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LANCL1 (LanC like 1)

Identity

Alias (NCBI)GPR69A
p40
HGNC (Hugo) LANCL1
HGNC Alias symbp40
HGNC Previous nameGPR69A
HGNC Previous nameLanC (bacterial lantibiotic synthetase component C)-like 1
 LanC lantibiotic synthetase component C-like 1 (bacterial)
LocusID (NCBI) 10314
Atlas_Id 41125
Location 2q34  [Link to chromosome band 2q34]
Location_base_pair Starts at 210431251 and ends at 210476759 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKNAD1 (1p13.3) / LANCL1 (2q34)TET2 (4q24) / LANCL1 (2q34)TET2 4q24 / LANCL1 2q34

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LANCL1   6508
Cards
Entrez_Gene (NCBI)LANCL1    LanC like 1
AliasesGPR69A; p40
GeneCards (Weizmann)LANCL1
Ensembl hg19 (Hinxton)ENSG00000115365 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115365 [Gene_View]  ENSG00000115365 [Sequence]  chr2:210431251-210476759 [Contig_View]  LANCL1 [Vega]
ICGC DataPortalENSG00000115365
TCGA cBioPortalLANCL1
AceView (NCBI)LANCL1
Genatlas (Paris)LANCL1
SOURCE (Princeton)LANCL1
Genetics Home Reference (NIH)LANCL1
Genomic and cartography
GoldenPath hg38 (UCSC)LANCL1  -     chr2:210431251-210476759 -  2q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LANCL1  -     2q34   [Description]    (hg19-Feb_2009)
GoldenPathLANCL1 - 2q34 [CytoView hg19]  LANCL1 - 2q34 [CytoView hg38]
ImmunoBaseENSG00000115365
Genome Data Viewer NCBILANCL1 [Mapview hg19]  
OMIM604155   
Gene and transcription
Genbank (Entrez)AK294674 AK309295 AK312381 BC007041 BC028685
RefSeq transcript (Entrez)NM_001136574 NM_001136575 NM_006055
Consensus coding sequences : CCDS (NCBI)LANCL1
Gene ExpressionLANCL1 [ NCBI-GEO ]   LANCL1 [ EBI - ARRAY_EXPRESS ]   LANCL1 [ SEEK ]   LANCL1 [ MEM ]
Gene Expression Viewer (FireBrowse)LANCL1 [ Firebrowse - Broad ]
GenevisibleExpression of LANCL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10314
GTEX Portal (Tissue expression)LANCL1
Human Protein AtlasENSG00000115365-LANCL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43813   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43813  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43813
PhosPhoSitePlusO43813
Domains : Interpro (EBI)6hp_glycosidase-like_sf    LANC-like    LanC-like_prot_euk   
Domain families : Pfam (Sanger)LANC_like (PF05147)   
Domain families : Pfam (NCBI)pfam05147   
Domain families : Smart (EMBL)LANC_like (SM01260)  
Conserved Domain (NCBI)LANCL1
PDB (RSDB)3E6U    3E73   
PDB Europe3E6U    3E73   
PDB (PDBSum)3E6U    3E73   
PDB (IMB)3E6U    3E73   
Structural Biology KnowledgeBase3E6U    3E73   
SCOP (Structural Classification of Proteins)3E6U    3E73   
CATH (Classification of proteins structures)3E6U    3E73   
SuperfamilyO43813
AlphaFold pdb e-kbO43813   
Human Protein Atlas [tissue]ENSG00000115365-LANCL1 [tissue]
HPRD16040
Protein Interaction databases
DIP (DOE-UCLA)O43813
IntAct (EBI)O43813
BioGRIDLANCL1
STRING (EMBL)LANCL1
ZODIACLANCL1
Ontologies - Pathways
QuickGOO43813
Ontology : AmiGOglutathione transferase activity  G protein-coupled receptor activity  protein binding  cytoplasm  plasma membrane  integral component of plasma membrane  carbohydrate metabolic process  G protein-coupled receptor signaling pathway  zinc ion binding  SH3 domain binding  glutathione binding  regulation of neuron apoptotic process  low-density lipoprotein particle receptor binding  regulation of oxidative stress-induced neuron death  
Ontology : EGO-EBIglutathione transferase activity  G protein-coupled receptor activity  protein binding  cytoplasm  plasma membrane  integral component of plasma membrane  carbohydrate metabolic process  G protein-coupled receptor signaling pathway  zinc ion binding  SH3 domain binding  glutathione binding  regulation of neuron apoptotic process  low-density lipoprotein particle receptor binding  regulation of oxidative stress-induced neuron death  
NDEx NetworkLANCL1
Atlas of Cancer Signalling NetworkLANCL1
Wikipedia pathwaysLANCL1
Orthology - Evolution
OrthoDB10314
GeneTree (enSembl)ENSG00000115365
Phylogenetic Trees/Animal Genes : TreeFamLANCL1
Homologs : HomoloGeneLANCL1
Homology/Alignments : Family Browser (UCSC)LANCL1
Gene fusions - Rearrangements
Fusion : QuiverLANCL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLANCL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LANCL1
dbVarLANCL1
ClinVarLANCL1
MonarchLANCL1
1000_GenomesLANCL1 
Exome Variant ServerLANCL1
GNOMAD BrowserENSG00000115365
Varsome BrowserLANCL1
ACMGLANCL1 variants
VarityO43813
Genomic Variants (DGV)LANCL1 [DGVbeta]
DECIPHERLANCL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLANCL1 
Mutations
ICGC Data PortalLANCL1 
TCGA Data PortalLANCL1 
Broad Tumor PortalLANCL1
OASIS PortalLANCL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLANCL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLANCL1
Mutations and Diseases : HGMDLANCL1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLANCL1
DgiDB (Drug Gene Interaction Database)LANCL1
DoCM (Curated mutations)LANCL1
CIViC (Clinical Interpretations of Variants in Cancer)LANCL1
Cancer3DLANCL1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604155   
Orphanet
DisGeNETLANCL1
MedgenLANCL1
Genetic Testing Registry LANCL1
NextProtO43813 [Medical]
GENETestsLANCL1
Target ValidationLANCL1
Huge Navigator LANCL1 [HugePedia]
ClinGenLANCL1
Clinical trials, drugs, therapy
MyCancerGenomeLANCL1
Protein Interactions : CTDLANCL1
Pharm GKB GenePA30293
PharosO43813
Clinical trialLANCL1
Miscellaneous
canSAR (ICR)LANCL1
HarmonizomeLANCL1
DataMed IndexLANCL1
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLANCL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:15:34 CEST 2021

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