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LEAP2 (liver expressed antimicrobial peptide 2)

Identity

Alias_namesliver expressed antimicrobial peptide 2
Alias_symbol (synonym)LEAP-2
Other alias
HGNC (Hugo) LEAP2
LocusID (NCBI) 116842
Atlas_Id 51383
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 132209358 and ends at 132210582 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
UQCRQ (5q31.1) / LEAP2 (5q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LEAP2   29571
Cards
Entrez_Gene (NCBI)LEAP2  116842  liver expressed antimicrobial peptide 2
AliasesLEAP-2
GeneCards (Weizmann)LEAP2
Ensembl hg19 (Hinxton)ENSG00000164406 [Gene_View]  chr5:132209358-132210582 [Contig_View]  LEAP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164406 [Gene_View]  chr5:132209358-132210582 [Contig_View]  LEAP2 [Vega]
ICGC DataPortalENSG00000164406
TCGA cBioPortalLEAP2
AceView (NCBI)LEAP2
Genatlas (Paris)LEAP2
WikiGenes116842
SOURCE (Princeton)LEAP2
Genetics Home Reference (NIH)LEAP2
Genomic and cartography
GoldenPath hg19 (UCSC)LEAP2  -     chr5:132209358-132210582 +  5q31.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LEAP2  -     5q31.1   [Description]    (hg38-Dec_2013)
EnsemblLEAP2 - 5q31.1 [CytoView hg19]  LEAP2 - 5q31.1 [CytoView hg38]
Mapping of homologs : NCBILEAP2 [Mapview hg19]  LEAP2 [Mapview hg38]
OMIM611373   
Gene and transcription
Genbank (Entrez)AF143867 AJ306405 AJ409065 AY052782 BC070199
RefSeq transcript (Entrez)NM_052971
RefSeq genomic (Entrez)NC_000005 NC_018916 NG_030340 NT_034772 NW_004929323
Consensus coding sequences : CCDS (NCBI)LEAP2
Cluster EST : UnigeneHs.337588 [ NCBI ]
CGAP (NCI)Hs.337588
Alternative Splicing GalleryENSG00000164406
Gene ExpressionLEAP2 [ NCBI-GEO ]   LEAP2 [ EBI - ARRAY_EXPRESS ]   LEAP2 [ SEEK ]   LEAP2 [ MEM ]
Gene Expression Viewer (FireBrowse)LEAP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116842
GTEX Portal (Tissue expression)LEAP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969E1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969E1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969E1
Splice isoforms : SwissVarQ969E1
PhosPhoSitePlusQ969E1
Domains : Interpro (EBI)LEAP-2   
Domain families : Pfam (Sanger)LEAP-2 (PF07359)   
Domain families : Pfam (NCBI)pfam07359   
Conserved Domain (NCBI)LEAP2
DMDM Disease mutations116842
Blocks (Seattle)LEAP2
PDB (SRS)2L1Q   
PDB (PDBSum)2L1Q   
PDB (IMB)2L1Q   
PDB (RSDB)2L1Q   
Structural Biology KnowledgeBase2L1Q   
SCOP (Structural Classification of Proteins)2L1Q   
CATH (Classification of proteins structures)2L1Q   
SuperfamilyQ969E1
Human Protein AtlasENSG00000164406
Peptide AtlasQ969E1
HPRD17269
IPIIPI00056309   IPI00385251   
Protein Interaction databases
DIP (DOE-UCLA)Q969E1
IntAct (EBI)Q969E1
FunCoupENSG00000164406
BioGRIDLEAP2
STRING (EMBL)LEAP2
ZODIACLEAP2
Ontologies - Pathways
QuickGOQ969E1
Ontology : AmiGOextracellular region  defense response to bacterium  
Ontology : EGO-EBIextracellular region  defense response to bacterium  
NDEx NetworkLEAP2
Atlas of Cancer Signalling NetworkLEAP2
Wikipedia pathwaysLEAP2
Orthology - Evolution
OrthoDB116842
GeneTree (enSembl)ENSG00000164406
Phylogenetic Trees/Animal Genes : TreeFamLEAP2
HOVERGENQ969E1
HOGENOMQ969E1
Homologs : HomoloGeneLEAP2
Homology/Alignments : Family Browser (UCSC)LEAP2
Gene fusions - Rearrangements
Fusion Cancer (Beijing)UQCRQ [5q31.1]  -  LEAP2 [5q31.1]  [FUSC000398]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLEAP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LEAP2
dbVarLEAP2
ClinVarLEAP2
1000_GenomesLEAP2 
Exome Variant ServerLEAP2
ExAC (Exome Aggregation Consortium)LEAP2 (select the gene name)
Genetic variants : HAPMAP116842
Genomic Variants (DGV)LEAP2 [DGVbeta]
DECIPHER (Syndromes)5:132209358-132210582  ENSG00000164406
CONAN: Copy Number AnalysisLEAP2 
Mutations
ICGC Data PortalLEAP2 
TCGA Data PortalLEAP2 
Broad Tumor PortalLEAP2
OASIS PortalLEAP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLEAP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLEAP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LEAP2
DgiDB (Drug Gene Interaction Database)LEAP2
DoCM (Curated mutations)LEAP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LEAP2 (select a term)
intoGenLEAP2
Cancer3DLEAP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611373   
Orphanet
MedgenLEAP2
Genetic Testing Registry LEAP2
NextProtQ969E1 [Medical]
TSGene116842
GENETestsLEAP2
Huge Navigator LEAP2 [HugePedia]
snp3D : Map Gene to Disease116842
BioCentury BCIQLEAP2
ClinGenLEAP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116842
Chemical/Pharm GKB GenePA162393840
Clinical trialLEAP2
Miscellaneous
canSAR (ICR)LEAP2 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLEAP2
EVEXLEAP2
GoPubMedLEAP2
iHOPLEAP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:06:52 CEST 2017

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