cell junction assembly  perinuclear region of cytoplasm  
Pathways : KEGGPI3K-Akt signaling pathway    Focal adhesion    ECM-receptor interaction    Toxoplasmosis    Amoebiasis    Pathways in cancer    Small cell lung cancer   
Protein Interaction DatabaseLAMC2
DoCM (Curated mutations)LAMC2
Wikipedia pathwaysLAMC2
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerLAMC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMC2
dbVarLAMC2
ClinVarLAMC2
1000_GenomesLAMC2 
Exome Variant ServerLAMC2
SNP (GeneSNP Utah)LAMC2
SNP : HGBaseLAMC2
Genetic variants : HAPMAPLAMC2
Genomic Variants (DGV)LAMC2 [DGVbeta]
Mutations
ICGC Data PortalLAMC2 
TCGA Data PortalLAMC2 
Tumor PortalLAMC2
Somatic Mutations in Cancer : COSMICLAMC2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:183155174-183214262
CONAN: Copy Number AnalysisLAMC2 
Mutations and Diseases : HGMDLAMC2
OMIM150292    226650    226700   
MedgenLAMC2
NextProtQ13753 [Medical]
GENETestsLAMC2
Disease Genetic AssociationLAMC2
Huge Navigator LAMC2 [HugePedia]  LAMC2 [HugeCancerGEM]
snp3D : Map Gene to Disease3918
DGIdb (Drug Gene Interaction db)LAMC2
General knowledge
Homologs : HomoloGeneLAMC2
Homology/Alignments : Family Browser (UCSC)LAMC2
Phylogenetic Trees/Animal Genes : TreeFamLAMC2
Chemical/Protein Interactions : CTD3918
Chemical/Pharm GKB GenePA30281
Clinical trialLAMC2
Cancer Resource (Charite)ENSG00000058085
Other databases
Probes
Litterature
PubMed114 Pubmed reference(s) in Entrez
CoreMineLAMC2
GoPubMedLAMC2
iHOPLAMC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 19:32:13 CEST 2015

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