Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LARP1 (La ribonucleoprotein domain family member 1)

Identity

Alias_namesLa ribonucleoprotein domain family
Alias_symbol (synonym)LARP
KIAA0731
MGC19556
Other alias
HGNC (Hugo) LARP1
LocusID (NCBI) 23367
Atlas_Id 55577
Location 5q33.2  [Link to chromosome band 5q33]
Location_base_pair Starts at 154712902 and ends at 154817607 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EPB41L2 (6q23.1) / LARP1 (5q33.2)EPT1 (2p23.3) / LARP1 (5q33.2)FAM84A (2p24.3) / LARP1 (5q33.2)
LARP1 (5q33.2) / ANKLE2 (12q24.33)LARP1 (5q33.2) / HIRA (22q11.21)LARP1 (5q33.2) / LARP1 (5q33.2)
LARP1 (5q33.2) / PAPPA (9q33.1)SAMD14 (17q21.33) / LARP1 (5q33.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LARP1   29531
Cards
Entrez_Gene (NCBI)LARP1  23367  La ribonucleoprotein domain family member 1
AliasesLARP
GeneCards (Weizmann)LARP1
Ensembl hg19 (Hinxton)ENSG00000155506 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155506 [Gene_View]  chr5:154712902-154817607 [Contig_View]  LARP1 [Vega]
ICGC DataPortalENSG00000155506
TCGA cBioPortalLARP1
AceView (NCBI)LARP1
Genatlas (Paris)LARP1
WikiGenes23367
SOURCE (Princeton)LARP1
Genetics Home Reference (NIH)LARP1
Genomic and cartography
GoldenPath hg38 (UCSC)LARP1  -     chr5:154712902-154817607 +  5q33.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LARP1  -     5q33.2   [Description]    (hg19-Feb_2009)
EnsemblLARP1 - 5q33.2 [CytoView hg19]  LARP1 - 5q33.2 [CytoView hg38]
Mapping of homologs : NCBILARP1 [Mapview hg19]  LARP1 [Mapview hg38]
OMIM612059   
Gene and transcription
Genbank (Entrez)AB018274 AK091465 AK307554 AK312203 AL133034
RefSeq transcript (Entrez)NM_015315 NM_033551
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LARP1
Cluster EST : UnigeneHs.292078 [ NCBI ]
CGAP (NCI)Hs.292078
Alternative Splicing GalleryENSG00000155506
Gene ExpressionLARP1 [ NCBI-GEO ]   LARP1 [ EBI - ARRAY_EXPRESS ]   LARP1 [ SEEK ]   LARP1 [ MEM ]
Gene Expression Viewer (FireBrowse)LARP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23367
GTEX Portal (Tissue expression)LARP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PKG0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PKG0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PKG0
Splice isoforms : SwissVarQ6PKG0
PhosPhoSitePlusQ6PKG0
Domaine pattern : Prosite (Expaxy)HTH_LA (PS50961)   
Domains : Interpro (EBI)DM15    Lupus_La_RNA-bd    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)La (PF05383)   
Domain families : Pfam (NCBI)pfam05383   
Domain families : Smart (EMBL)DM15 (SM00684)  LA (SM00715)  
Conserved Domain (NCBI)LARP1
DMDM Disease mutations23367
Blocks (Seattle)LARP1
PDB (SRS)4ZC4    5C0V   
PDB (PDBSum)4ZC4    5C0V   
PDB (IMB)4ZC4    5C0V   
PDB (RSDB)4ZC4    5C0V   
Structural Biology KnowledgeBase4ZC4    5C0V   
SCOP (Structural Classification of Proteins)4ZC4    5C0V   
CATH (Classification of proteins structures)4ZC4    5C0V   
SuperfamilyQ6PKG0
Human Protein AtlasENSG00000155506
Peptide AtlasQ6PKG0
HPRD11225
IPIIPI00185919   IPI00411690   IPI00978705   IPI00979999   IPI00981350   IPI00979406   IPI00977919   IPI00976553   IPI00981989   IPI00985284   IPI00975979   IPI00977280   
Protein Interaction databases
DIP (DOE-UCLA)Q6PKG0
IntAct (EBI)Q6PKG0
FunCoupENSG00000155506
BioGRIDLARP1
STRING (EMBL)LARP1
ZODIACLARP1
Ontologies - Pathways
QuickGOQ6PKG0
Ontology : AmiGORNA cap binding  RNA binding  mRNA 3'-UTR binding  protein binding  cytoplasm  polysome  translational initiation  eukaryotic initiation factor 4E binding  cell proliferation  translation activator activity  cytoplasmic stress granule  membrane  positive regulation of macroautophagy  negative regulation of translation  translation initiation factor binding  TOR signaling  TORC1 complex  TORC1 signaling  positive regulation of viral genome replication  cadherin binding  positive regulation of translation  mRNA 5'-UTR binding  mRNA 5'-UTR binding  mRNA stabilization  cellular response to rapamycin  response to amino acid starvation  
Ontology : EGO-EBIRNA cap binding  RNA binding  mRNA 3'-UTR binding  protein binding  cytoplasm  polysome  translational initiation  eukaryotic initiation factor 4E binding  cell proliferation  translation activator activity  cytoplasmic stress granule  membrane  positive regulation of macroautophagy  negative regulation of translation  translation initiation factor binding  TOR signaling  TORC1 complex  TORC1 signaling  positive regulation of viral genome replication  cadherin binding  positive regulation of translation  mRNA 5'-UTR binding  mRNA 5'-UTR binding  mRNA stabilization  cellular response to rapamycin  response to amino acid starvation  
NDEx NetworkLARP1
Atlas of Cancer Signalling NetworkLARP1
Wikipedia pathwaysLARP1
Orthology - Evolution
OrthoDB23367
GeneTree (enSembl)ENSG00000155506
Phylogenetic Trees/Animal Genes : TreeFamLARP1
HOVERGENQ6PKG0
HOGENOMQ6PKG0
Homologs : HomoloGeneLARP1
Homology/Alignments : Family Browser (UCSC)LARP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLARP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LARP1
dbVarLARP1
ClinVarLARP1
1000_GenomesLARP1 
Exome Variant ServerLARP1
ExAC (Exome Aggregation Consortium)LARP1 (select the gene name)
Genetic variants : HAPMAP23367
Genomic Variants (DGV)LARP1 [DGVbeta]
DECIPHERLARP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLARP1 
Mutations
ICGC Data PortalLARP1 
TCGA Data PortalLARP1 
Broad Tumor PortalLARP1
OASIS PortalLARP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLARP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLARP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LARP1
DgiDB (Drug Gene Interaction Database)LARP1
DoCM (Curated mutations)LARP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LARP1 (select a term)
intoGenLARP1
Cancer3DLARP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612059   
Orphanet
MedgenLARP1
Genetic Testing Registry LARP1
NextProtQ6PKG0 [Medical]
TSGene23367
GENETestsLARP1
Target ValidationLARP1
Huge Navigator LARP1 [HugePedia]
snp3D : Map Gene to Disease23367
BioCentury BCIQLARP1
ClinGenLARP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23367
Chemical/Pharm GKB GenePA142671564
Clinical trialLARP1
Miscellaneous
canSAR (ICR)LARP1 (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLARP1
EVEXLARP1
GoPubMedLARP1
iHOPLARP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:40:14 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.