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LAMP3 (lysosomal associated membrane protein 3)

Identity

Alias_nameslysosomal-associated membrane protein 3
Alias_symbol (synonym)LAMP
TSC403
DC-LAMP
DCLAMP
CD208
Other aliasDC LAMP
LAMP-3
HGNC (Hugo) LAMP3
LocusID (NCBI) 27074
Atlas_Id 41123
Location 3q27.1  [Link to chromosome band 3q27]
Location_base_pair Starts at 183122215 and ends at 183162879 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FGF12 (3q28) / LAMP3 (3q27.1)FGF12 3q28 / LAMP3 3q27.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAMP3   14582
Cards
Entrez_Gene (NCBI)LAMP3  27074  lysosomal associated membrane protein 3
AliasesCD208; DC; DC-LAMP; DCLAMP; 
LAMP; LAMP-3; TSC403
GeneCards (Weizmann)LAMP3
Ensembl hg19 (Hinxton)ENSG00000078081 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000078081 [Gene_View]  chr3:183122215-183162879 [Contig_View]  LAMP3 [Vega]
ICGC DataPortalENSG00000078081
TCGA cBioPortalLAMP3
AceView (NCBI)LAMP3
Genatlas (Paris)LAMP3
WikiGenes27074
SOURCE (Princeton)LAMP3
Genetics Home Reference (NIH)LAMP3
Genomic and cartography
GoldenPath hg38 (UCSC)LAMP3  -     chr3:183122215-183162879 -  3q27.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LAMP3  -     3q27.1   [Description]    (hg19-Feb_2009)
EnsemblLAMP3 - 3q27.1 [CytoView hg19]  LAMP3 - 3q27.1 [CytoView hg38]
Mapping of homologs : NCBILAMP3 [Mapview hg19]  LAMP3 [Mapview hg38]
OMIM605883   
Gene and transcription
Genbank (Entrez)AB013924 AJ005766 AK302894 AK313172 BC032940
RefSeq transcript (Entrez)NM_014398
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LAMP3
Cluster EST : UnigeneHs.518448 [ NCBI ]
CGAP (NCI)Hs.518448
Alternative Splicing GalleryENSG00000078081
Gene ExpressionLAMP3 [ NCBI-GEO ]   LAMP3 [ EBI - ARRAY_EXPRESS ]   LAMP3 [ SEEK ]   LAMP3 [ MEM ]
Gene Expression Viewer (FireBrowse)LAMP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27074
GTEX Portal (Tissue expression)LAMP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UQV4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UQV4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UQV4
Splice isoforms : SwissVarQ9UQV4
PhosPhoSitePlusQ9UQV4
Domaine pattern : Prosite (Expaxy)LAMP_3 (PS51407)   
Domains : Interpro (EBI)Lysosome-assoc_membr_glycop   
Domain families : Pfam (Sanger)Lamp (PF01299)   
Domain families : Pfam (NCBI)pfam01299   
Conserved Domain (NCBI)LAMP3
DMDM Disease mutations27074
Blocks (Seattle)LAMP3
PDB (SRS)4AKM   
PDB (PDBSum)4AKM   
PDB (IMB)4AKM   
PDB (RSDB)4AKM   
Structural Biology KnowledgeBase4AKM   
SCOP (Structural Classification of Proteins)4AKM   
CATH (Classification of proteins structures)4AKM   
SuperfamilyQ9UQV4
Human Protein AtlasENSG00000078081
Peptide AtlasQ9UQV4
HPRD12062
IPIIPI00004307   IPI00946356   IPI00947513   IPI00947332   
Protein Interaction databases
DIP (DOE-UCLA)Q9UQV4
IntAct (EBI)Q9UQV4
FunCoupENSG00000078081
BioGRIDLAMP3
STRING (EMBL)LAMP3
ZODIACLAMP3
Ontologies - Pathways
QuickGOQ9UQV4
Ontology : AmiGOadaptive immune response  nucleus  lysosome  lysosomal membrane  early endosome  plasma membrane  regulation of autophagy  positive regulation of gene expression  integral component of membrane  vesicle  response to interferon-alpha  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  intracellular membrane-bounded organelle  viral entry into host cell  perinuclear region of cytoplasm  alveolar lamellar body membrane  negative regulation of proteasomal protein catabolic process  regulation of viral life cycle  
Ontology : EGO-EBIadaptive immune response  nucleus  lysosome  lysosomal membrane  early endosome  plasma membrane  regulation of autophagy  positive regulation of gene expression  integral component of membrane  vesicle  response to interferon-alpha  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  intracellular membrane-bounded organelle  viral entry into host cell  perinuclear region of cytoplasm  alveolar lamellar body membrane  negative regulation of proteasomal protein catabolic process  regulation of viral life cycle  
Pathways : KEGGLysosome   
NDEx NetworkLAMP3
Atlas of Cancer Signalling NetworkLAMP3
Wikipedia pathwaysLAMP3
Orthology - Evolution
OrthoDB27074
GeneTree (enSembl)ENSG00000078081
Phylogenetic Trees/Animal Genes : TreeFamLAMP3
HOVERGENQ9UQV4
HOGENOMQ9UQV4
Homologs : HomoloGeneLAMP3
Homology/Alignments : Family Browser (UCSC)LAMP3
Gene fusions - Rearrangements
Fusion : MitelmanFGF12/LAMP3 [3q28/3q27.1]  [t(3;3)(q27;q29)]  
Fusion: TCGAFGF12 3q28 LAMP3 3q27.1 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAMP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMP3
dbVarLAMP3
ClinVarLAMP3
1000_GenomesLAMP3 
Exome Variant ServerLAMP3
ExAC (Exome Aggregation Consortium)LAMP3 (select the gene name)
Genetic variants : HAPMAP27074
Genomic Variants (DGV)LAMP3 [DGVbeta]
DECIPHERLAMP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLAMP3 
Mutations
ICGC Data PortalLAMP3 
TCGA Data PortalLAMP3 
Broad Tumor PortalLAMP3
OASIS PortalLAMP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAMP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLAMP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LAMP3
DgiDB (Drug Gene Interaction Database)LAMP3
DoCM (Curated mutations)LAMP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAMP3 (select a term)
intoGenLAMP3
Cancer3DLAMP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605883   
Orphanet
MedgenLAMP3
Genetic Testing Registry LAMP3
NextProtQ9UQV4 [Medical]
TSGene27074
GENETestsLAMP3
Target ValidationLAMP3
Huge Navigator LAMP3 [HugePedia]
snp3D : Map Gene to Disease27074
BioCentury BCIQLAMP3
ClinGenLAMP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27074
Chemical/Pharm GKB GenePA30286
Clinical trialLAMP3
Miscellaneous
canSAR (ICR)LAMP3 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAMP3
EVEXLAMP3
GoPubMedLAMP3
iHOPLAMP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Jun 7 12:40:11 CEST 2017

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