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LAPTM5 (lysosomal protein transmembrane 5)

Identity

Alias_nameslysosomal multispanning membrane protein 5
Other aliasCLAST6
HGNC (Hugo) LAPTM5
LocusID (NCBI) 7805
Atlas_Id 53018
Location 1p35.2  [Link to chromosome band 1p35]
Location_base_pair Starts at 30732468 and ends at 30757836 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LAPTM5 (1p35.2) / AFAP1L1 (5q32)LAPTM5 (1p35.2) / CD82 (11p11.2)LAPTM5 (1p35.2) / GRID2IP (7p22.1)
LAPTM5 (1p35.2) / JADE3 (Xp11.23)LAPTM5 (1p35.2) / POR (7q11.23)LAPTM5 (1p35.2) / ZBTB20 (3q13.31)
MFSD2A (1p34.2) / LAPTM5 (1p35.2)SNORA63 (3q27.3) / LAPTM5 (1p35.2)MFSD2A 1p34.2 / LAPTM5 1p35.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAPTM5   29612
Cards
Entrez_Gene (NCBI)LAPTM5  7805  lysosomal protein transmembrane 5
AliasesCLAST6
GeneCards (Weizmann)LAPTM5
Ensembl hg19 (Hinxton)ENSG00000162511 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162511 [Gene_View]  chr1:30732468-30757836 [Contig_View]  LAPTM5 [Vega]
ICGC DataPortalENSG00000162511
TCGA cBioPortalLAPTM5
AceView (NCBI)LAPTM5
Genatlas (Paris)LAPTM5
WikiGenes7805
SOURCE (Princeton)LAPTM5
Genetics Home Reference (NIH)LAPTM5
Genomic and #artoGraqhy
GoldenPath hg38 (UCSC)LAPTM5  -     chr1:30732468-30757836 -  1p35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LAPTM5  -     1p35.2   [Description]    (hg19-Feb_2009)
EnsemblLAPTM5 - 1p35.2 [CytoView hg19]  LAPTM5 - 1p35.2 [CytoView hg38]
Mapping of homologs : NCBILAPTM5 [Mapview hg19]  LAPTM5 [Mapview hg38]
OMIM601476   
Gene and transcription
Genbank (Entrez)AF401210 AK292009 AK297014 BC106896 BC106897
RefSeq transcript (Entrez)NM_006762
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LAPTM5
Cluster EST : UnigeneHs.371021 [ NCBI ]
CGAP (NCI)Hs.371021
Alternative Splicing GalleryENSG00000162511
Gene ExpressionLAPTM5 [ NCBI-GEO ]   LAPTM5 [ EBI - ARRAY_EXPRESS ]   LAPTM5 [ SEEK ]   LAPTM5 [ MEM ]
Gene Expression Viewer (FireBrowse)LAPTM5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7805
GTEX Portal (Tissue expression)LAPTM5
Human Protein AtlasENSG00000162511-LAPTM5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13571   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13571  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13571
Splice isoforms : SwissVarQ13571
PhosPhoSitePlusQ13571
Domains : Interpro (EBI)LAPTM4/5    LAPTM_4A/5    Lysosomal-assoc_TM_prot5   
Domain families : Pfam (Sanger)Mtp (PF03821)   
Domain families : Pfam (NCBI)pfam03821   
Conserved Domain (NCBI)LAPTM5
DMDM Disease mutations7805
Blocks (Seattle)LAPTM5
SuperfamilyQ13571
Human Protein Atlas [tissue]ENSG00000162511-LAPTM5 [tissue]
Peptide AtlasQ13571
HPRD03280
IPIIPI00013827   IPI00910991   
Protein Interaction databases
DIP (DOE-UCLA)Q13571
IntAct (EBI)Q13571
FunCoupENSG00000162511
BioGRIDLAPTM5
STRING (EMBL)LAPTM5
ZODIACLAPTM5
Ontologies - Pathways
QuickGOQ13571
Ontology : AmiGOprotein binding  lysosome  lysosomal membrane  integral component of plasma membrane  transport  
Ontology : EGO-EBIprotein binding  lysosome  lysosomal membrane  integral component of plasma membrane  transport  
Pathways : KEGGLysosome   
NDEx NetworkLAPTM5
Atlas of Cancer Signalling NetworkLAPTM5
Wikipedia pathwaysLAPTM5
Orthology - Evolution
OrthoDB7805
GeneTree (enSembl)ENSG00000162511
Phylogenetic Trees/Animal Genes : TreeFamLAPTM5
HOVERGENQ13571
HOGENOMQ13571
Homologs : HomoloGeneLAPTM5
Homology/Alignments : Family Browser (UCSC)LAPTM5
Gene fusions - Rearrangements
Fusion : MitelmanMFSD2A/LAPTM5 [1p34.2/1p35.2]  [t(1;1)(p34;p35)]  
Fusion: TCGAMFSD2A 1p34.2 LAPTM5 1p35.2 LGG
Fusion: Tumor Portal LAPTM5
Fusion Cancer (Beijing)LAPTM5 [1p35.2]  -  GRID2IP [7p22.1]  [FUSC002423]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAPTM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAPTM5
dbVarLAPTM5
ClinVarLAPTM5
1000_GenomesLAPTM5 
Exome Variant ServerLAPTM5
ExAC (Exome Aggregation Consortium)ENSG00000162511
GNOMAD BrowserENSG00000162511
Genetic variants : HAPMAP7805
Genomic Variants (DGV)LAPTM5 [DGVbeta]
DECIPHERLAPTM5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLAPTM5 
Mutations
ICGC Data PortalLAPTM5 
TCGA Data PortalLAPTM5 
Broad Tumor PortalLAPTM5
OASIS PortalLAPTM5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAPTM5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLAPTM5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LAPTM5
DgiDB (Drug Gene Interaction Database)LAPTM5
DoCM (Curated mutations)LAPTM5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAPTM5 (select a term)
intoGenLAPTM5
Cancer3DLAPTM5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601476   
Orphanet
MedgenLAPTM5
Genetic Testing Registry LAPTM5
NextProtQ13571 [Medical]
TSGene7805
GENETestsLAPTM5
Target ValidationLAPTM5
Huge Navigator LAPTM5 [HugePedia]
snp3D : Map Gene to Disease7805
BioCentury BCIQLAPTM5
ClinGenLAPTM5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7805
Chemical/Pharm GKB GenePA134953439
Clinical trialLAPTM5
Miscellaneous
canSAR (ICR)LAPTM5 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAPTM5
EVEXLAPTM5
GoPubMedLAPTM5
iHOPLAPTM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:56:04 CET 2017

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