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LANCL2 (LanC like 2)

Identity

Alias_namesGPR69B
LanC (bacterial lantibiotic synthetase component C)-like 2
LanC lantibiotic synthetase component C-like 2 (bacterial)
Alias_symbol (synonym)TASP
Other alias
HGNC (Hugo) LANCL2
LocusID (NCBI) 55915
Atlas_Id 54418
Location 7p11.2  [Link to chromosome band 7p11]
Location_base_pair Starts at 55365448 and ends at 55433742 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BRDT (1p22.1) / LANCL2 (7p11.2)LANCL2 (7p11.2) / LANCL2 (7p11.2)LANCL2 (7p11.2) / PSPH (7p11.2)
LANCL2 (7p11.2) / SEPT14 (7p11.2)LANCL2 (7p11.2) / TFDP2 (3q23)RP11-15K19.2 () / LANCL2 (7p11.2)
TFDP2 (3q23) / LANCL2 (7p11.2)ZNF786 (7q36.1) / LANCL2 (7p11.2)LANCL2 7p11.2 / SEPT14 7p11.2
LANCL2 7p11.2 / TFDP2 3q23RP11-15K19.2 LANCL2 7p11.2TFDP2 3q23 / LANCL2 7p11.2
ZNF786 7q36.1 / LANCL2 7p11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LANCL2   6509
Cards
Entrez_Gene (NCBI)LANCL2  55915  LanC like 2
AliasesGPR69B; TASP
GeneCards (Weizmann)LANCL2
Ensembl hg19 (Hinxton)ENSG00000132434 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132434 [Gene_View]  chr7:55365448-55433742 [Contig_View]  LANCL2 [Vega]
ICGC DataPortalENSG00000132434
TCGA cBioPortalLANCL2
AceView (NCBI)LANCL2
Genatlas (Paris)LANCL2
WikiGenes55915
SOURCE (Princeton)LANCL2
Genetics Home Reference (NIH)LANCL2
Genomic and cartography
GoldenPath hg38 (UCSC)LANCL2  -     chr7:55365448-55433742 +  7p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LANCL2  -     7p11.2   [Description]    (hg19-Feb_2009)
EnsemblLANCL2 - 7p11.2 [CytoView hg19]  LANCL2 - 7p11.2 [CytoView hg38]
Mapping of homologs : NCBILANCL2 [Mapview hg19]  LANCL2 [Mapview hg38]
OMIM612919   
Gene and transcription
Genbank (Entrez)AA994905 AB035966 AF353942 AJ278245 AK095857
RefSeq transcript (Entrez)NM_018697
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LANCL2
Cluster EST : UnigeneHs.706612 [ NCBI ]
CGAP (NCI)Hs.706612
Alternative Splicing GalleryENSG00000132434
Gene ExpressionLANCL2 [ NCBI-GEO ]   LANCL2 [ EBI - ARRAY_EXPRESS ]   LANCL2 [ SEEK ]   LANCL2 [ MEM ]
Gene Expression Viewer (FireBrowse)LANCL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55915
GTEX Portal (Tissue expression)LANCL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS86   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS86  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS86
Splice isoforms : SwissVarQ9NS86
PhosPhoSitePlusQ9NS86
Domains : Interpro (EBI)6hp_glycosidase    LANC-like    LanC-like_prot_euk   
Domain families : Pfam (Sanger)LANC_like (PF05147)   
Domain families : Pfam (NCBI)pfam05147   
Domain families : Smart (EMBL)LANC_like (SM01260)  
Conserved Domain (NCBI)LANCL2
DMDM Disease mutations55915
Blocks (Seattle)LANCL2
SuperfamilyQ9NS86
Human Protein AtlasENSG00000132434
Peptide AtlasQ9NS86
HPRD13956
IPIIPI00032995   IPI00925775   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS86
IntAct (EBI)Q9NS86
FunCoupENSG00000132434
BioGRIDLANCL2
STRING (EMBL)LANCL2
ZODIACLANCL2
Ontologies - Pathways
QuickGOQ9NS86
