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LAX1 (lymphocyte transmembrane adaptor 1)

Identity

Alias_symbol (synonym)LAX
FLJ20340
Other alias
HGNC (Hugo) LAX1
LocusID (NCBI) 54900
Atlas_Id 65180
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 203734284 and ends at 203745480 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LAX1   26005
Cards
Entrez_Gene (NCBI)LAX1  54900  lymphocyte transmembrane adaptor 1
AliasesLAX
GeneCards (Weizmann)LAX1
Ensembl hg19 (Hinxton)ENSG00000122188 [Gene_View]  chr1:203734284-203745480 [Contig_View]  LAX1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000122188 [Gene_View]  chr1:203734284-203745480 [Contig_View]  LAX1 [Vega]
ICGC DataPortalENSG00000122188
TCGA cBioPortalLAX1
AceView (NCBI)LAX1
Genatlas (Paris)LAX1
WikiGenes54900
SOURCE (Princeton)LAX1
Genetics Home Reference (NIH)LAX1
Genomic and cartography
GoldenPath hg19 (UCSC)LAX1  -     chr1:203734284-203745480 +  1q32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LAX1  -     1q32.1   [Description]    (hg38-Dec_2013)
EnsemblLAX1 - 1q32.1 [CytoView hg19]  LAX1 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBILAX1 [Mapview hg19]  LAX1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK000347 AK225331 AK301076 AK301421 AY090784
RefSeq transcript (Entrez)NM_001136190 NM_001282878 NM_017773
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)LAX1
Cluster EST : UnigeneHs.272794 [ NCBI ]
CGAP (NCI)Hs.272794
Alternative Splicing GalleryENSG00000122188
Gene ExpressionLAX1 [ NCBI-GEO ]   LAX1 [ EBI - ARRAY_EXPRESS ]   LAX1 [ SEEK ]   LAX1 [ MEM ]
Gene Expression Viewer (FireBrowse)LAX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54900
GTEX Portal (Tissue expression)LAX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWV1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWV1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWV1
Splice isoforms : SwissVarQ8IWV1
PhosPhoSitePlusQ8IWV1
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)LAX1
DMDM Disease mutations54900
Blocks (Seattle)LAX1
SuperfamilyQ8IWV1
Human Protein AtlasENSG00000122188
Peptide AtlasQ8IWV1
HPRD08312
IPIIPI00301971   IPI00642381   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWV1
IntAct (EBI)Q8IWV1
FunCoupENSG00000122188
BioGRIDLAX1
STRING (EMBL)LAX1
ZODIACLAX1
Ontologies - Pathways
QuickGOQ8IWV1
Ontology : AmiGOinactivation of MAPK activity  protein binding  cytoplasm  Golgi apparatus  plasma membrane  immune response  membrane  integral component of membrane  protein kinase binding  intracellular signal transduction  B cell activation  SH2 domain binding  membrane raft  immunoglobulin secretion  antigen receptor-mediated signaling pathway  negative regulation of T cell activation  
Ontology : EGO-EBIinactivation of MAPK activity  protein binding  cytoplasm  Golgi apparatus  plasma membrane  immune response  membrane  integral component of membrane  protein kinase binding  intracellular signal transduction  B cell activation  SH2 domain binding  membrane raft  immunoglobulin secretion  antigen receptor-mediated signaling pathway  negative regulation of T cell activation  
NDEx NetworkLAX1
Atlas of Cancer Signalling NetworkLAX1
Wikipedia pathwaysLAX1
Orthology - Evolution
OrthoDB54900
GeneTree (enSembl)ENSG00000122188
Phylogenetic Trees/Animal Genes : TreeFamLAX1
HOVERGENQ8IWV1
HOGENOMQ8IWV1
Homologs : HomoloGeneLAX1
Homology/Alignments : Family Browser (UCSC)LAX1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLAX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LAX1
dbVarLAX1
ClinVarLAX1
1000_GenomesLAX1 
Exome Variant ServerLAX1
ExAC (Exome Aggregation Consortium)LAX1 (select the gene name)
Genetic variants : HAPMAP54900
Genomic Variants (DGV)LAX1 [DGVbeta]
DECIPHER (Syndromes)1:203734284-203745480  ENSG00000122188
CONAN: Copy Number AnalysisLAX1 
Mutations
ICGC Data PortalLAX1 
TCGA Data PortalLAX1 
Broad Tumor PortalLAX1
OASIS PortalLAX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLAX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLAX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LAX1
DgiDB (Drug Gene Interaction Database)LAX1
DoCM (Curated mutations)LAX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LAX1 (select a term)
intoGenLAX1
Cancer3DLAX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenLAX1
Genetic Testing Registry LAX1
NextProtQ8IWV1 [Medical]
TSGene54900
GENETestsLAX1
Huge Navigator LAX1 [HugePedia]
snp3D : Map Gene to Disease54900
BioCentury BCIQLAX1
ClinGenLAX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54900
Chemical/Pharm GKB GenePA142671569
Clinical trialLAX1
Miscellaneous
canSAR (ICR)LAX1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLAX1
EVEXLAX1
GoPubMedLAX1
iHOPLAX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:10:47 CET 2017

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