Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LCORL (ligand dependent nuclear receptor corepressor like)

Identity

Alias (NCBI)MLR1
HGNC (Hugo) LCORL
HGNC Alias symbMLR1
FLJ30696
HGNC Previous nameligand dependent nuclear receptor corepressor-like
LocusID (NCBI) 254251
Atlas_Id 65216
Location 4p15.31  [Link to chromosome band 4p15]
Location_base_pair Starts at 17841199 and ends at 18021875 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FRYL (4p11) / LCORL (4p15.31)LCORL (4p15.31) / PKD2 (4q22.1)RBL2 (16q12.2) / LCORL (4p15.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(4;4)(p12;p15) FRYL/LCORL


External links

Nomenclature
HGNC (Hugo)LCORL   30776
Cards
Entrez_Gene (NCBI)LCORL  254251  ligand dependent nuclear receptor corepressor like
AliasesMLR1
GeneCards (Weizmann)LCORL
Ensembl hg19 (Hinxton)ENSG00000178177 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178177 [Gene_View]  ENSG00000178177 [Sequence]  chr4:17841199-18021875 [Contig_View]  LCORL [Vega]
ICGC DataPortalENSG00000178177
TCGA cBioPortalLCORL
AceView (NCBI)LCORL
Genatlas (Paris)LCORL
WikiGenes254251
SOURCE (Princeton)LCORL
Genetics Home Reference (NIH)LCORL
Genomic and cartography
GoldenPath hg38 (UCSC)LCORL  -     chr4:17841199-18021875 -  4p15.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LCORL  -     4p15.31   [Description]    (hg19-Feb_2009)
GoldenPathLCORL - 4p15.31 [CytoView hg19]  LCORL - 4p15.31 [CytoView hg38]
ImmunoBaseENSG00000178177
genome Data Viewer NCBILCORL [Mapview hg19]  
OMIM611799   
Gene and transcription
Genbank (Entrez)AA625769 AI671443 AK054796 AK055258 AK096181
RefSeq transcript (Entrez)NM_001166139 NM_001365658 NM_001365659 NM_001365660 NM_001365661 NM_001365662 NM_001365663 NM_001365665 NM_153686
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LCORL
Alternative Splicing GalleryENSG00000178177
Gene ExpressionLCORL [ NCBI-GEO ]   LCORL [ EBI - ARRAY_EXPRESS ]   LCORL [ SEEK ]   LCORL [ MEM ]
Gene Expression Viewer (FireBrowse)LCORL [ Firebrowse - Broad ]
GenevisibleExpression of LCORL in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)254251
GTEX Portal (Tissue expression)LCORL
Human Protein AtlasENSG00000178177-LCORL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N3X6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N3X6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N3X6
Splice isoforms : SwissVarQ8N3X6
PhosPhoSitePlusQ8N3X6
Domaine pattern : Prosite (Expaxy)HTH_PSQ (PS50960)   
Domains : Interpro (EBI)Homeobox-like_sf    HTH_Psq   
Domain families : Pfam (Sanger)HTH_psq (PF05225)   
Domain families : Pfam (NCBI)pfam05225   
Conserved Domain (NCBI)LCORL
DMDM Disease mutations254251
Blocks (Seattle)LCORL
SuperfamilyQ8N3X6
Human Protein Atlas [tissue]ENSG00000178177-LCORL [tissue]
Peptide AtlasQ8N3X6
HPRD10088
IPIIPI00043716   IPI00874189   IPI00166652   IPI00910217   IPI00967296   
Protein Interaction databases
DIP (DOE-UCLA)Q8N3X6
IntAct (EBI)Q8N3X6
FunCoupENSG00000178177
BioGRIDLCORL
STRING (EMBL)LCORL
ZODIACLCORL
Ontologies - Pathways
QuickGOQ8N3X6
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  
NDEx NetworkLCORL
Atlas of Cancer Signalling NetworkLCORL
Wikipedia pathwaysLCORL
Orthology - Evolution
OrthoDB254251
GeneTree (enSembl)ENSG00000178177
Phylogenetic Trees/Animal Genes : TreeFamLCORL
HOGENOMQ8N3X6
Homologs : HomoloGeneLCORL
Homology/Alignments : Family Browser (UCSC)LCORL
Gene fusions - Rearrangements
Fusion : QuiverLCORL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLCORL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LCORL
dbVarLCORL
ClinVarLCORL
1000_GenomesLCORL 
Exome Variant ServerLCORL
GNOMAD BrowserENSG00000178177
Varsome BrowserLCORL
Genetic variants : HAPMAP254251
Genomic Variants (DGV)LCORL [DGVbeta]
DECIPHERLCORL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLCORL 
Mutations
ICGC Data PortalLCORL 
TCGA Data PortalLCORL 
Broad Tumor PortalLCORL
OASIS PortalLCORL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLCORL  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLCORL
Mutations and Diseases : HGMDLCORL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LCORL
DgiDB (Drug Gene Interaction Database)LCORL
DoCM (Curated mutations)LCORL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LCORL (select a term)
intoGenLCORL
Cancer3DLCORL(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611799   
Orphanet
DisGeNETLCORL
MedgenLCORL
Genetic Testing Registry LCORL
NextProtQ8N3X6 [Medical]
TSGene254251
GENETestsLCORL
Target ValidationLCORL
Huge Navigator LCORL [HugePedia]
snp3D : Map Gene to Disease254251
BioCentury BCIQLCORL
ClinGenLCORL
Clinical trials, drugs, therapy
Protein Interactions : CTD254251
Pharm GKB GenePA145148507
Clinical trialLCORL
Miscellaneous
canSAR (ICR)LCORL (select the gene name)
HarmonizomeLCORL
DataMed IndexLCORL
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLCORL
EVEXLCORL
GoPubMedLCORL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Aug 22 19:15:30 CEST 2020

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.