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LAMP1 (lysosomal associated membrane protein 1)

Identity

Other namesCD107a
LAMPA
LGP120
HGNC (Hugo) LAMP1
LocusID (NCBI) 3916
Atlas_Id 41121
Location 13q34  [Link to chromosome band 13q34]
Location_base_pair Starts at 113951469 and ends at 113977741 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)		BTN2A1 (6p22.2) / LAMP1 (13q34)LAMP1 (13q34) / MCF2L (13q34)LAMP1 (13q34) / PSD (10q24.32)
LAMP1 (13q34) / ZER1 (9q34.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LAMP1   6499
Cards
Entrez_Gene (NCBI)LAMP1  3916  lysosomal associated membrane protein 1
AliasesCD107a; LAMPA; LGP120
GeneCards (Weizmann)LAMP1
Ensembl hg19 (Hinxton)ENSG00000185896 [Gene_View]  chr13:113951469-113977741 [Contig_View]  LAMP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000185896 [Gene_View]  chr13:113951469-113977741 [Contig_View]  LAMP1 [Vega]
ICGC DataPortalENSG00000185896
TCGA cBioPortalLAMP1
AceView (NCBI)LAMP1
Genatlas (Paris)LAMP1
WikiGenes3916
SOURCE (Princeton)LAMP1
Genomic and cartography
GoldenPath hg19 (UCSC)LAMP1  -     chr13:113951469-113977741 +  13q34   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LAMP1  -     13q34   [Description]    (hg38-Dec_2013)
EnsemblLAMP1 - 13q34 [CytoView hg19]  LAMP1 - 13q34 [CytoView hg38]
Mapping of homologs : NCBILAMP1 [Mapview hg19]  LAMP1 [Mapview hg38]
OMIM153330   
Gene and transcription
Genbank (Entrez)AB209319 AK092398 AK301584 BC006345 BC007845
RefSeq transcript (Entrez)NM_005561
RefSeq genomic (Entrez)NC_000013 NC_018924 NT_027140 NW_004929390
Consensus coding sequences : CCDS (NCBI)LAMP1
Cluster EST : UnigeneHs.494419 [ NCBI ]
CGAP (NCI)Hs.494419
Alternative Splicing GalleryENSG00000185896
Gene ExpressionLAMP1 [ NCBI-GEO ]   LAMP1 [ EBI - ARRAY_EXPRESS ]   LAMP1 [ SEEK ]   LAMP1 [ MEM ]
Gene Expression Viewer (FireBrowse)LAMP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3916
GTEX Portal (Tissue expression)LAMP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11279 (Uniprot)
NextProtP11279  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11279
Splice isoforms : SwissVarP11279 (Swissvar)
PhosPhoSitePlusP11279
Domaine pattern : Prosite (Expaxy)LAMP_1 (PS00310)    LAMP_2 (PS00311)    LAMP_3 (PS51407)   
Domains : Interpro (EBI)LAMP_CS    Lysosome-assoc_membr_glycop   
Domain families : Pfam (Sanger)Lamp (PF01299)   
Domain families : Pfam (NCBI)pfam01299   
DMDM Disease mutations3916
Blocks (Seattle)LAMP1
SuperfamilyP11279
Human Protein AtlasENSG00000185896
Peptide AtlasP11279
HPRD01076
IPIIPI00884105   IPI00908532   IPI00556655   
Protein Interaction databases
DIP (DOE-UCLA)P11279
IntAct (EBI)P11279
FunCoupENSG00000185896
BioGRIDLAMP1
STRING (EMBL)LAMP1
ZODIACLAMP1
Ontologies - Pathways
QuickGOP11279
Ontology : AmiGOvirus receptor activity  protein binding  cytoplasm  lysosome  lysosome  lysosomal membrane  late endosome  multivesicular body  cytosol  plasma membrane  integral component of plasma membrane  autophagy  synaptic vesicle  granzyme-mediated apoptotic signaling pathway  external side of plasma membrane  endosome membrane  membrane  enzyme binding  protein domain specific binding  dendrite  sarcolemma  melanosome  neuronal cell body  positive regulation of natural killer cell degranulation  cytolytic granule  positive regulation of natural killer cell mediated cytotoxicity  viral entry into host cell  autophagic cell death  perinuclear region of cytoplasm  protein stabilization  phagolysosome membrane  extracellular exosome  establishment of protein localization to organelle  Golgi to lysosome transport  alveolar lamellar body  regulation of organelle transport along microtubule  
Ontology : EGO-EBIvirus receptor activity  protein binding  cytoplasm  lysosome  lysosome  lysosomal membrane  late endosome  multivesicular body  cytosol  plasma membrane  integral component of plasma membrane  autophagy  synaptic vesicle  granzyme-mediated apoptotic signaling pathway  external side of plasma membrane  endosome membrane  membrane  enzyme binding  protein domain specific binding  dendrite  sarcolemma  melanosome  neuronal cell body  positive regulation of natural killer cell degranulation  cytolytic granule  positive regulation of natural killer cell mediated cytotoxicity  viral entry into host cell  autophagic cell death  perinuclear region of cytoplasm  protein stabilization  phagolysosome membrane  extracellular exosome  establishment of protein localization to organelle  Golgi to lysosome transport  alveolar lamellar body  regulation of organelle transport along microtubule  
Pathways : KEGGLysosome    Phagosome    Tuberculosis   
NDEx NetworkLAMP1
Atlas of Cancer Signalling NetworkLAMP1
Wikipedia pathwaysLAMP1
Orthology - Evolution
OrthoDB3916
GeneTree (enSembl)ENSG00000185896
Phylogenetic Trees/Animal Genes : TreeFamLAMP1
Homologs : HomoloGeneLAMP1
Homology/Alignments : Family Browser (UCSC)LAMP1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerLAMP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMP1
dbVarLAMP1
ClinVarLAMP1
1000_GenomesLAMP1 
Exome Variant ServerLAMP1
ExAC (Exome Aggregation Consortium)LAMP1 (select the gene name)
Genetic variants : HAPMAP3916
Genomic Variants (DGV)LAMP1 [DGVbeta]
Mutations
ICGC Data PortalLAMP1 
TCGA Data PortalLAMP1 
Broad Tumor PortalLAMP1
OASIS PortalLAMP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAMP1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LAMP1
DgiDB (Drug Gene Interaction Database)LAMP1
DoCM (Curated mutations)LAMP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAMP1 (select a term)
intoGenLAMP1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)13:113951469-113977741  ENSG00000185896
CONAN: Copy Number AnalysisLAMP1 
Mutations and Diseases : HGMDLAMP1
OMIM153330   
MedgenLAMP1
Genetic Testing Registry LAMP1
NextProtP11279 [Medical]
TSGene3916
GENETestsLAMP1
Huge Navigator LAMP1 [HugePedia]
snp3D : Map Gene to Disease3916
BioCentury BCIQLAMP1
ClinGenLAMP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3916
Chemical/Pharm GKB GenePA30283
Clinical trialLAMP1
Miscellaneous
canSAR (ICR)LAMP1 (select the gene name)
Probes
Litterature
PubMed116 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAMP1
EVEXLAMP1
GoPubMedLAMP1
iHOPLAMP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 18:57:13 CEST 2016
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