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LAMP2 (lysosomal associated membrane protein 2)

Identity

Other namesCD107b
LAMP-2
LAMPB
LGP110
HGNC (Hugo) LAMP2
LocusID (NCBI) 3920
Atlas_Id 41122
Location Xq24  [Link to chromosome band Xq24]
Location_base_pair Starts at 119560003 and ends at 119603204 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
COL1A2 (7q21.3) / LAMP2 (Xq24)GATA2 (3q21.3) / LAMP2 (Xq24)LAMP2 (Xq24) / FNIP2 (4q32.1)
LAMP2 (Xq24) / LAMP2 (Xq24)MALAT1 (11q13.1) / LAMP2 (Xq24)POLR2I (19q13.12) / LAMP2 (Xq24)
SCARB2 (4q21.1) / LAMP2 (Xq24)WDR74 (11q12.3) / LAMP2 (Xq24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAMP2   6501
Cards
Entrez_Gene (NCBI)LAMP2  3920  lysosomal associated membrane protein 2
AliasesCD107b; LAMP-2; LAMPB; LGP110
GeneCards (Weizmann)LAMP2
Ensembl hg19 (Hinxton)ENSG00000005893 [Gene_View]  chrX:119560003-119603204 [Contig_View]  LAMP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000005893 [Gene_View]  chrX:119560003-119603204 [Contig_View]  LAMP2 [Vega]
ICGC DataPortalENSG00000005893
TCGA cBioPortalLAMP2
AceView (NCBI)LAMP2
Genatlas (Paris)LAMP2
WikiGenes3920
SOURCE (Princeton)LAMP2
Genomic and cartography
GoldenPath hg19 (UCSC)LAMP2  -     chrX:119560003-119603204 -  Xq24   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LAMP2  -     Xq24   [Description]    (hg38-Dec_2013)
EnsemblLAMP2 - Xq24 [CytoView hg19]  LAMP2 - Xq24 [CytoView hg38]
Mapping of homologs : NCBILAMP2 [Mapview hg19]  LAMP2 [Mapview hg38]
OMIM300257   309060   
Gene and transcription
Genbank (Entrez)AK291090 AK293931 AK295038 AK304405 AY561849
RefSeq transcript (Entrez)NM_001122606 NM_002294 NM_013995
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_007995 NT_011786 NW_004929446
Consensus coding sequences : CCDS (NCBI)LAMP2
Cluster EST : UnigeneHs.496684 [ NCBI ]
CGAP (NCI)Hs.496684
Alternative Splicing GalleryENSG00000005893
Gene ExpressionLAMP2 [ NCBI-GEO ]   LAMP2 [ EBI - ARRAY_EXPRESS ]   LAMP2 [ SEEK ]   LAMP2 [ MEM ]
Gene Expression Viewer (FireBrowse)LAMP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3920
GTEX Portal (Tissue expression)LAMP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13473 (Uniprot)
NextProtP13473  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP13473
Splice isoforms : SwissVarP13473 (Swissvar)
PhosPhoSitePlusP13473
Domaine pattern : Prosite (Expaxy)LAMP_1 (PS00310)    LAMP_2 (PS00311)    LAMP_3 (PS51407)   
Domains : Interpro (EBI)LAMP_CS    Lysosome-assoc_membr_glycop   
Domain families : Pfam (Sanger)Lamp (PF01299)   
Domain families : Pfam (NCBI)pfam01299   
DMDM Disease mutations3920
Blocks (Seattle)LAMP2
PDB (SRS)2MOF    2MOM   
PDB (PDBSum)2MOF    2MOM   
PDB (IMB)2MOF    2MOM   
PDB (RSDB)2MOF    2MOM   
Structural Biology KnowledgeBase2MOF    2MOM   
SCOP (Structural Classification of Proteins)2MOF    2MOM   
CATH (Classification of proteins structures)2MOF    2MOM   
SuperfamilyP13473
Human Protein AtlasENSG00000005893
Peptide AtlasP13473
HPRD02396
IPIIPI00009030   IPI00739827   IPI00910397   IPI00980890   IPI00922445   IPI00216172   
Protein Interaction databases
DIP (DOE-UCLA)P13473
IntAct (EBI)P13473
FunCoupENSG00000005893
BioGRIDLAMP2
STRING (EMBL)LAMP2
ZODIACLAMP2
Ontologies - Pathways
QuickGOP13473
Ontology : AmiGOplatelet degranulation  protein binding  extracellular space  lysosome  lysosomal membrane  late endosome  plasma membrane  membrane  integral component of membrane  protein import  enzyme binding  protein domain specific binding  phagocytic vesicle membrane  platelet dense granule membrane  platelet dense granule membrane  regulation of protein stability  late endosome membrane  lysosomal lumen  muscle cell cellular homeostasis  protein stabilization  chaperone-mediated autophagy  chaperone-mediated autophagy  chaperone-mediated autophagy translocation complex  extracellular exosome  membrane microdomain  
Ontology : EGO-EBIplatelet degranulation  protein binding  extracellular space  lysosome  lysosomal membrane  late endosome  plasma membrane  membrane  integral component of membrane  protein import  enzyme binding  protein domain specific binding  phagocytic vesicle membrane  platelet dense granule membrane  platelet dense granule membrane  regulation of protein stability  late endosome membrane  lysosomal lumen  muscle cell cellular homeostasis  protein stabilization  chaperone-mediated autophagy  chaperone-mediated autophagy  chaperone-mediated autophagy translocation complex  extracellular exosome  membrane microdomain  
Pathways : KEGGLysosome    Phagosome    Tuberculosis   
NDEx Network
Atlas of Cancer Signalling NetworkLAMP2
Wikipedia pathwaysLAMP2
Orthology - Evolution
OrthoDB3920
GeneTree (enSembl)ENSG00000005893
Phylogenetic Trees/Animal Genes : TreeFamLAMP2
Homologs : HomoloGeneLAMP2
Homology/Alignments : Family Browser (UCSC)LAMP2
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerLAMP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMP2
dbVarLAMP2
ClinVarLAMP2
1000_GenomesLAMP2 
Exome Variant ServerLAMP2
ExAC (Exome Aggregation Consortium)LAMP2 (select the gene name)
Genetic variants : HAPMAP3920
Genomic Variants (DGV)LAMP2 [DGVbeta]
Mutations
ICGC Data PortalLAMP2 
TCGA Data PortalLAMP2 
Broad Tumor PortalLAMP2
OASIS PortalLAMP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAMP2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)Leiden Muscular Dystrophy pages
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM)
BioMutasearch LAMP2
DgiDB (Drug Gene Interaction Database)LAMP2
DoCM (Curated mutations)LAMP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAMP2 (select a term)
intoGenLAMP2
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)X:119560003-119603204  ENSG00000005893
CONAN: Copy Number AnalysisLAMP2 
Mutations and Diseases : HGMDLAMP2
OMIM300257    309060   
MedgenLAMP2
Genetic Testing Registry LAMP2
NextProtP13473 [Medical]
TSGene3920
GENETestsLAMP2
Huge Navigator LAMP2 [HugePedia]
snp3D : Map Gene to Disease3920
BioCentury BCIQLAMP2
ClinGenLAMP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3920
Chemical/Pharm GKB GenePA30285
Clinical trialLAMP2
Miscellaneous
canSAR (ICR)LAMP2 (select the gene name)
Probes
Litterature
PubMed122 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAMP2
EVEXLAMP2
GoPubMedLAMP2
iHOPLAMP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 9 19:05:04 CEST 2016

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