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LEMD3 (LEM domain containing 3)

Identity

Other namesMAN1
HGNC (Hugo) LEMD3
LocusID (NCBI) 23592
Location 12q14.3
Location_base_pair Starts at 65563351 and ends at 65642141 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LEMD3   28887
Cards
Entrez_Gene (NCBI)LEMD3  23592  LEM domain containing 3
GeneCards (Weizmann)LEMD3
Ensembl (Hinxton)ENSG00000174106 [Gene_View]  chr12:65563351-65642141 [Contig_View]  LEMD3 [Vega]
ICGC DataPortalENSG00000174106
cBioPortalLEMD3
AceView (NCBI)LEMD3
Genatlas (Paris)LEMD3
WikiGenes23592
SOURCE (Princeton)NM_001167614 NM_014319
Genomic and cartography
GoldenPath (UCSC)LEMD3  -  12q14.3   chr12:65563351-65642141 +  12q14.3   [Description]    (hg19-Feb_2009)
EnsemblLEMD3 - 12q14.3 [CytoView]
Mapping of homologs : NCBILEMD3 [Mapview]
OMIM155950   166700   607844   
Gene and transcription
Genbank (Entrez)AF112299 AK024954 AK295406 AK304317 AK312473
RefSeq transcript (Entrez)NM_001167614 NM_014319
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_016210 NT_029419 NW_001838060 NW_004929384
Consensus coding sequences : CCDS (NCBI)LEMD3
Cluster EST : UnigeneHs.744150 [ NCBI ]
CGAP (NCI)Hs.744150
Alternative Splicing : Fast-db (Paris)GSHG0006803
Alternative Splicing GalleryENSG00000174106
Gene ExpressionLEMD3 [ NCBI-GEO ]     LEMD3 [ SEEK ]   LEMD3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2U8 (Uniprot)
NextProtQ9Y2U8  [Medical]
With graphics : InterProQ9Y2U8
Splice isoforms : SwissVarQ9Y2U8 (Swissvar)
Domaine pattern : Prosite (Expaxy)LEM (PS50954)   
Domains : Interpro (EBI)Inner-Nucl-membr_MAN1 [organisation]   LEM/LEM-like_dom [organisation]   LEM_dom [organisation]   Nucleotide-bd_a/b_plait [organisation]  
Related proteins : CluSTrQ9Y2U8
Domain families : Pfam (Sanger)LEM (PF03020)    MSC (PF09402)   
Domain families : Pfam (NCBI)pfam03020    pfam09402   
Domain families : Smart (EMBL)LEM (SM00540)  
DMDM Disease mutations23592
Blocks (Seattle)Q9Y2U8
PDB (SRS)2CH0   
PDB (PDBSum)2CH0   
PDB (IMB)2CH0   
PDB (RSDB)2CH0   
Human Protein AtlasENSG00000174106 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9Y2U8
HPRD09704
IPIIPI00032491   IPI00954965   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2U8
IntAct (EBI)Q9Y2U8
FunCoupENSG00000174106
BioGRIDLEMD3
InParanoidQ9Y2U8
Interologous Interaction database Q9Y2U8
IntegromeDBLEMD3
STRING (EMBL)LEMD3
Ontologies - Pathways
Ontology : AmiGOnucleotide binding  DNA binding  protein binding  nuclear inner membrane  integral component of nuclear inner membrane  membrane  integral component of membrane  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of BMP signaling pathway  negative regulation of activin receptor signaling pathway  skeletal muscle cell differentiation  regulation of cell cycle  
Ontology : EGO-EBInucleotide binding  DNA binding  protein binding  nuclear inner membrane  integral component of nuclear inner membrane  membrane  integral component of membrane  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of BMP signaling pathway  negative regulation of activin receptor signaling pathway  skeletal muscle cell differentiation  regulation of cell cycle  
Protein Interaction DatabaseLEMD3
Wikipedia pathwaysLEMD3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LEMD3
snp3D : Map Gene to Disease23592
SNP (GeneSNP Utah)LEMD3
SNP : HGBaseLEMD3
Genetic variants : HAPMAPLEMD3
Exome VariantLEMD3
1000_GenomesLEMD3 
ICGC programENSG00000174106 
Somatic Mutations in Cancer : COSMICLEMD3 
CONAN: Copy Number AnalysisLEMD3 
Mutations and Diseases : HGMDLEMD3
Genomic VariantsLEMD3  LEMD3 [DGVbeta]
dbVarLEMD3
ClinVarLEMD3
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM155950    166700    607844   
MedgenLEMD3
GENETestsLEMD3
Disease Genetic AssociationLEMD3
Huge Navigator LEMD3 [HugePedia]  LEMD3 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneLEMD3
Homology/Alignments : Family Browser (UCSC)LEMD3
Phylogenetic Trees/Animal Genes : TreeFamLEMD3
Chemical/Protein Interactions : CTD23592
Chemical/Pharm GKB GenePA134907442
Clinical trialLEMD3
Cancer Resource (Charite)ENSG00000174106
Other databases
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
CoreMineLEMD3
iHOPLEMD3
OncoSearchLEMD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:36:57 CEST 2014

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