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LCE2B (late cornified envelope 2B)

Identity

Alias_namesSPRL1B
small proline rich-like (epidermal differentiation complex) 1B
Alias_symbol (synonym)LEP10
XP5
Other alias
HGNC (Hugo) LCE2B
LocusID (NCBI) 26239
Atlas_Id 65195
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 152686123 and ends at 152687400 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LCE2B   16610
Cards
Entrez_Gene (NCBI)LCE2B  26239  late cornified envelope 2B
AliasesLEP10; SPRL1B; XP5
GeneCards (Weizmann)LCE2B
Ensembl hg19 (Hinxton)ENSG00000159455 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159455 [Gene_View]  chr1:152686123-152687400 [Contig_View]  LCE2B [Vega]
ICGC DataPortalENSG00000159455
TCGA cBioPortalLCE2B
AceView (NCBI)LCE2B
Genatlas (Paris)LCE2B
WikiGenes26239
SOURCE (Princeton)LCE2B
Genetics Home Reference (NIH)LCE2B
Genomic and cartography
GoldenPath hg38 (UCSC)LCE2B  -     chr1:152686123-152687400 +  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LCE2B  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblLCE2B - 1q21.3 [CytoView hg19]  LCE2B - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBILCE2B [Mapview hg19]  LCE2B [Mapview hg38]
OMIM612610   
Gene and transcription
Genbank (Entrez)AF005080 AF086289 BC117235 BC117237 BC146413
RefSeq transcript (Entrez)NM_014357
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LCE2B
Cluster EST : UnigeneHs.234766 [ NCBI ]
CGAP (NCI)Hs.234766
Alternative Splicing GalleryENSG00000159455
Gene ExpressionLCE2B [ NCBI-GEO ]   LCE2B [ EBI - ARRAY_EXPRESS ]   LCE2B [ SEEK ]   LCE2B [ MEM ]
Gene Expression Viewer (FireBrowse)LCE2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26239
GTEX Portal (Tissue expression)LCE2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14633   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14633  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14633
Splice isoforms : SwissVarO14633
PhosPhoSitePlusO14633
Domains : Interpro (EBI)LCE    SPRR/LCE   
Domain families : Pfam (Sanger)LCE (PF14672)   
Domain families : Pfam (NCBI)pfam14672   
Conserved Domain (NCBI)LCE2B
DMDM Disease mutations26239
Blocks (Seattle)LCE2B
SuperfamilyO14633
Human Protein AtlasENSG00000159455
Peptide AtlasO14633
HPRD17260
IPIIPI00003867   
Protein Interaction databases
DIP (DOE-UCLA)O14633
IntAct (EBI)O14633
FunCoupENSG00000159455
BioGRIDLCE2B
STRING (EMBL)LCE2B
ZODIACLCE2B
Ontologies - Pathways
QuickGOO14633
Ontology : AmiGOcornified envelope  molecular_function  structural molecule activity  cellular_component  cytoplasm  epidermis development  peptide cross-linking  keratinocyte differentiation  keratinization  
Ontology : EGO-EBIcornified envelope  molecular_function  structural molecule activity  cellular_component  cytoplasm  epidermis development  peptide cross-linking  keratinocyte differentiation  keratinization  
NDEx NetworkLCE2B
Atlas of Cancer Signalling NetworkLCE2B
Wikipedia pathwaysLCE2B
Orthology - Evolution
OrthoDB26239
GeneTree (enSembl)ENSG00000159455
Phylogenetic Trees/Animal Genes : TreeFamLCE2B
HOVERGENO14633
HOGENOMO14633
Homologs : HomoloGeneLCE2B
Homology/Alignments : Family Browser (UCSC)LCE2B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLCE2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LCE2B
dbVarLCE2B
ClinVarLCE2B
1000_GenomesLCE2B 
Exome Variant ServerLCE2B
ExAC (Exome Aggregation Consortium)LCE2B (select the gene name)
Genetic variants : HAPMAP26239
Genomic Variants (DGV)LCE2B [DGVbeta]
DECIPHERLCE2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLCE2B 
Mutations
ICGC Data PortalLCE2B 
TCGA Data PortalLCE2B 
Broad Tumor PortalLCE2B
OASIS PortalLCE2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLCE2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLCE2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LCE2B
DgiDB (Drug Gene Interaction Database)LCE2B
DoCM (Curated mutations)LCE2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LCE2B (select a term)
intoGenLCE2B
Cancer3DLCE2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612610   
Orphanet
MedgenLCE2B
Genetic Testing Registry LCE2B
NextProtO14633 [Medical]
TSGene26239
GENETestsLCE2B
Target ValidationLCE2B
Huge Navigator LCE2B [HugePedia]
snp3D : Map Gene to Disease26239
BioCentury BCIQLCE2B
ClinGenLCE2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26239
Chemical/Pharm GKB GenePA38170
Clinical trialLCE2B
Miscellaneous
canSAR (ICR)LCE2B (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLCE2B
EVEXLCE2B
GoPubMedLCE2B
iHOPLCE2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:12:33 CEST 2017

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