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LAMTOR5 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 5)

Identity

Alias (NCBI)HBXIP
XIP
HGNC (Hugo) LAMTOR5
HGNC Alias symbXIP
MGC71071
HGNC Alias nameHBx-interacting protein
 hepatitis B virus x-interacting protein (9.6kD)
HGNC Previous nameHBXIP
HGNC Previous namehepatitis B virus x interacting protein
LocusID (NCBI) 10542
Atlas_Id 47590
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 110401255 and ends at 110407924 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAMTOR5   17955
Cards
Entrez_Gene (NCBI)LAMTOR5  10542  late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
AliasesHBXIP; XIP
GeneCards (Weizmann)LAMTOR5
Ensembl hg19 (Hinxton)ENSG00000134248 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134248 [Gene_View]  ENSG00000134248 [Sequence]  chr1:110401255-110407924 [Contig_View]  LAMTOR5 [Vega]
ICGC DataPortalENSG00000134248
TCGA cBioPortalLAMTOR5
AceView (NCBI)LAMTOR5
Genatlas (Paris)LAMTOR5
WikiGenes10542
SOURCE (Princeton)LAMTOR5
Genetics Home Reference (NIH)LAMTOR5
Genomic and cartography
GoldenPath hg38 (UCSC)LAMTOR5  -     chr1:110401255-110407924 -  1p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LAMTOR5  -     1p13.3   [Description]    (hg19-Feb_2009)
GoldenPathLAMTOR5 - 1p13.3 [CytoView hg19]  LAMTOR5 - 1p13.3 [CytoView hg38]
ImmunoBaseENSG00000134248
genome Data Viewer NCBILAMTOR5 [Mapview hg19]  
OMIM608521   
Gene and transcription
Genbank (Entrez)AA443738 AF029890 AK054769 AK056679 AY623819
RefSeq transcript (Entrez)NM_001382293 NM_006402
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LAMTOR5
Alternative Splicing GalleryENSG00000134248
Gene ExpressionLAMTOR5 [ NCBI-GEO ]   LAMTOR5 [ EBI - ARRAY_EXPRESS ]   LAMTOR5 [ SEEK ]   LAMTOR5 [ MEM ]
Gene Expression Viewer (FireBrowse)LAMTOR5 [ Firebrowse - Broad ]
GenevisibleExpression of LAMTOR5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10542
GTEX Portal (Tissue expression)LAMTOR5
Human Protein AtlasENSG00000134248-LAMTOR5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43504   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43504  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43504
Splice isoforms : SwissVarO43504
PhosPhoSitePlusO43504
Domains : Interpro (EBI)LAMTOR5   
Domain families : Pfam (Sanger)LAMTOR5 (PF16672)   
Domain families : Pfam (NCBI)pfam16672   
Conserved Domain (NCBI)LAMTOR5
DMDM Disease mutations10542
Blocks (Seattle)LAMTOR5
PDB (RSDB)3MS6    3MSH    5VOK    5X6U    5X6V    5Y38    5Y39    5Y3A    5YK3    6EHP    6EHR    6NZD    6U62    6ULG   
PDB Europe3MS6    3MSH    5VOK    5X6U    5X6V    5Y38    5Y39    5Y3A    5YK3    6EHP    6EHR    6NZD    6U62    6ULG   
PDB (PDBSum)3MS6    3MSH    5VOK    5X6U    5X6V    5Y38    5Y39    5Y3A    5YK3    6EHP    6EHR    6NZD    6U62    6ULG   
PDB (IMB)3MS6    3MSH    5VOK    5X6U    5X6V    5Y38    5Y39    5Y3A    5YK3    6EHP    6EHR    6NZD    6U62    6ULG   
Structural Biology KnowledgeBase3MS6    3MSH    5VOK    5X6U    5X6V    5Y38    5Y39    5Y3A    5YK3    6EHP    6EHR    6NZD    6U62    6ULG   
SCOP (Structural Classification of Proteins)3MS6    3MSH    5VOK    5X6U    5X6V    5Y38    5Y39    5Y3A    5YK3    6EHP    6EHR    6NZD    6U62    6ULG   
CATH (Classification of proteins structures)3MS6    3MSH    5VOK    5X6U    5X6V    5Y38    5Y39    5Y3A    5YK3    6EHP    6EHR    6NZD    6U62    6ULG   
SuperfamilyO43504
Human Protein Atlas [tissue]ENSG00000134248-LAMTOR5 [tissue]
Peptide AtlasO43504
HPRD09773
IPIIPI00935729   IPI00976097   
Protein Interaction databases
DIP (DOE-UCLA)O43504
IntAct (EBI)O43504
FunCoupENSG00000134248
BioGRIDLAMTOR5
STRING (EMBL)LAMTOR5
ZODIACLAMTOR5
Ontologies - Pathways
QuickGOO43504
