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LARP4B (La ribonucleoprotein 4B)

Identity

Alias (NCBI)KIAA0217
LARP5
HGNC (Hugo) LARP4B
HGNC Previous nameKIAA0217
 LARP5
HGNC Previous nameKIAA0217
 La ribonucleoprotein domain family, member 5
 La ribonucleoprotein domain family, member 4B
 La ribonucleoprotein domain family member 4B
LocusID (NCBI) 23185
Atlas_Id 56893
Location 10p15.3  [Link to chromosome band 10p15]
Location_base_pair Starts at 809497 and ends at 931705 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCND3 (6p21.1) / LARP4B (10p15.3)JUN (1p32.1) / LARP4B (10p15.3)LARP4B (10p15.3) / LARP4B (10p15.3)
LARP4B (10p15.3) / PFKFB3 (10p15.1)LARP4B (10p15.3) / SMCO3 (12p12.3)LARP4B (10p15.3) / STAM2 (2q23.3)
LARP4B (10p15.3) / TSPAN33 (7q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LARP4B   28987
Cards
Entrez_Gene (NCBI)LARP4B    La ribonucleoprotein 4B
AliasesKIAA0217; LARP5
GeneCards (Weizmann)LARP4B
Ensembl hg19 (Hinxton)ENSG00000107929 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107929 [Gene_View]  ENSG00000107929 [Sequence]  chr10:809497-931705 [Contig_View]  LARP4B [Vega]
ICGC DataPortalENSG00000107929
TCGA cBioPortalLARP4B
AceView (NCBI)LARP4B
Genatlas (Paris)LARP4B
SOURCE (Princeton)LARP4B
Genetics Home Reference (NIH)LARP4B
Genomic and cartography
GoldenPath hg38 (UCSC)LARP4B  -     chr10:809497-931705 -  10p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LARP4B  -     10p15.3   [Description]    (hg19-Feb_2009)
GoldenPathLARP4B - 10p15.3 [CytoView hg19]  LARP4B - 10p15.3 [CytoView hg38]
ImmunoBaseENSG00000107929
Genome Data Viewer NCBILARP4B [Mapview hg19]  
OMIM616513   
Gene and transcription
Genbank (Entrez)AK126769 AU132926 BC003381 BC131630 BC152443
RefSeq transcript (Entrez)NM_001351277 NM_015155
Consensus coding sequences : CCDS (NCBI)LARP4B
Gene ExpressionLARP4B [ NCBI-GEO ]   LARP4B [ EBI - ARRAY_EXPRESS ]   LARP4B [ SEEK ]   LARP4B [ MEM ]
Gene Expression Viewer (FireBrowse)LARP4B [ Firebrowse - Broad ]
GenevisibleExpression of LARP4B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23185
GTEX Portal (Tissue expression)LARP4B
Human Protein AtlasENSG00000107929-LARP4B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92615   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92615  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92615
PhosPhoSitePlusQ92615
Domaine pattern : Prosite (Expaxy)HTH_LA (PS50961)   
Domains : Interpro (EBI)La_HTH    LARP5_RRM    RBD_domain_sf    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)La (PF05383)   
Domain families : Pfam (NCBI)pfam05383   
Domain families : Smart (EMBL)LA (SM00715)  
Conserved Domain (NCBI)LARP4B
PDB (RSDB)3PTH   
PDB Europe3PTH   
PDB (PDBSum)3PTH   
PDB (IMB)3PTH   
Structural Biology KnowledgeBase3PTH   
SCOP (Structural Classification of Proteins)3PTH   
CATH (Classification of proteins structures)3PTH   
SuperfamilyQ92615
AlphaFold pdb e-kbQ92615   
Human Protein Atlas [tissue]ENSG00000107929-LARP4B [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q92615
IntAct (EBI)Q92615
BioGRIDLARP4B
STRING (EMBL)LARP4B
ZODIACLARP4B
Ontologies - Pathways
QuickGOQ92615
Ontology : AmiGORNA binding  mRNA 3'-UTR binding  protein binding  nucleolus  cytosol  cytoplasmic stress granule  membrane  polysomal ribosome  positive regulation of translation  positive regulation of 3'-UTR-mediated mRNA stabilization  
Ontology : EGO-EBIRNA binding  mRNA 3'-UTR binding  protein binding  nucleolus  cytosol  cytoplasmic stress granule  membrane  polysomal ribosome  positive regulation of translation  positive regulation of 3'-UTR-mediated mRNA stabilization  
NDEx NetworkLARP4B
Atlas of Cancer Signalling NetworkLARP4B
Wikipedia pathwaysLARP4B
Orthology - Evolution
OrthoDB23185
GeneTree (enSembl)ENSG00000107929
Phylogenetic Trees/Animal Genes : TreeFamLARP4B
Homologs : HomoloGeneLARP4B
Homology/Alignments : Family Browser (UCSC)LARP4B
Gene fusions - Rearrangements
Fusion : QuiverLARP4B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLARP4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LARP4B
dbVarLARP4B
ClinVarLARP4B
MonarchLARP4B
1000_GenomesLARP4B 
Exome Variant ServerLARP4B
GNOMAD BrowserENSG00000107929
Varsome BrowserLARP4B
ACMGLARP4B variants
VarityQ92615
Genomic Variants (DGV)LARP4B [DGVbeta]
DECIPHERLARP4B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLARP4B 
Mutations
ICGC Data PortalLARP4B 
TCGA Data PortalLARP4B 
Broad Tumor PortalLARP4B
OASIS PortalLARP4B [ Somatic mutations - Copy number]
Cancer Gene: CensusLARP4B 
Somatic Mutations in Cancer : COSMICLARP4B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLARP4B
Mutations and Diseases : HGMDLARP4B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLARP4B
DgiDB (Drug Gene Interaction Database)LARP4B
DoCM (Curated mutations)LARP4B
CIViC (Clinical Interpretations of Variants in Cancer)LARP4B
Cancer3DLARP4B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616513   
Orphanet
DisGeNETLARP4B
MedgenLARP4B
Genetic Testing Registry LARP4B
NextProtQ92615 [Medical]
GENETestsLARP4B
Target ValidationLARP4B
Huge Navigator LARP4B [HugePedia]
ClinGenLARP4B
Clinical trials, drugs, therapy
MyCancerGenomeLARP4B
Protein Interactions : CTDLARP4B
Pharm GKB GenePA165548762
PharosQ92615
Clinical trialLARP4B
Miscellaneous
canSAR (ICR)LARP4B
HarmonizomeLARP4B
DataMed IndexLARP4B
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLARP4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:15:36 CEST 2021

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