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LCMT2 (leucine carboxyl methyltransferase 2)

Identity

Alias_symbol (synonym)KIAA0547
MGC9534
TYW4
PPM2
Other alias
HGNC (Hugo) LCMT2
LocusID (NCBI) 9836
Atlas_Id 41132
Location 15q15.3  [Link to chromosome band 15q15]
Location_base_pair Starts at 43327776 and ends at 43330622 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LCMT2   17558
Cards
Entrez_Gene (NCBI)LCMT2  9836  leucine carboxyl methyltransferase 2
AliasesPPM2; TYW4
GeneCards (Weizmann)LCMT2
Ensembl hg19 (Hinxton)ENSG00000168806 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168806 [Gene_View]  chr15:43327776-43330622 [Contig_View]  LCMT2 [Vega]
ICGC DataPortalENSG00000168806
TCGA cBioPortalLCMT2
AceView (NCBI)LCMT2
Genatlas (Paris)LCMT2
WikiGenes9836
SOURCE (Princeton)LCMT2
Genetics Home Reference (NIH)LCMT2
Genomic and cartography
GoldenPath hg38 (UCSC)LCMT2  -     chr15:43327776-43330622 -  15q15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LCMT2  -     15q15.3   [Description]    (hg19-Feb_2009)
EnsemblLCMT2 - 15q15.3 [CytoView hg19]  LCMT2 - 15q15.3 [CytoView hg38]
Mapping of homologs : NCBILCMT2 [Mapview hg19]  LCMT2 [Mapview hg38]
OMIM611246   
Gene and transcription
Genbank (Entrez)AF265443 AK292587 AK300820 AW505587 BC015949
RefSeq transcript (Entrez)NM_014793
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LCMT2
Cluster EST : UnigeneHs.745356 [ NCBI ]
CGAP (NCI)Hs.745356
Alternative Splicing GalleryENSG00000168806
Gene ExpressionLCMT2 [ NCBI-GEO ]   LCMT2 [ EBI - ARRAY_EXPRESS ]   LCMT2 [ SEEK ]   LCMT2 [ MEM ]
Gene Expression Viewer (FireBrowse)LCMT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9836
GTEX Portal (Tissue expression)LCMT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60294   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60294  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60294
Splice isoforms : SwissVarO60294
Catalytic activity : Enzyme2.1.1.290 [ Enzyme-Expasy ]   2.1.1.2902.1.1.290 [ IntEnz-EBI ]   2.1.1.290 [ BRENDA ]   2.1.1.290 [ KEGG ]   
PhosPhoSitePlusO60294
Domains : Interpro (EBI)Kelch-typ_b-propeller    Ppm1/Ppm2/Tcmp    SAM-dependent_MTases   
Domain families : Pfam (Sanger)LCM (PF04072)   
Domain families : Pfam (NCBI)pfam04072   
Conserved Domain (NCBI)LCMT2
DMDM Disease mutations9836
Blocks (Seattle)LCMT2
SuperfamilyO60294
Human Protein AtlasENSG00000168806
Peptide AtlasO60294
HPRD17267
IPIIPI00171712   IPI01010876   
Protein Interaction databases
DIP (DOE-UCLA)O60294
IntAct (EBI)O60294
FunCoupENSG00000168806
BioGRIDLCMT2
STRING (EMBL)LCMT2
ZODIACLCMT2
Ontologies - Pathways
QuickGOO60294
Ontology : AmiGOprotein binding  cytoplasm  cytosol  tRNA modification  tRNA methyltransferase activity  tRNA methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  tRNA methylation  wybutosine biosynthetic process  
Ontology : EGO-EBIprotein binding  cytoplasm  cytosol  tRNA modification  tRNA methyltransferase activity  tRNA methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  tRNA methylation  wybutosine biosynthetic process  
NDEx NetworkLCMT2
Atlas of Cancer Signalling NetworkLCMT2
Wikipedia pathwaysLCMT2
Orthology - Evolution
OrthoDB9836
GeneTree (enSembl)ENSG00000168806
Phylogenetic Trees/Animal Genes : TreeFamLCMT2
HOVERGENO60294
HOGENOMO60294
Homologs : HomoloGeneLCMT2
Homology/Alignments : Family Browser (UCSC)LCMT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLCMT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LCMT2
dbVarLCMT2
ClinVarLCMT2
1000_GenomesLCMT2 
Exome Variant ServerLCMT2
ExAC (Exome Aggregation Consortium)LCMT2 (select the gene name)
Genetic variants : HAPMAP9836
Genomic Variants (DGV)LCMT2 [DGVbeta]
DECIPHERLCMT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLCMT2 
Mutations
ICGC Data PortalLCMT2 
TCGA Data PortalLCMT2 
Broad Tumor PortalLCMT2
OASIS PortalLCMT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLCMT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLCMT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LCMT2
DgiDB (Drug Gene Interaction Database)LCMT2
DoCM (Curated mutations)LCMT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LCMT2 (select a term)
intoGenLCMT2
Cancer3DLCMT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611246   
Orphanet
MedgenLCMT2
Genetic Testing Registry LCMT2
NextProtO60294 [Medical]
TSGene9836
GENETestsLCMT2
Target ValidationLCMT2
Huge Navigator LCMT2 [HugePedia]
snp3D : Map Gene to Disease9836
BioCentury BCIQLCMT2
ClinGenLCMT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9836
Chemical/Pharm GKB GenePA134878443
Clinical trialLCMT2
Miscellaneous
canSAR (ICR)LCMT2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLCMT2
EVEXLCMT2
GoPubMedLCMT2
iHOPLCMT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:05:07 CEST 2017

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