Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LANCL2 (LanC like 2)

Identity

Alias (NCBI)GPR69B
TASP
HGNC (Hugo) LANCL2
HGNC Alias symbTASP
HGNC Alias nametestis-specific adriamycin sensitivity protein
 G protein-coupled receptor 69B
HGNC Previous nameGPR69B
HGNC Previous nameLanC (bacterial lantibiotic synthetase component C)-like 2
 LanC lantibiotic synthetase component C-like 2 (bacterial)
LocusID (NCBI) 55915
Atlas_Id 54418
Location 7p11.2  [Link to chromosome band 7p11]
Location_base_pair Starts at 55365448 and ends at 55433742 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BRDT (1p22.1) / LANCL2 (7p11.2)LANCL2 (7p11.2) / LANCL2 (7p11.2)LANCL2 (7p11.2) / PSPH (7p11.2)
LANCL2 (7p11.2) / SEPT14 (7p11.2)LANCL2 (7p11.2) / TFDP2 (3q23)RP11-15K19.2 () / LANCL2 (7p11.2)
TFDP2 (3q23) / LANCL2 (7p11.2)ZNF786 (7q36.1) / LANCL2 (7p11.2)LANCL2 7p11.2 / SEPT14 7p11.2
LANCL2 7p11.2 / TFDP2 3q23RP11-15K19.2 LANCL2 7p11.2TFDP2 3q23 / LANCL2 7p11.2
ZNF786 7q36.1 / LANCL2 7p11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LANCL2   6509
Cards
Entrez_Gene (NCBI)LANCL2    LanC like 2
AliasesGPR69B; TASP
GeneCards (Weizmann)LANCL2
Ensembl hg19 (Hinxton)ENSG00000132434 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132434 [Gene_View]  ENSG00000132434 [Sequence]  chr7:55365448-55433742 [Contig_View]  LANCL2 [Vega]
ICGC DataPortalENSG00000132434
TCGA cBioPortalLANCL2
AceView (NCBI)LANCL2
Genatlas (Paris)LANCL2
SOURCE (Princeton)LANCL2
Genetics Home Reference (NIH)LANCL2
Genomic and cartography
GoldenPath hg38 (UCSC)LANCL2  -     chr7:55365448-55433742 +  7p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LANCL2  -     7p11.2   [Description]    (hg19-Feb_2009)
GoldenPathLANCL2 - 7p11.2 [CytoView hg19]  LANCL2 - 7p11.2 [CytoView hg38]
ImmunoBaseENSG00000132434
Genome Data Viewer NCBILANCL2 [Mapview hg19]  
OMIM612919   
Gene and transcription
Genbank (Entrez)AA994905 AB035966 AF353942 AJ278245 AK095857
RefSeq transcript (Entrez)NM_018697
Consensus coding sequences : CCDS (NCBI)LANCL2
Gene ExpressionLANCL2 [ NCBI-GEO ]   LANCL2 [ EBI - ARRAY_EXPRESS ]   LANCL2 [ SEEK ]   LANCL2 [ MEM ]
Gene Expression Viewer (FireBrowse)LANCL2 [ Firebrowse - Broad ]
GenevisibleExpression of LANCL2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55915
GTEX Portal (Tissue expression)LANCL2
Human Protein AtlasENSG00000132434-LANCL2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS86   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS86  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS86
PhosPhoSitePlusQ9NS86
Domains : Interpro (EBI)6hp_glycosidase-like_sf    LANC-like    LanC-like_prot_euk   
Domain families : Pfam (Sanger)LANC_like (PF05147)   
Domain families : Pfam (NCBI)pfam05147   
Domain families : Smart (EMBL)LANC_like (SM01260)  
Conserved Domain (NCBI)LANCL2
SuperfamilyQ9NS86
AlphaFold pdb e-kbQ9NS86   
Human Protein Atlas [tissue]ENSG00000132434-LANCL2 [tissue]
HPRD13956
Protein Interaction databases
DIP (DOE-UCLA)Q9NS86
IntAct (EBI)Q9NS86
BioGRIDLANCL2
STRING (EMBL)LANCL2
ZODIACLANCL2
Ontologies - Pathways
QuickGOQ9NS86
Ontology : AmiGOprotein binding  ATP binding  GTP binding  nucleus  nucleus  nucleoplasm  cytosol  plasma membrane  plasma membrane  carbohydrate metabolic process  positive regulation of abscisic acid-activated signaling pathway  phosphatidylinositol-5-phosphate binding  cortical actin cytoskeleton  phosphatidylinositol-3-phosphate binding  negative regulation of transcription, DNA-templated  phosphatidylinositol-4-phosphate binding  
Ontology : EGO-EBIprotein binding  ATP binding  GTP binding  nucleus  nucleus  nucleoplasm  cytosol  plasma membrane  plasma membrane  carbohydrate metabolic process  positive regulation of abscisic acid-activated signaling pathway  phosphatidylinositol-5-phosphate binding  cortical actin cytoskeleton  phosphatidylinositol-3-phosphate binding  negative regulation of transcription, DNA-templated  phosphatidylinositol-4-phosphate binding  
NDEx NetworkLANCL2
Atlas of Cancer Signalling NetworkLANCL2
Wikipedia pathwaysLANCL2
Orthology - Evolution
OrthoDB55915
GeneTree (enSembl)ENSG00000132434
Phylogenetic Trees/Animal Genes : TreeFamLANCL2
Homologs : HomoloGeneLANCL2
Homology/Alignments : Family Browser (UCSC)LANCL2
Gene fusions - Rearrangements
Fusion : MitelmanLANCL2/PSPH [7p11.2/7p11.2]  
Fusion : MitelmanLANCL2/SEPT14 [7p11.2/7p11.2]  
Fusion : MitelmanLANCL2/TFDP2 [7p11.2/3q23]  
Fusion : MitelmanTFDP2/LANCL2 [3q23/7p11.2]  
Fusion : MitelmanZNF786/LANCL2 [7q36.1/7p11.2]  
Fusion : QuiverLANCL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLANCL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LANCL2
dbVarLANCL2
ClinVarLANCL2
MonarchLANCL2
1000_GenomesLANCL2 
Exome Variant ServerLANCL2
GNOMAD BrowserENSG00000132434
Varsome BrowserLANCL2
ACMGLANCL2 variants
VarityQ9NS86
Genomic Variants (DGV)LANCL2 [DGVbeta]
DECIPHERLANCL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLANCL2 
Mutations
ICGC Data PortalLANCL2 
TCGA Data PortalLANCL2 
Broad Tumor PortalLANCL2
OASIS PortalLANCL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLANCL2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLANCL2
Mutations and Diseases : HGMDLANCL2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLANCL2
DgiDB (Drug Gene Interaction Database)LANCL2
DoCM (Curated mutations)LANCL2
CIViC (Clinical Interpretations of Variants in Cancer)LANCL2
Cancer3DLANCL2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612919   
Orphanet
DisGeNETLANCL2
MedgenLANCL2
Genetic Testing Registry LANCL2
NextProtQ9NS86 [Medical]
GENETestsLANCL2
Target ValidationLANCL2
Huge Navigator LANCL2 [HugePedia]
ClinGenLANCL2
Clinical trials, drugs, therapy
MyCancerGenomeLANCL2
Protein Interactions : CTDLANCL2
Pharm GKB GenePA30294
PharosQ9NS86
Clinical trialLANCL2
Miscellaneous
canSAR (ICR)LANCL2
HarmonizomeLANCL2
DataMed IndexLANCL2
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLANCL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:15:35 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.