LARP4B (La ribonucleoprotein 4B)

2017-04-01  

Identity

HGNC
LOCATION
10p15.3
LOCUSID
ALIAS
KIAA0217,LARP5
FUSION GENES

Other Information

Locus ID:

NCBI: 23185
MIM: 616513
HGNC: 28987
Ensembl: ENSG00000107929

Variants:

dbSNP: 23185
ClinVar: 23185
TCGA: ENSG00000107929
COSMIC: LARP4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107929ENST00000316157Q92615
ENSG00000107929ENST00000406525B5MCU2
ENSG00000107929ENST00000412411X6RCG6
ENSG00000107929ENST00000440895H0Y641
ENSG00000107929ENST00000448368H0Y4V9
ENSG00000107929ENST00000476529V9GYI5
ENSG00000107929ENST00000614908A0A087X183

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
269330872016Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma.16
260017952015LARP4B is an AU-rich sequence associated factor that promotes mRNA accumulation and translation.9
317726832019Expression of La Ribonucleoprotein Domain Family Member 4B (LARP4B) in Liver Cancer and Their Clinical and Prognostic Significance.6
255342022015La-related protein 4B maintains murine MLL-AF9 leukemia stem cell self-renewal by regulating cell cycle progression.5
311732372019MicroRNA‑106b functions as an oncogene and regulates tumor viability and metastasis by targeting LARP4B in prostate cancer.1

Citation

Dessen P

LARP4B (La ribonucleoprotein 4B)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56893/larp4b