LAMP3 (lysosomal associated membrane protein 3)

2003-02-01  

Identity

HGNC
LOCATION
3q27.1
LOCUSID
ALIAS
CD208,DC
FUSION GENES

Other Information

Locus ID:

NCBI: 27074
MIM: 605883
HGNC: 14582
Ensembl: ENSG00000078081

Variants:

dbSNP: 27074
ClinVar: 27074
TCGA: ENSG00000078081
COSMIC: LAMP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000078081ENST00000265598Q9UQV4
ENSG00000078081ENST00000466939E7ETP9
ENSG00000078081ENST00000470251C9JDI8
ENSG00000078081ENST00000476015C9JYP5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
232945422013Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response.82
240451832013Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3.41
236519942013Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer.35
182922342008Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles.33
162040312005Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer.32
253623572014Prognostic value of LAMP3 and TP53 overexpression in benign and malignant gastrointestinal tissues.31
193080212009Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.29
228093262012Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx.28
244347182014LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy.22

Citation

Dessen P

LAMP3 (lysosomal associated membrane protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41123/lamp3