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LAMP1 (lysosomal-associated membrane protein 1)

Identity

Other namesCD107a
LAMPA
LGP120
HGNC (Hugo) LAMP1
LocusID (NCBI) 3916
Location 13q34
Location_base_pair Starts at 113951469 and ends at 113977741 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LAMP1   6499
Cards
Entrez_Gene (NCBI)LAMP1  3916  lysosomal-associated membrane protein 1
GeneCards (Weizmann)LAMP1
Ensembl hg19 (Hinxton)ENSG00000185896 [Gene_View]  chr13:113951469-113977741 [Contig_View]  LAMP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000185896 [Gene_View]  chr13:113951469-113977741 [Contig_View]  LAMP1 [Vega]
ICGC DataPortalENSG00000185896
cBioPortalLAMP1
AceView (NCBI)LAMP1
Genatlas (Paris)LAMP1
WikiGenes3916
SOURCE (Princeton)LAMP1
Genomic and cartography
GoldenPath hg19 (UCSC)LAMP1  -     chr13:113951469-113977741 +  13q34   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LAMP1  -     13q34   [Description]    (hg38-Dec_2013)
EnsemblLAMP1 - 13q34 [CytoView hg19]  LAMP1 - 13q34 [CytoView hg38]
Mapping of homologs : NCBILAMP1 [Mapview hg19]  LAMP1 [Mapview hg38]
OMIM153330   
Gene and transcription
Genbank (Entrez)AB209319 AK092398 AK301584 BC006345 BC007845
RefSeq transcript (Entrez)NM_005561
RefSeq genomic (Entrez)AC_000145 NC_000013 NC_018924 NT_027140 NW_001838085 NW_004929390
Consensus coding sequences : CCDS (NCBI)LAMP1
Cluster EST : UnigeneHs.494419 [ NCBI ]
CGAP (NCI)Hs.494419
Alternative Splicing : Fast-db (Paris)GSHG0008314
Alternative Splicing GalleryENSG00000185896
Gene ExpressionLAMP1 [ NCBI-GEO ]     LAMP1 [ SEEK ]   LAMP1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11279 (Uniprot)
NextProtP11279  [Medical]
With graphics : InterProP11279
Splice isoforms : SwissVarP11279 (Swissvar)
Domaine pattern : Prosite (Expaxy)LAMP_1 (PS00310)    LAMP_2 (PS00311)    LAMP_3 (PS51407)   
Domains : Interpro (EBI)LAMP_CS    Lysosome-assoc_membr_glycop   
Related proteins : CluSTrP11279
Domain families : Pfam (Sanger)Lamp (PF01299)   
Domain families : Pfam (NCBI)pfam01299   
DMDM Disease mutations3916
Blocks (Seattle)P11279
Human Protein AtlasENSG00000185896
Peptide AtlasP11279
HPRD01076
IPIIPI00884105   IPI00908532   IPI00556655   
Protein Interaction databases
DIP (DOE-UCLA)P11279
IntAct (EBI)P11279
FunCoupENSG00000185896
BioGRIDLAMP1
IntegromeDBLAMP1
STRING (EMBL)LAMP1
Ontologies - Pathways
QuickGOP11279
Ontology : AmiGOprotein binding  cytoplasm  lysosome  lysosome  lysosomal membrane  late endosome  multivesicular body  integral component of plasma membrane  autophagy  granzyme-mediated apoptotic signaling pathway  external side of plasma membrane  endosome membrane  membrane  enzyme binding  dendrite  sarcolemma  melanosome  neuronal cell body  positive regulation of natural killer cell degranulation  cytolytic granule  positive regulation of natural killer cell mediated cytotoxicity  autophagic cell death  protein stabilization  extracellular vesicular exosome  establishment of protein localization to organelle  Golgi to lysosome transport  alveolar lamellar body  regulation of organelle transport along microtubule  
Ontology : EGO-EBIprotein binding  cytoplasm  lysosome  lysosome  lysosomal membrane  late endosome  multivesicular body  integral component of plasma membrane  autophagy  granzyme-mediated apoptotic signaling pathway  external side of plasma membrane  endosome membrane  membrane  enzyme binding  dendrite  sarcolemma  melanosome  neuronal cell body  positive regulation of natural killer cell degranulation  cytolytic granule  positive regulation of natural killer cell mediated cytotoxicity  autophagic cell death  protein stabilization  extracellular vesicular exosome  establishment of protein localization to organelle  Golgi to lysosome transport  alveolar lamellar body  regulation of organelle transport along microtubule  
Pathways : KEGGLysosome    Phagosome    Tuberculosis   
Protein Interaction DatabaseLAMP1
DoCM (Curated mutations)LAMP1
Wikipedia pathwaysLAMP1
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerLAMP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMP1
dbVarLAMP1
ClinVarLAMP1
1000_GenomesLAMP1 
Exome Variant ServerLAMP1
SNP (GeneSNP Utah)LAMP1
SNP : HGBaseLAMP1
Genetic variants : HAPMAPLAMP1
Genomic VariantsLAMP1  LAMP1 [DGVbeta]
Mutations
ICGC Data PortalENSG00000185896 
Somatic Mutations in Cancer : COSMICLAMP1 
CONAN: Copy Number AnalysisLAMP1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)13:113951469-113977741
Mutations and Diseases : HGMDLAMP1
OMIM153330   
MedgenLAMP1
NextProtP11279 [Medical]
GENETestsLAMP1
Disease Genetic AssociationLAMP1
Huge Navigator LAMP1 [HugePedia]  LAMP1 [HugeCancerGEM]
snp3D : Map Gene to Disease3916
DGIdb (Drug Gene Interaction db)LAMP1
General knowledge
Homologs : HomoloGeneLAMP1
Homology/Alignments : Family Browser (UCSC)LAMP1
Phylogenetic Trees/Animal Genes : TreeFamLAMP1
Chemical/Protein Interactions : CTD3916
Chemical/Pharm GKB GenePA30283
Clinical trialLAMP1
Cancer Resource (Charite)ENSG00000185896
Other databases
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
CoreMineLAMP1
GoPubMedLAMP1
iHOPLAMP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 22:24:56 CET 2014

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