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LCE4A (late cornified envelope 4A)

Identity

Alias_namesSPRL4A
small proline rich-like (epidermal differentiation complex) 4A
Alias_symbol (synonym)LEP8
Other alias
HGNC (Hugo) LCE4A
LocusID (NCBI) 199834
Atlas_Id 65203
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 152709047 and ends at 152709434 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LCE4A   16613
Cards
Entrez_Gene (NCBI)LCE4A  199834  late cornified envelope 4A
AliasesLEP8; SPRL4A
GeneCards (Weizmann)LCE4A
Ensembl hg19 (Hinxton)ENSG00000187170 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187170 [Gene_View]  chr1:152709047-152709434 [Contig_View]  LCE4A [Vega]
ICGC DataPortalENSG00000187170
TCGA cBioPortalLCE4A
AceView (NCBI)LCE4A
Genatlas (Paris)LCE4A
WikiGenes199834
SOURCE (Princeton)LCE4A
Genetics Home Reference (NIH)LCE4A
Genomic and cartography
GoldenPath hg38 (UCSC)LCE4A  -     chr1:152709047-152709434 +  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LCE4A  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblLCE4A - 1q21.3 [CytoView hg19]  LCE4A - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBILCE4A [Mapview hg19]  LCE4A [Mapview hg38]
OMIM612618   
Gene and transcription
Genbank (Entrez)BC113446 BC113448 HQ258036
RefSeq transcript (Entrez)NM_178356
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LCE4A
Cluster EST : UnigeneHs.447955 [ NCBI ]
CGAP (NCI)Hs.447955
Alternative Splicing GalleryENSG00000187170
Gene ExpressionLCE4A [ NCBI-GEO ]   LCE4A [ EBI - ARRAY_EXPRESS ]   LCE4A [ SEEK ]   LCE4A [ MEM ]
Gene Expression Viewer (FireBrowse)LCE4A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)199834
GTEX Portal (Tissue expression)LCE4A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TA78   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TA78  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TA78
Splice isoforms : SwissVarQ5TA78
PhosPhoSitePlusQ5TA78
Domains : Interpro (EBI)LCE    SPRR/LCE   
Domain families : Pfam (Sanger)LCE (PF14672)   
Domain families : Pfam (NCBI)pfam14672   
Conserved Domain (NCBI)LCE4A
DMDM Disease mutations199834
Blocks (Seattle)LCE4A
SuperfamilyQ5TA78
Human Protein AtlasENSG00000187170
Peptide AtlasQ5TA78
HPRD17264
IPIIPI00374336   
Protein Interaction databases
DIP (DOE-UCLA)Q5TA78
IntAct (EBI)Q5TA78
FunCoupENSG00000187170
BioGRIDLCE4A
STRING (EMBL)LCE4A
ZODIACLCE4A
Ontologies - Pathways
QuickGOQ5TA78
Ontology : AmiGOcornified envelope  structural molecule activity  protein binding  cytoplasm  peptide cross-linking  keratinocyte differentiation  keratinization  
Ontology : EGO-EBIcornified envelope  structural molecule activity  protein binding  cytoplasm  peptide cross-linking  keratinocyte differentiation  keratinization  
NDEx NetworkLCE4A
Atlas of Cancer Signalling NetworkLCE4A
Wikipedia pathwaysLCE4A
Orthology - Evolution
OrthoDB199834
GeneTree (enSembl)ENSG00000187170
Phylogenetic Trees/Animal Genes : TreeFamLCE4A
HOVERGENQ5TA78
HOGENOMQ5TA78
Homologs : HomoloGeneLCE4A
Homology/Alignments : Family Browser (UCSC)LCE4A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLCE4A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LCE4A
dbVarLCE4A
ClinVarLCE4A
1000_GenomesLCE4A 
Exome Variant ServerLCE4A
ExAC (Exome Aggregation Consortium)LCE4A (select the gene name)
Genetic variants : HAPMAP199834
Genomic Variants (DGV)LCE4A [DGVbeta]
DECIPHERLCE4A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLCE4A 
Mutations
ICGC Data PortalLCE4A 
TCGA Data PortalLCE4A 
Broad Tumor PortalLCE4A
OASIS PortalLCE4A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLCE4A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLCE4A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LCE4A
DgiDB (Drug Gene Interaction Database)LCE4A
DoCM (Curated mutations)LCE4A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LCE4A (select a term)
intoGenLCE4A
Cancer3DLCE4A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612618   
Orphanet
MedgenLCE4A
Genetic Testing Registry LCE4A
NextProtQ5TA78 [Medical]
TSGene199834
GENETestsLCE4A
Target ValidationLCE4A
Huge Navigator LCE4A [HugePedia]
snp3D : Map Gene to Disease199834
BioCentury BCIQLCE4A
ClinGenLCE4A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD199834
Chemical/Pharm GKB GenePA38172
Clinical trialLCE4A
Miscellaneous
canSAR (ICR)LCE4A (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLCE4A
EVEXLCE4A
GoPubMedLCE4A
iHOPLCE4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:12:35 CEST 2017

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