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LAS1L (LAS1 like, ribosome biogenesis factor)

Identity

Alias_namesLAS1-like (S. cerevisiae)
Alias_symbol (synonym)FLJ12525
Other aliasLas1-like
WTS
dJ475B7.2
HGNC (Hugo) LAS1L
LocusID (NCBI) 81887
Atlas_Id 56577
Location Xq12  [Link to chromosome band Xq12]
Location_base_pair Starts at 65512582 and ends at 65534806 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABCA1 (9q31.1) / LAS1L (Xq12)LAS1L (Xq12) / SDC3 (1p35.2)MSS51 (10q22.2) / LAS1L (Xq12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAS1L   25726
Cards
Entrez_Gene (NCBI)LAS1L  81887  LAS1 like, ribosome biogenesis factor
AliasesLas1-like; WTS; dJ475B7.2
GeneCards (Weizmann)LAS1L
Ensembl hg19 (Hinxton)ENSG00000001497 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000001497 [Gene_View]  chrX:65512582-65534806 [Contig_View]  LAS1L [Vega]
ICGC DataPortalENSG00000001497
TCGA cBioPortalLAS1L
AceView (NCBI)LAS1L
Genatlas (Paris)LAS1L
WikiGenes81887
SOURCE (Princeton)LAS1L
Genetics Home Reference (NIH)LAS1L
Genomic and cartography
GoldenPath hg38 (UCSC)LAS1L  -     chrX:65512582-65534806 -  Xq12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LAS1L  -     Xq12   [Description]    (hg19-Feb_2009)
EnsemblLAS1L - Xq12 [CytoView hg19]  LAS1L - Xq12 [CytoView hg38]
Mapping of homologs : NCBILAS1L [Mapview hg19]  LAS1L [Mapview hg38]
OMIM300964   309585   
Gene and transcription
Genbank (Entrez)AF116730 AK022587 AK054695 AK054817 AK074087
RefSeq transcript (Entrez)NM_001170649 NM_001170650 NM_031206
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LAS1L
Cluster EST : UnigeneHs.522675 [ NCBI ]
CGAP (NCI)Hs.522675
Alternative Splicing GalleryENSG00000001497
Gene ExpressionLAS1L [ NCBI-GEO ]   LAS1L [ EBI - ARRAY_EXPRESS ]   LAS1L [ SEEK ]   LAS1L [ MEM ]
Gene Expression Viewer (FireBrowse)LAS1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81887
GTEX Portal (Tissue expression)LAS1L
Human Protein AtlasENSG00000001497-LAS1L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4W2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4W2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4W2
Splice isoforms : SwissVarQ9Y4W2
PhosPhoSitePlusQ9Y4W2
Domains : Interpro (EBI)Las1   
Domain families : Pfam (Sanger)Las1 (PF04031)   
Domain families : Pfam (NCBI)pfam04031   
Conserved Domain (NCBI)LAS1L
DMDM Disease mutations81887
Blocks (Seattle)LAS1L
SuperfamilyQ9Y4W2
Human Protein Atlas [tissue]ENSG00000001497-LAS1L [tissue]
Peptide AtlasQ9Y4W2
HPRD06519
IPIIPI00641990   IPI00645869   IPI00009917   IPI00152781   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4W2
IntAct (EBI)Q9Y4W2
FunCoupENSG00000001497
BioGRIDLAS1L
STRING (EMBL)LAS1L
ZODIACLAS1L
Ontologies - Pathways
QuickGOQ9Y4W2
Ontology : AmiGORNA binding  nucleoplasm  nucleolus  cytoplasm  rRNA processing  membrane  MLL1 complex  
Ontology : EGO-EBIRNA binding  nucleoplasm  nucleolus  cytoplasm  rRNA processing  membrane  MLL1 complex  
NDEx NetworkLAS1L
Atlas of Cancer Signalling NetworkLAS1L
Wikipedia pathwaysLAS1L
Orthology - Evolution
OrthoDB81887
GeneTree (enSembl)ENSG00000001497
Phylogenetic Trees/Animal Genes : TreeFamLAS1L
HOVERGENQ9Y4W2
HOGENOMQ9Y4W2
Homologs : HomoloGeneLAS1L
Homology/Alignments : Family Browser (UCSC)LAS1L
Gene fusions - Rearrangements
Fusion: Tumor Portal LAS1L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAS1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAS1L
dbVarLAS1L
ClinVarLAS1L
1000_GenomesLAS1L 
Exome Variant ServerLAS1L
ExAC (Exome Aggregation Consortium)ENSG00000001497
GNOMAD BrowserENSG00000001497
Genetic variants : HAPMAP81887
Genomic Variants (DGV)LAS1L [DGVbeta]
DECIPHERLAS1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLAS1L 
Mutations
ICGC Data PortalLAS1L 
TCGA Data PortalLAS1L 
Broad Tumor PortalLAS1L
OASIS PortalLAS1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAS1L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLAS1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch LAS1L
DgiDB (Drug Gene Interaction Database)LAS1L
DoCM (Curated mutations)LAS1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAS1L (select a term)
intoGenLAS1L
Cancer3DLAS1L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300964    309585   
Orphanet3041    22935   
MedgenLAS1L
Genetic Testing Registry LAS1L
NextProtQ9Y4W2 [Medical]
TSGene81887
GENETestsLAS1L
Target ValidationLAS1L
Huge Navigator LAS1L [HugePedia]
snp3D : Map Gene to Disease81887
BioCentury BCIQLAS1L
ClinGenLAS1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81887
Chemical/Pharm GKB GenePA128394732
Clinical trialLAS1L
Miscellaneous
canSAR (ICR)LAS1L (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAS1L
EVEXLAS1L
GoPubMedLAS1L
iHOPLAS1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Nov 9 12:56:05 CET 2017

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