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LAT (linker for activation of T cells)

Identity

Other namesLAT1
pp36
HGNC (Hugo) LAT
LocusID (NCBI) 27040
Location 16p11.2
Location_base_pair Starts at 28996387 and ends at 29002104 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)LAT   18874
Entrez_Gene (NCBI)LAT  27040  linker for activation of T cells
Cards
GeneCards (Weizmann)LAT
Ensembl (Hinxton)ENSG00000213658 [Gene_View]  chr16:28996387-29002104 [Contig_View]  LAT [Vega]
AceView (NCBI)LAT
Genatlas (Paris)LAT
SOURCE (Stanford)NM_001014987 NM_001014988 NM_001014989 NM_014387
Genomic and cartography
GoldenPath (UCSC)LAT  -  16p11.2   chr16:28996387-29002104 +  16p11.2   [Description]    (hg19-Feb_2009)
EnsemblLAT - 16p11.2 [CytoView]
Mapping of homologs : NCBILAT [Mapview]
OMIM602354   
Gene and transcription
Genbank (Entrez)AF036905 AF036906 AJ223280 AK093815 AK307342
RefSeq transcript (SRS)NM_001014987 NM_001014988 NM_001014989 NM_014387
RefSeq transcript (Entrez)NM_001014987 NM_001014988 NM_001014989 NM_014387
RefSeq genomic (SRS)AC_000148 NC_000016 NC_018927 NT_010393 NW_001838231 NW_004078085
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NT_010393 NW_001838231 NW_004078085
Consensus coding sequences : CCDS (NCBI)LAT
Cluster EST : UnigeneHs.632179 [ SRS ] Hs.632179 [ NCBI ]
CGAP (NCI)Hs.632179
Alternative Splicing : Fast-db (Paris)GSHG0011081
Alternative Splicing GalleryENSG00000213658
Gene ExpressionLAT [ NCBI-GEO ]   LAT [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43561 (SRS) O43561 (Uniprot)
NextProtO43561
With graphics : InterProO43561
Splice isoforms : SwissVarO43561(Swissvar)
Domains : Interpro (SRS)Linker_for_activat_Tcells_prot   
Domains : Interpro (EBI)Linker_for_activat_Tcells_prot   
Related proteins : CluSTrO43561
Domain families : Pfam (SRS)
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM27040
Blocks (Seattle)O43561
Human Protein AtlasENSG00000213658
HPRD03832
IPIIPI00012888   IPI00218716   IPI01015021   IPI00930169   IPI00556022   
Protein Interaction databases
DIP (DOE-UCLA)O43561
IntAct (EBI)O43561
FunCoupENSG00000213658
REACTOMELAT
Protein Interaction Database27040
BioGRIDLAT
InParanoidO43561
Interologous Interaction database O43561
IntegromeDBLAT
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LAT
SNP (GeneSNP Utah)LAT
SNP : HGBaseLAT
Genetic variants : HAPMAPLAT
Somatic Mutations in Cancer : COSMICLAT 
CONAN: Copy Number AnalysisLAT 
Mutations and Diseases : HGMDLAT
OMIM602354   
GENETests602354   
Disease Genetic AssociationLAT
Huge Navigator LAT [HugePedia]  LAT [HugeCancerGEM]
Genomic VariantsLAT  LAT [DGVbeta]
snp3D : Map Gene to Disease27040
General knowledge
Homologs : HomoloGeneLAT
Homology/Alignments : Family Browser (UCSC)LAT
Phylogenetic Trees/Animal Genes : TreeFamLAT
Chemical/Protein Interactions : CTD27040
Chemical/Pharm GKB GenePA38728
Clinical trialLAT
Cancer Resource (Charite)ENSG00000213658
Ontology : AmiGOimmunological synapse  SH3/SH2 adaptor activity  protein binding  plasma membrane  immune response  integrin-mediated signaling pathway  Ras protein signal transduction  blood coagulation  signalosome  integral to membrane  calcium-mediated signaling  protein kinase binding  platelet activation  intracellular signal transduction  T cell activation  mast cell degranulation  membrane raft  T cell receptor signaling pathway  regulation of T cell activation  
Ontology : EGO-EBIimmunological synapse  SH3/SH2 adaptor activity  protein binding  plasma membrane  immune response  integrin-mediated signaling pathway  Ras protein signal transduction  blood coagulation  signalosome  integral to membrane  calcium-mediated signaling  protein kinase binding  platelet activation  intracellular signal transduction  T cell activation  mast cell degranulation  membrane raft  T cell receptor signaling pathway  regulation of T cell activation  
Pathways : BIOCARTARas-Independent pathway in NK cell-mediated cytotoxicity [Genes]    T Cell Receptor Signaling Pathway [Genes]   
Pathways : KEGGNatural killer cell mediated cytotoxicityFc epsilon RI signaling pathwayT cell receptor signaling pathway
Other databases
Probes
Litterature
PubMed96 Pubmed reference(s) in Entrez
PubGeneLAT
iHOPLAT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:41:51 CEST 2013
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