Ontology : AmiGOprotein binding  ATP binding  GTP binding  nucleus  cytosol  plasma membrane  positive regulation of abscisic acid-activated signaling pathway  phosphatidylinositol-5-phosphate binding  cortical actin cytoskeleton  phosphatidylinositol-3-phosphate binding  negative regulation of transcription, DNA-templated  phosphatidylinositol-4-phosphate binding  
Ontology : EGO-EBIprotein binding  ATP binding  GTP binding  nucleus  cytosol  plasma membrane  positive regulation of abscisic acid-activated signaling pathway  phosphatidylinositol-5-phosphate binding  cortical actin cytoskeleton  phosphatidylinositol-3-phosphate binding  negative regulation of transcription, DNA-templated  phosphatidylinositol-4-phosphate binding  
NDEx NetworkLANCL2
Atlas of Cancer Signalling NetworkLANCL2
Wikipedia pathwaysLANCL2
Orthology - Evolution
OrthoDB55915
GeneTree (enSembl)ENSG00000132434
Phylogenetic Trees/Animal Genes : TreeFamLANCL2
HOVERGENQ9NS86
HOGENOMQ9NS86
Homologs : HomoloGeneLANCL2
Homology/Alignments : Family Browser (UCSC)LANCL2
Gene fusions - Rearrangements
Fusion : MitelmanLANCL2/PSPH [7p11.2/7p11.2]  
Fusion : MitelmanLANCL2/SEPT14 [7p11.2/7p11.2]  [t(7;7)(p11;p11)]  
Fusion : MitelmanLANCL2/TFDP2 [7p11.2/3q23]  [t(3;7)(q23;p11)]  
Fusion : MitelmanTFDP2/LANCL2 [3q23/7p11.2]  [t(3;7)(q23;p11)]  
Fusion : MitelmanZNF786/LANCL2 [7q36.1/7p11.2]  [t(7;7)(p11;q36)]  
Fusion: TCGALANCL2 7p11.2 SEPT14 7p11.2 GBM
Fusion: TCGALANCL2 7p11.2 TFDP2 3q23 BRCA
Fusion: TCGARP11-15K19.2 LANCL2 7p11.2 GBM
Fusion: TCGATFDP2 3q23 LANCL2 7p11.2 BRCA
Fusion: TCGAZNF786 7q36.1 LANCL2 7p11.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLANCL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LANCL2
dbVarLANCL2
ClinVarLANCL2
1000_GenomesLANCL2 
Exome Variant ServerLANCL2
ExAC (Exome Aggregation Consortium)LANCL2 (select the gene name)
Genetic variants : HAPMAP55915
Genomic Variants (DGV)LANCL2 [DGVbeta]
DECIPHERLANCL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLANCL2 
Mutations
ICGC Data PortalLANCL2 
TCGA Data PortalLANCL2 
Broad Tumor PortalLANCL2
OASIS PortalLANCL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLANCL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLANCL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LANCL2
DgiDB (Drug Gene Interaction Database)LANCL2
DoCM (Curated mutations)LANCL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LANCL2 (select a term)
intoGenLANCL2
Cancer3DLANCL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612919   
Orphanet
MedgenLANCL2
Genetic Testing Registry LANCL2
NextProtQ9NS86 [Medical]
TSGene55915
GENETestsLANCL2
Target ValidationLANCL2
Huge Navigator LANCL2 [HugePedia]
snp3D : Map Gene to Disease55915
BioCentury BCIQLANCL2
ClinGenLANCL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55915
Chemical/Pharm GKB GenePA30294
Clinical trialLANCL2
Miscellaneous
canSAR (ICR)LANCL2 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLANCL2
EVEXLANCL2
GoPubMedLANCL2
iHOPLANCL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:40:13 CEST 2017

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