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LCOR (ligand dependent nuclear receptor corepressor)

Identity

Alias_symbol (synonym)MLR2
FLJ38026
KIAA1795
Other aliasC10orf12
HGNC (Hugo) LCOR
LocusID (NCBI) 84458
Atlas_Id 52507
Location 10q24.1  [Link to chromosome band 10q24]
Location_base_pair Starts at 96832260 and ends at 96964441 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LCOR (10q24.1) / C10orf131 (10q24.1)LCOR (10q24.1) / CPNE8 (12q12)LCOR (10q24.1) / FAM111A (11q12.1)
LCOR (10q24.1) / LCOR (10q24.1)LCOR (10q24.1) / PNLIPRP3 (10q25.3)MAN1A1 (6q22.31) / LCOR (10q24.1)
LCOR 10q24.1 / C10orf131 10q24.1LCOR 10q24.1 / CPNE8 12q12LCOR 10q24.1 / PNLIPRP3 10q25.3
MAN1A1 6q22.31 / LCOR 10q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LCOR   29503
Cards
Entrez_Gene (NCBI)LCOR  84458  ligand dependent nuclear receptor corepressor
AliasesC10orf12; MLR2
GeneCards (Weizmann)LCOR
Ensembl hg19 (Hinxton)ENSG00000196233 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196233 [Gene_View]  chr10:96832260-96964441 [Contig_View]  LCOR [Vega]
ICGC DataPortalENSG00000196233
TCGA cBioPortalLCOR
AceView (NCBI)LCOR
Genatlas (Paris)LCOR
WikiGenes84458
SOURCE (Princeton)LCOR
Genetics Home Reference (NIH)LCOR
Genomic and cartography
GoldenPath hg38 (UCSC)LCOR  -     chr10:96832260-96964441 +  10q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LCOR  -     10q24.1   [Description]    (hg19-Feb_2009)
EnsemblLCOR - 10q24.1 [CytoView hg19]  LCOR - 10q24.1 [CytoView hg38]
Mapping of homologs : NCBILCOR [Mapview hg19]  LCOR [Mapview hg38]
OMIM607698   
Gene and transcription
Genbank (Entrez)AB058698 AB072899 AI571097 AK023084 AK023248
RefSeq transcript (Entrez)NM_001170765 NM_001170766 NM_001346516 NM_015652 NM_032440
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LCOR
Cluster EST : UnigeneHs.745068 [ NCBI ]
CGAP (NCI)Hs.745068
Alternative Splicing GalleryENSG00000196233
Gene ExpressionLCOR [ NCBI-GEO ]   LCOR [ EBI - ARRAY_EXPRESS ]   LCOR [ SEEK ]   LCOR [ MEM ]
Gene Expression Viewer (FireBrowse)LCOR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84458
GTEX Portal (Tissue expression)LCOR
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JN0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JN0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JN0
Splice isoforms : SwissVarQ96JN0
PhosPhoSitePlusQ96JN0
Domaine pattern : Prosite (Expaxy)HTH_PSQ (PS50960)   
Domains : Interpro (EBI)Homeobox-like    HTH_Psq   
Domain families : Pfam (Sanger)HTH_psq (PF05225)   
Domain families : Pfam (NCBI)pfam05225   
Conserved Domain (NCBI)LCOR
DMDM Disease mutations84458
Blocks (Seattle)LCOR
PDB (SRS)2COB   
PDB (PDBSum)2COB   
PDB (IMB)2COB   
PDB (RSDB)2COB   
Structural Biology KnowledgeBase2COB   
SCOP (Structural Classification of Proteins)2COB   
CATH (Classification of proteins structures)2COB   
SuperfamilyQ96JN0
Human Protein AtlasENSG00000196233
Peptide AtlasQ96JN0
HPRD07609
IPIIPI00478371   IPI00759763   
Protein Interaction databases
DIP (DOE-UCLA)Q96JN0
IntAct (EBI)Q96JN0
FunCoupENSG00000196233
BioGRIDLCOR
STRING (EMBL)LCOR
ZODIACLCOR
Ontologies - Pathways
QuickGOQ96JN0
Ontology : AmiGODNA binding  protein binding  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  
Ontology : EGO-EBIDNA binding  protein binding  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  
NDEx NetworkLCOR
Atlas of Cancer Signalling NetworkLCOR
Wikipedia pathwaysLCOR
Orthology - Evolution
OrthoDB84458
GeneTree (enSembl)ENSG00000196233
Phylogenetic Trees/Animal Genes : TreeFamLCOR
HOVERGENQ96JN0
HOGENOMQ96JN0
Homologs : HomoloGeneLCOR
Homology/Alignments : Family Browser (UCSC)LCOR
Gene fusions - Rearrangements
Fusion : MitelmanLCOR/C10orf131 [10q24.1/10q24.1]  
Fusion : MitelmanLCOR/CPNE8 [10q24.1/12q12]  [t(10;12)(q24;q12)]  
Fusion : MitelmanLCOR/PNLIPRP3 [10q24.1/10q25.3]  [t(10;10)(q24;q25)]  
Fusion : MitelmanMAN1A1/LCOR [6q22.31/10q24.1]  [t(6;10)(q22;q24)]  
Fusion: TCGALCOR 10q24.1 C10orf131 10q24.1 PRAD
Fusion: TCGALCOR 10q24.1 CPNE8 12q12 BRCA
Fusion: TCGALCOR 10q24.1 PNLIPRP3 10q25.3 LUAD
Fusion: TCGAMAN1A1 6q22.31 LCOR 10q24.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLCOR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LCOR
dbVarLCOR
ClinVarLCOR
1000_GenomesLCOR 
Exome Variant ServerLCOR
ExAC (Exome Aggregation Consortium)LCOR (select the gene name)
Genetic variants : HAPMAP84458
Genomic Variants (DGV)LCOR [DGVbeta]
DECIPHERLCOR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLCOR 
Mutations
ICGC Data PortalLCOR 
TCGA Data PortalLCOR 
Broad Tumor PortalLCOR
OASIS PortalLCOR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLCOR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLCOR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LCOR
DgiDB (Drug Gene Interaction Database)LCOR
DoCM (Curated mutations)LCOR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LCOR (select a term)
intoGenLCOR
Cancer3DLCOR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
4FNT COLOR=#00004F>Diseases
OMIM607698   
Orphanet
MedgenLCOR
Genetic Testing Registry LCOR
NextProtQ96JN0 [Medical]
TSGene84458
GENETestsLCOR
Target ValidationLCOR
Huge Navigator LCOR [HugePedia]
snp3D : Map Gene to Disease84458
BioCentury BCIQLCOR
ClinGenLCOR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84458
Chemical/Pharm GKB GenePA145148487
Clinical trialLCOR
Miscellaneous
canSAR (ICR)LCOR (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLCOR
EVEXLCOR
GoPubMedLCOR
iHOPLCOR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:15:11 CEST 2017

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