Atlas of Genetics and Cytogenetics in Oncology and Haematology

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LAMP1 (lysosomal associated membrane protein 1)

Identity

Alias (NCBI)CD107a
LAMPA
LGP120
HGNC (Hugo) LAMP1
HGNC Alias symbCD107a
HGNC Previous namelysosomal-associated membrane protein 1
LocusID (NCBI) 3916
Atlas_Id 41121
Location 13q34  [Link to chromosome band 13q34]
Location_base_pair Starts at 113297239 and ends at 113323672 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BTN2A1 (6p22.2) / LAMP1 (13q34)LAMP1 (13q34) / MCF2L (13q34)LAMP1 (13q34) / PSD (10q24.32)
LAMP1 (13q34) / ZER1 (9q34.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LAMP1   6499
Cards
Entrez_Gene (NCBI)LAMP1    lysosomal associated membrane protein 1
AliasesCD107a; LAMPA; LGP120
GeneCards (Weizmann)LAMP1
Ensembl hg19 (Hinxton)ENSG00000185896 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185896 [Gene_View]  ENSG00000185896 [Sequence]  chr13:113297239-113323672 [Contig_View]  LAMP1 [Vega]
ICGC DataPortalENSG00000185896
TCGA cBioPortalLAMP1
AceView (NCBI)LAMP1
Genatlas (Paris)LAMP1
SOURCE (Princeton)LAMP1
Genetics Home Reference (NIH)LAMP1
Genomic and cartography
GoldenPath hg38 (UCSC)LAMP1  -     chr13:113297239-113323672 +  13q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LAMP1  -     13q34   [Description]    (hg19-Feb_2009)
GoldenPathLAMP1 - 13q34 [CytoView hg19]  LAMP1 - 13q34 [CytoView hg38]
ImmunoBaseENSG00000185896
genome Data Viewer NCBILAMP1 [Mapview hg19]  
OMIM153330   
Gene and transcription
Genbank (Entrez)AB209319 AK092398 AK301584 BC006345 BC007845
RefSeq transcript (Entrez)NM_005561
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LAMP1
Alternative Splicing GalleryENSG00000185896
Gene ExpressionLAMP1 [ NCBI-GEO ]   LAMP1 [ EBI - ARRAY_EXPRESS ]   LAMP1 [ SEEK ]   LAMP1 [ MEM ]
Gene Expression Viewer (FireBrowse)LAMP1 [ Firebrowse - Broad ]
GenevisibleExpression of LAMP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3916
GTEX Portal (Tissue expression)LAMP1
Human Protein AtlasENSG00000185896-LAMP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11279   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP11279  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11279
Splice isoforms : SwissVarP11279
PhosPhoSitePlusP11279
Domaine pattern : Prosite (Expaxy)LAMP_1 (PS00310)    LAMP_2 (PS00311)    LAMP_3 (PS51407)   
Domains : Interpro (EBI)LAMP_CS    Lysosome-assoc_membr_glycop   
Domain families : Pfam (Sanger)Lamp (PF01299)   
Domain families : Pfam (NCBI)pfam01299   
Conserved Domain (NCBI)LAMP1
Blocks (Seattle)LAMP1
SuperfamilyP11279
Human Protein Atlas [tissue]ENSG00000185896-LAMP1 [tissue]
Peptide AtlasP11279
HPRD01076
IPIIPI00884105   IPI00908532   IPI00556655   
Protein Interaction databases
DIP (DOE-UCLA)P11279
IntAct (EBI)P11279
BioGRIDLAMP1
STRING (EMBL)LAMP1
ZODIACLAMP1
Ontologies - Pathways
QuickGOP11279
Ontology : AmiGOautophagosome membrane  virus receptor activity  protein binding  cytoplasm  lysosome  lysosome  lysosomal membrane  lysosomal membrane  late endosome  multivesicular body  cytosol  plasma membrane  plasma membrane  plasma membrane  integral component of plasma membrane  external side of plasma membrane  endosome membrane  membrane  enzyme binding  protein domain specific binding  integral component of synaptic vesicle membrane  dendrite  late endosome membrane  azurophil granule membrane  sarcolemma  melanosome  neuronal cell body  neutrophil degranulation  positive regulation of natural killer cell degranulation  cytolytic granule  autolysosome  positive regulation of natural killer cell mediated cytotoxicity  viral entry into host cell  autophagic cell death  perinuclear region of cytoplasm  protein stabilization  phagolysosome membrane  extracellular exosome  establishment of protein localization to organelle  establishment of protein localization to organelle  Golgi to lysosome transport  alveolar lamellar body  ficolin-1-rich granule membrane  granzyme-mediated programmed cell death signaling pathway  regulation of organelle transport along microtubule  
