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LEPROT (leptin receptor overlapping transcript)

Identity

Alias_symbol (synonym)OBRGRP
OB-RGRP
VPS55
FLJ90360
Other aliasLEPR
HGNC (Hugo) LEPROT
LocusID (NCBI) 54741
Atlas_Id 65234
Location 1p31.3  [Link to chromosome band 1p31]
Location_base_pair Starts at 65886399 and ends at 65901690 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DIS3L (15q22.31) / LEPROT (1p31.3)LEPROT (1p31.3) / CTSS (1q21.3)LEPROT (1p31.3) / IPO9 (1q32.1)
LEPROT (1p31.3) / LEPROT (1p31.3)RAPGEF1 (9q34.13) / LEPROT (1p31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LEPROT   29477
Cards
Entrez_Gene (NCBI)LEPROT  54741  leptin receptor overlapping transcript
AliasesLEPR; OB-RGRP; OBRGRP; VPS55
GeneCards (Weizmann)LEPROT
Ensembl hg19 (Hinxton)ENSG00000213625 [Gene_View]  chr1:65886399-65901690 [Contig_View]  LEPROT [Vega]
Ensembl hg38 (Hinxton)ENSG00000213625 [Gene_View]  chr1:65886399-65901690 [Contig_View]  LEPROT [Vega]
ICGC DataPortalENSG00000213625
TCGA cBioPortalLEPROT
AceView (NCBI)LEPROT
Genatlas (Paris)LEPROT
WikiGenes54741
SOURCE (Princeton)LEPROT
Genetics Home Reference (NIH)LEPROT
Genomic and cartography
GoldenPath hg19 (UCSC)LEPROT  -     chr1:65886399-65901690 +  1p31.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LEPROT  -     1p31.3   [Description]    (hg38-Dec_2013)
EnsemblLEPROT - 1p31.3 [CytoView hg19]  LEPROT - 1p31.3 [CytoView hg38]
Mapping of homologs : NCBILEPROT [Mapview hg19]  LEPROT [Mapview hg38]
OMIM613461   
Gene and transcription
Genbank (Entrez)AK023598 AK026175 AK074841 AK094801 AK130096
RefSeq transcript (Entrez)NM_001198681 NM_001198683 NM_017526
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_015831 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)LEPROT
Cluster EST : UnigeneHs.258228 [ NCBI ]
CGAP (NCI)Hs.258228
Alternative Splicing GalleryENSG00000213625
Gene ExpressionLEPROT [ NCBI-GEO ]   LEPROT [ EBI - ARRAY_EXPRESS ]   LEPROT [ SEEK ]   LEPROT [ MEM ]
Gene Expression Viewer (FireBrowse)LEPROT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54741
GTEX Portal (Tissue expression)LEPROT
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15243   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15243  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15243
Splice isoforms : SwissVarO15243
PhosPhoSitePlusO15243
Domains : Interpro (EBI)VPS55   
Domain families : Pfam (Sanger)Vps55 (PF04133)   
Domain families : Pfam (NCBI)pfam04133   
Conserved Domain (NCBI)LEPROT
DMDM Disease mutations54741
Blocks (Seattle)LEPROT
SuperfamilyO15243
Human Protein AtlasENSG00000213625
Peptide AtlasO15243
HPRD13987
IPIIPI00472452   IPI00977987   IPI00976795   
Protein Interaction databases
DIP (DOE-UCLA)O15243
IntAct (EBI)O15243
FunCoupENSG00000213625
BioGRIDLEPROT
STRING (EMBL)LEPROT
ZODIACLEPROT
Ontologies - Pathways
QuickGOO15243
Ontology : AmiGOGolgi membrane  receptor binding  endosome  Golgi apparatus  endosome membrane  integral component of membrane  negative regulation of JAK-STAT cascade  negative regulation of growth hormone receptor signaling pathway  positive regulation of protein targeting to mitochondrion  negative regulation of protein localization to cell surface  
Ontology : EGO-EBIGolgi membrane  receptor binding  endosome  Golgi apparatus  endosome membrane  integral component of membrane  negative regulation of JAK-STAT cascade  negative regulation of growth hormone receptor signaling pathway  positive regulation of protein targeting to mitochondrion  negative regulation of protein localization to cell surface  
NDEx NetworkLEPROT
Atlas of Cancer Signalling NetworkLEPROT
Wikipedia pathwaysLEPROT
Orthology - Evolution
OrthoDB54741
GeneTree (enSembl)ENSG00000213625
Phylogenetic Trees/Animal Genes : TreeFamLEPROT
HOVERGENO15243
HOGENOMO15243
Homologs : HomoloGeneLEPROT
Homology/Alignments : Family Browser (UCSC)LEPROT
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLEPROT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LEPROT
dbVarLEPROT
ClinVarLEPROT
1000_GenomesLEPROT 
Exome Variant ServerLEPROT
ExAC (Exome Aggregation Consortium)LEPROT (select the gene name)
Genetic variants : HAPMAP54741
Genomic Variants (DGV)LEPROT [DGVbeta]
DECIPHER (Syndromes)1:65886399-65901690  ENSG00000213625
CONAN: Copy Number AnalysisLEPROT 
Mutations
ICGC Data PortalLEPROT 
TCGA Data PortalLEPROT 
Broad Tumor PortalLEPROT
OASIS PortalLEPROT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLEPROT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLEPROT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LEPROT
DgiDB (Drug Gene Interaction Database)LEPROT
DoCM (Curated mutations)LEPROT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LEPROT (select a term)
intoGenLEPROT
Cancer3DLEPROT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613461   
Orphanet
MedgenLEPROT
Genetic Testing Registry LEPROT
NextProtO15243 [Medical]
TSGene54741
GENETestsLEPROT
Huge Navigator LEPROT [HugePedia]
snp3D : Map Gene to Disease54741
BioCentury BCIQLEPROT
ClinGenLEPROT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54741
Chemical/Pharm GKB GenePA134913422
Clinical trialLEPROT
Miscellaneous
canSAR (ICR)LEPROT (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLEPROT
EVEXLEPROT
GoPubMedLEPROT
iHOPLEPROT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:10:58 CET 2017

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