Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LCE5A (late cornified envelope 5A)

Identity

Alias_namesSPRL5A
small proline rich-like (epidermal differentiation complex) 5A
Alias_symbol (synonym)LEP18
Other alias
HGNC (Hugo) LCE5A
LocusID (NCBI) 254910
Atlas_Id 65204
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 152510844 and ends at 152512177 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LCE5A   16614
Cards
Entrez_Gene (NCBI)LCE5A  254910  late cornified envelope 5A
AliasesLEP18; SPRL5A
GeneCards (Weizmann)LCE5A
Ensembl hg19 (Hinxton)ENSG00000186207 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186207 [Gene_View]  chr1:152510844-152512177 [Contig_View]  LCE5A [Vega]
ICGC DataPortalENSG00000186207
TCGA cBioPortalLCE5A
AceView (NCBI)LCE5A
Genatlas (Paris)LCE5A
WikiGenes254910
SOURCE (Princeton)LCE5A
Genetics Home Reference (NIH)LCE5A
Genomic and cartography
GoldenPath hg38 (UCSC)LCE5A  -     chr1:152510844-152512177 +  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LCE5A  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblLCE5A - 1q21.3 [CytoView hg19]  LCE5A - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBILCE5A [Mapview hg19]  LCE5A [Mapview hg38]
OMIM612619   
Gene and transcription
Genbank (Entrez)AW291010 BC140434 BC156866
RefSeq transcript (Entrez)NM_178438
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LCE5A
Cluster EST : UnigeneHs.516410 [ NCBI ]
CGAP (NCI)Hs.516410
Alternative Splicing GalleryENSG00000186207
Gene ExpressionLCE5A [ NCBI-GEO ]   LCE5A [ EBI - ARRAY_EXPRESS ]   LCE5A [ SEEK ]   LCE5A [ MEM ]
Gene Expression Viewer (FireBrowse)LCE5A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)254910
GTEX Portal (Tissue expression)LCE5A
Human Protein AtlasENSG00000186207-LCE5A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TCM9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TCM9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TCM9
Splice isoforms : SwissVarQ5TCM9
PhosPhoSitePlusQ5TCM9
Domains : Interpro (EBI)LCE    SPRR/LCE   
Domain families : Pfam (Sanger)LCE (PF14672)   
Domain families : Pfam (NCBI)pfam14672   
Conserved Domain (NCBI)LCE5A
DMDM Disease mutations254910
Blocks (Seattle)LCE5A
SuperfamilyQ5TCM9
Human Protein Atlas [tissue]ENSG00000186207-LCE5A [tissue]
Peptide AtlasQ5TCM9
HPRD17265
IPIIPI00374868   
Protein Interaction databases
DIP (DOE-UCLA)Q5TCM9
IntAct (EBI)Q5TCM9
FunCoupENSG00000186207
BioGRIDLCE5A
STRING (EMBL)LCE5A
ZODIACLCE5A
Ontologies - Pathways
QuickGOQ5TCM9
Ontology : AmiGOcornified envelope  structural molecule activity  cytoplasm  peptide cross-linking  keratinocyte differentiation  keratinization  
Ontology : EGO-EBIcornified envelope  structural molecule activity  cytoplasm  peptide cross-linking  keratinocyte differentiation  keratinization  
NDEx NetworkLCE5A
Atlas of Cancer Signalling NetworkLCE5A
Wikipedia pathwaysLCE5A
Orthology - Evolution
OrthoDB254910
GeneTree (enSembl)ENSG00000186207
Phylogenetic Trees/Animal Genes : TreeFamLCE5A
HOVERGENQ5TCM9
HOGENOMQ5TCM9
Homologs : HomoloGeneLCE5A
Homology/Alignments : Family Browser (UCSC)LCE5A
Gene fusions - Rearrangements
Tumor Fusion PortalLCE5A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLCE5A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LCE5A
dbVarLCE5A
ClinVarLCE5A
1000_GenomesLCE5A 
Exome Variant ServerLCE5A
ExAC (Exome Aggregation Consortium)ENSG00000186207
GNOMAD BrowserENSG00000186207
Genetic variants : HAPMAP254910
Genomic Variants (DGV)LCE5A [DGVbeta]
DECIPHERLCE5A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLCE5A 
Mutations
ICGC Data PortalLCE5A 
TCGA Data PortalLCE5A 
Broad Tumor PortalLCE5A
OASIS PortalLCE5A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLCE5A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLCE5A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LCE5A
DgiDB (Drug Gene Interaction Database)LCE5A
DoCM (Curated mutations)LCE5A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LCE5A (select a term)
intoGenLCE5A
Cancer3DLCE5A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612619   
Orphanet
DisGeNETLCE5A
MedgenLCE5A
Genetic Testing Registry LCE5A
NextProtQ5TCM9 [Medical]
TSGene254910
GENETestsLCE5A
Target ValidationLCE5A
Huge Navigator LCE5A [HugePedia]
snp3D : Map Gene to Disease254910
BioCentury BCIQLCE5A
ClinGenLCE5A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD254910
Chemical/Pharm GKB GenePA38173
Clinical trialLCE5A
Miscellaneous
canSAR (ICR)LCE5A (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLCE5A
EVEXLCE5A
GoPubMedLCE5A
iHOPLCE5A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Nov 20 19:36:04 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.