Ontology : EGO-EBIautophagosome membrane  virus receptor activity  protein binding  cytoplasm  lysosome  lysosome  lysosomal membrane  lysosomal membrane  late endosome  multivesicular body  cytosol  plasma membrane  plasma membrane  plasma membrane  integral component of plasma membrane  external side of plasma membrane  endosome membrane  membrane  enzyme binding  protein domain specific binding  integral component of synaptic vesicle membrane  dendrite  late endosome membrane  azurophil granule membrane  sarcolemma  melanosome  neuronal cell body  neutrophil degranulation  positive regulation of natural killer cell degranulation  cytolytic granule  autolysosome  positive regulation of natural killer cell mediated cytotoxicity  viral entry into host cell  autophagic cell death  perinuclear region of cytoplasm  protein stabilization  phagolysosome membrane  extracellular exosome  establishment of protein localization to organelle  establishment of protein localization to organelle  Golgi to lysosome transport  alveolar lamellar body  ficolin-1-rich granule membrane  granzyme-mediated programmed cell death signaling pathway  regulation of organelle transport along microtubule  
Pathways : KEGGLysosome    Phagosome    Tuberculosis   
NDEx NetworkLAMP1
Atlas of Cancer Signalling NetworkLAMP1
Wikipedia pathwaysLAMP1
Orthology - Evolution
OrthoDB3916
GeneTree (enSembl)ENSG00000185896
Phylogenetic Trees/Animal Genes : TreeFamLAMP1
HOGENOMP11279
Homologs : HomoloGeneLAMP1
Homology/Alignments : Family Browser (UCSC)LAMP1
Gene fusions - Rearrangements
Fusion : QuiverLAMP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAMP1 [hg38]
dbVarLAMP1
ClinVarLAMP1
MonarchLAMP1
1000_GenomesLAMP1 
Exome Variant ServerLAMP1
GNOMAD BrowserENSG00000185896
Varsome BrowserLAMP1
Genomic Variants (DGV)LAMP1 [DGVbeta]
DECIPHERLAMP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLAMP1 
Mutations
ICGC Data PortalLAMP1 
TCGA Data PortalLAMP1 
Broad Tumor PortalLAMP1
OASIS PortalLAMP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAMP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLAMP1
Mutations and Diseases : HGMDLAMP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LAMP1
DgiDB (Drug Gene Interaction Database)LAMP1
DoCM (Curated mutations)LAMP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAMP1 (select a term)
intoGenLAMP1
Cancer3DLAMP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM153330   
Orphanet
DisGeNETLAMP1
MedgenLAMP1
Genetic Testing Registry LAMP1
NextProtP11279 [Medical]
GENETestsLAMP1
Target ValidationLAMP1
Huge Navigator LAMP1 [HugePedia]
ClinGenLAMP1
Clinical trials, drugs, therapy
MyCancerGenomeLAMP1
Protein Interactions : CTD
Pharm GKB GenePA30283
PharosP11279
Clinical trialLAMP1
Miscellaneous
canSAR (ICR)LAMP1 (select the gene name)
HarmonizomeLAMP1
DataMed IndexLAMP1
Probes
Litterature
PubMed167 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLAMP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:28:33 CET 2021
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