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LAMTOR4 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 4)

Identity

Alias_namesC7orf59
chromosome 7 open reading frame 59
Other alias
HGNC (Hugo) LAMTOR4
LocusID (NCBI) 389541
Atlas_Id 65167
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 100148899 and ends at 100154212 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAMTOR4   33772
Cards
Entrez_Gene (NCBI)LAMTOR4  389541  late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
AliasesC7orf59
GeneCards (Weizmann)LAMTOR4
Ensembl hg19 (Hinxton)ENSG00000188186 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188186 [Gene_View]  chr7:100148899-100154212 [Contig_View]  LAMTOR4 [Vega]
ICGC DataPortalENSG00000188186
TCGA cBioPortalLAMTOR4
AceView (NCBI)LAMTOR4
Genatlas (Paris)LAMTOR4
WikiGenes389541
SOURCE (Princeton)LAMTOR4
Genetics Home Reference (NIH)LAMTOR4
Genomic and cartography
GoldenPath hg38 (UCSC)LAMTOR4  -     chr7:100148899-100154212 +  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LAMTOR4  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblLAMTOR4 - 7q22.1 [CytoView hg19]  LAMTOR4 - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBILAMTOR4 [Mapview hg19]  LAMTOR4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA419348 AA772120 AJ714519 BC063401 BC105609
RefSeq transcript (Entrez)NM_001008395 NM_001318236 NM_001318237
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LAMTOR4
Cluster EST : UnigeneHs.406520 [ NCBI ]
CGAP (NCI)Hs.406520
Alternative Splicing GalleryENSG00000188186
Gene ExpressionLAMTOR4 [ NCBI-GEO ]   LAMTOR4 [ EBI - ARRAY_EXPRESS ]   LAMTOR4 [ SEEK ]   LAMTOR4 [ MEM ]
Gene Expression Viewer (FireBrowse)LAMTOR4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)389541
GTEX Portal (Tissue expression)LAMTOR4
Human Protein AtlasENSG00000188186-LAMTOR4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ0VGL1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ0VGL1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ0VGL1
Splice isoforms : SwissVarQ0VGL1
PhosPhoSitePlusQ0VGL1
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)LAMTOR4
DMDM Disease mutations389541
Blocks (Seattle)LAMTOR4
SuperfamilyQ0VGL1
Human Protein Atlas [tissue]ENSG00000188186-LAMTOR4 [tissue]
Peptide AtlasQ0VGL1
HPRD17380
IPIIPI00924667   IPI00925110   
Protein Interaction databases
DIP (DOE-UCLA)Q0VGL1
IntAct (EBI)Q0VGL1
FunCoupENSG00000188186
BioGRIDLAMTOR4
STRING (EMBL)LAMTOR4
ZODIACLAMTOR4
Ontologies - Pathways
QuickGOQ0VGL1
Ontology : AmiGOguanyl-nucleotide exchange factor activity  protein binding  lysosome  lysosomal membrane  cell cycle arrest  regulation of cell size  macroautophagy  positive regulation of TOR signaling  protein complex scaffold  intracellular membrane-bounded organelle  positive regulation of GTPase activity  protein localization to lysosome  cellular response to amino acid stimulus  Ragulator complex  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  protein binding  lysosome  lysosomal membrane  cell cycle arrest  regulation of cell size  macroautophagy  positive regulation of TOR signaling  protein complex scaffold  intracellular membrane-bounded organelle  positive regulation of GTPase activity  protein localization to lysosome  cellular response to amino acid stimulus  Ragulator complex  
NDEx NetworkLAMTOR4
Atlas of Cancer Signalling NetworkLAMTOR4
Wikipedia pathwaysLAMTOR4
Orthology - Evolution
OrthoDB389541
GeneTree (enSembl)ENSG00000188186
Phylogenetic Trees/Animal Genes : TreeFamLAMTOR4
HOVERGENQ0VGL1
HOGENOMQ0VGL1
Homologs : HomoloGeneLAMTOR4
Homology/Alignments : Family Browser (UCSC)LAMTOR4
Gene fusions - Rearrangements
Fusion: Tumor Portal LAMTOR4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAMTOR4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMTOR4
dbVarLAMTOR4
ClinVarLAMTOR4
1000_GenomesLAMTOR4 
Exome Variant ServerLAMTOR4
ExAC (Exome Aggregation Consortium)ENSG00000188186
GNOMAD BrowserENSG00000188186
Genetic variants : HAPMAP389541
Genomic Variants (DGV)LAMTOR4 [DGVbeta]
DECIPHERLAMTOR4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLAMTOR4 
Mutations
ICGC Data PortalLAMTOR4 
TCGA Data PortalLAMTOR4 
Broad Tumor PortalLAMTOR4
OASIS PortalLAMTOR4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDLAMTOR4
BioMutasearch LAMTOR4
DgiDB (Drug Gene Interaction Database)LAMTOR4
DoCM (Curated mutations)LAMTOR4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAMTOR4 (select a term)
intoGenLAMTOR4
Cancer3DLAMTOR4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenLAMTOR4
Genetic Testing Registry LAMTOR4
NextProtQ0VGL1 [Medical]
TSGene389541
GENETestsLAMTOR4
Target ValidationLAMTOR4
Huge Navigator LAMTOR4 [HugePedia]
snp3D : Map Gene to Disease389541
BioCentury BCIQLAMTOR4
ClinGenLAMTOR4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD389541
Chemical/Pharm GKB GenePA162380687
Clinical trialLAMTOR4
Miscellaneous
canSAR (ICR)LAMTOR4 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAMTOR4
EVEXLAMTOR4
GoPubMedLAMTOR4
iHOPLAMTOR4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Nov 9 11:53:21 CET 2017

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