| Nomenclature |
|---|
| HGNC (Hugo) | LBX1 16960 |
| Cards |
|---|
| Entrez_Gene (NCBI) | LBX1 10660 ladybird homeobox 1 |
| Aliases | HPX-6; HPX6; LBX1H; homeobox |
| GeneCards (Weizmann) | LBX1 |
| Ensembl hg19 (Hinxton) | ENSG00000138136 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000138136 [Gene_View] ENSG00000138136 [Sequence] chr10:101226976-101228960 [Contig_View] LBX1 [Vega] |
| ICGC DataPortal | ENSG00000138136 |
| TCGA cBioPortal | LBX1 |
| AceView (NCBI) | LBX1 |
| Genatlas (Paris) | LBX1 |
| WikiGenes | 10660 |
| SOURCE (Princeton) | LBX1 |
| Genetics Home Reference (NIH) | LBX1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | LBX1 - chr10:101226976-101228960 - 10q24.32 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | LBX1 - 10q24.32 [Description] (hg19-Feb_2009) |
| GoldenPath | LBX1 - 10q24.32 [CytoView hg19] LBX1 - 10q24.32 [CytoView hg38] |
| Genome Data Viewer NCBI | LBX1 [Mapview hg19] |
| OMIM | 604255 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AJ004949 BC069156 BC136321 X74863 X90828 |
| RefSeq transcript (Entrez) | NM_006562 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | LBX1 |
| Alternative Splicing Gallery | ENSG00000138136 |
| Gene Expression | LBX1 [ NCBI-GEO ] LBX1 [ EBI - ARRAY_EXPRESS ]
LBX1 [ SEEK ] LBX1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | LBX1 [ Firebrowse - Broad ] |
| Genevisible | Expression of LBX1 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 10660 |
| GTEX Portal (Tissue expression) | LBX1 |
| Human Protein Atlas | ENSG00000138136-LBX1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P52954 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P52954 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P52954 |
| Splice isoforms : SwissVar | P52954 |
| PhosPhoSitePlus | P52954 |
| Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
| Domains : Interpro (EBI) | Homeobox-like_sf Homeobox_CS Homeobox_dom HTH_motif |
| Domain families : Pfam (Sanger) | Homeodomain (PF00046) |
| Domain families : Pfam (NCBI) | pfam00046 |
| Domain families : Smart (EMBL) | HOX (SM00389) |
| Conserved Domain (NCBI) | LBX1 |
| DMDM Disease mutations | 10660 |
| Superfamily | P52954 |
| Human Protein Atlas [tissue] | ENSG00000138136-LBX1 [tissue] |
| Peptide Atlas | P52954 |
| HPRD | 09178 |
| IPI | IPI00006058 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P52954 |
| IntAct (EBI) | P52954 |
| FunCoup | ENSG00000138136 |
| BioGRID | LBX1 |
| STRING (EMBL) | LBX1 |
| ZODIAC | LBX1 |
| Ontologies - Pathways |
|---|
| QuickGO | P52954 |
| Ontology : AmiGO | nuclear chromatin DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific heart looping nucleus transcription factor complex muscle organ development negative regulation of cell proliferation anatomical structure morphogenesis spinal cord motor neuron differentiation regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification sequence-specific DNA binding negative regulation of neuron differentiation neuron fate determination |
| Ontology : EGO-EBI | nuclear chromatin DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific heart looping nucleus transcription factor complex muscle organ development negative regulation of cell proliferation anatomical structure morphogenesis spinal cord motor neuron differentiation regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification sequence-specific DNA binding negative regulation of neuron differentiation neuron fate determination |
| NDEx Network | LBX1 |
| Atlas of Cancer Signalling Network | LBX1 |
| Wikipedia pathways | LBX1 |
| Orthology - Evolution |
|---|
| OrthoDB | 10660 |
| GeneTree (enSembl) | ENSG00000138136 |
| Phylogenetic Trees/Animal Genes : TreeFam | LBX1 |
| HOGENOM | P52954 |
| Homologs : HomoloGene | LBX1 |
| Homology/Alignments : Family Browser (UCSC) | LBX1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | LBX1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | LBX1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | LBX1 |
| dbVar | LBX1 |
| ClinVar | LBX1 |
| 1000_Genomes | LBX1 |
| Exome Variant Server | LBX1 |
| GNOMAD Browser | ENSG00000138136 |
| Varsome Browser | LBX1 |
| Genetic variants : HAPMAP | 10660 |
| Genomic Variants (DGV) | LBX1 [DGVbeta] |
| DECIPHER | LBX1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | LBX1 |
| Mutations |
|---|
| ICGC Data Portal | LBX1 |
| TCGA Data Portal | LBX1 |
| Broad Tumor Portal | LBX1 |
| OASIS Portal | LBX1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | LBX1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | LBX1 |
| Mutations and Diseases : HGMD | LBX1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | select LBX1 |
| DgiDB (Drug Gene Interaction Database) | LBX1 |
| DoCM (Curated mutations) | LBX1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | LBX1 (select a term) |
| intoGen | LBX1 |
| Cancer3D | LBX1 (select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 604255 |
| Orphanet | |
| DisGeNET | LBX1 |
| Medgen | LBX1 |
| Genetic Testing Registry | LBX1
|
| NextProt | P52954 [Medical] |
| TSGene | 10660 |
| GENETests | LBX1 |
| Open Targets Genetics | ENSG00000138136 [validation] |
| snp3D : Map Gene to Disease | 10660 |
| BioCentury BCIQ | LBX1 |
| ClinGen | LBX1 (curated) |
| Clinical trials, drugs, therapy |
|---|
| Protein Interactions : CTD | 10660 |
| Pharm GKB Gene | PA142671561 |
| Clinical trial | LBX1 |
| Miscellaneous |
|---|
| canSAR (ICR) | LBX1 (select the gene name) |
| Harmonizome | LBX1 |
| DataMed Index | LBX1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 28 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | LBX1 |
| EVEX | LBX1 |
