LCE3A (late cornified envelope 3A)

2014-11-01 Affiliation

Identity

HGNC

LCE3A

LOCATION

1q21.3

LOCUSID

353142

ALIAS

LEP13

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 353142
MIM: 612613
HGNC: 29461
Ensembl: ENSG00000185962

Variants:

dbSNP: 353142
ClinVar: 353142
TCGA: ENSG00000185962
COSMIC: LCE3A

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000185962	ENST00000335674	Q5TA76

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Developmental Biology	REACTOME	R-HSA-1266738
Keratinization	REACTOME	R-HSA-6805567
Formation of the cornified envelope	REACTOME	R-HSA-6809371

References

Pubmed ID	Year	Title	Citations
15854049	2005	Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation.	56
27048876	2016	Increased Risk of Psoriasis due to combined effect of HLA-Cw6 and LCE3 risk alleles in Indian population.	4
19601998	2009	Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.	3
29397434	2018	Association between LCE gene polymorphisms and psoriasis vulgaris among Mongolians from Inner Mongolia.	1

Citation

Dessen P

LCE3A (late cornified envelope 3A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/65198/lce3a