Ontology : AmiGOguanyl-nucleotide exchange factor activity  guanyl-nucleotide exchange factor activity  protein binding  lysosome  lysosome  lysosomal membrane  cytosol  cell cycle arrest  regulation of cell size  response to virus  positive regulation of gene expression  regulation of macroautophagy  viral genome replication  positive regulation of TOR signaling  negative regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  positive regulation of interleukin-8 biosynthetic process  positive regulation of NF-kappaB transcription factor activity  molecular adaptor activity  protein localization to lysosome  cellular response to amino acid stimulus  cellular response to amino acid stimulus  Ragulator complex  Ragulator complex  positive regulation of protein localization to nucleus  positive regulation of TORC1 signaling  positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  guanyl-nucleotide exchange factor activity  protein binding  lysosome  lysosome  lysosomal membrane  cytosol  cell cycle arrest  regulation of cell size  response to virus  positive regulation of gene expression  regulation of macroautophagy  viral genome replication  positive regulation of TOR signaling  negative regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  positive regulation of interleukin-8 biosynthetic process  positive regulation of NF-kappaB transcription factor activity  molecular adaptor activity  protein localization to lysosome  cellular response to amino acid stimulus  cellular response to amino acid stimulus  Ragulator complex  Ragulator complex  positive regulation of protein localization to nucleus  positive regulation of TORC1 signaling  positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding  
Pathways : KEGGHepatitis B   
NDEx NetworkLAMTOR5
Atlas of Cancer Signalling NetworkLAMTOR5
Wikipedia pathwaysLAMTOR5
Orthology - Evolution
OrthoDB10542
GeneTree (enSembl)ENSG00000134248
Phylogenetic Trees/Animal Genes : TreeFamLAMTOR5
HOGENOMO43504
Homologs : HomoloGeneLAMTOR5
Homology/Alignments : Family Browser (UCSC)LAMTOR5
Gene fusions - Rearrangements
Fusion : QuiverLAMTOR5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAMTOR5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAMTOR5
dbVarLAMTOR5
ClinVarLAMTOR5
1000_GenomesLAMTOR5 
Exome Variant ServerLAMTOR5
GNOMAD BrowserENSG00000134248
Varsome BrowserLAMTOR5
Genetic variants : HAPMAP10542
Genomic Variants (DGV)LAMTOR5 [DGVbeta]
DECIPHERLAMTOR5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLAMTOR5 
Mutations
ICGC Data PortalLAMTOR5 
TCGA Data PortalLAMTOR5 
Broad Tumor PortalLAMTOR5
OASIS PortalLAMTOR5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAMTOR5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLAMTOR5
Mutations and Diseases : HGMDLAMTOR5
BioMutasearch LAMTOR5
DgiDB (Drug Gene Interaction Database)LAMTOR5
DoCM (Curated mutations)LAMTOR5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAMTOR5 (select a term)
intoGenLAMTOR5
Cancer3DLAMTOR5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608521   
Orphanet
DisGeNETLAMTOR5
MedgenLAMTOR5
Genetic Testing Registry LAMTOR5
NextProtO43504 [Medical]
TSGene10542
GENETestsLAMTOR5
Target ValidationLAMTOR5
Huge Navigator LAMTOR5 [HugePedia]
snp3D : Map Gene to Disease10542
BioCentury BCIQLAMTOR5
ClinGenLAMTOR5
Clinical trials, drugs, therapy
Protein Interactions : CTD10542
Pharm GKB GenePA29211
Clinical trialLAMTOR5
Miscellaneous
canSAR (ICR)LAMTOR5 (select the gene name)
HarmonizomeLAMTOR5
DataMed IndexLAMTOR5
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAMTOR5
EVEXLAMTOR5
GoPubMedLAMTOR5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jul 16 15:19:52 CEST 2020

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