LEPROTL1 (leptin receptor overlapping transcript like 1)

2021-06-01  

Identity

HGNC
LEPROTL1
LOCATION
8p12
LOCUSID
23484
ALIAS
HSPC112,Vps55,my047

Other Information

Locus ID:

NCBI: 23484
MIM: 607338
HGNC: 6555
Ensembl: ENSG00000104660

Variants:

dbSNP: 23484
ClinVar: 23484
TCGA: ENSG00000104660
COSMIC: LEPROTL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104660ENST00000321250O95214
ENSG00000104660ENST00000321250Q6FHL7
ENSG00000104660ENST00000442880C9JVM4
ENSG00000104660ENST00000518001E5RIQ0
ENSG00000104660ENST00000518192E5RJS9
ENSG00000104660ENST00000519466H0YBC1
ENSG00000104660ENST00000520682E5RHU8
ENSG00000104660ENST00000520739E5RIL0
ENSG00000104660ENST00000523116O95214
ENSG00000104660ENST00000650149A0A3B3IS19

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.38
199070802009LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice.24
198760042010Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study.11
297205722018Endospanin-2 enhances skeletal muscle energy metabolism and running endurance capacity.1
309434672019Promoter Mutation Analysis of LEPROTL1 Gene in Acute Leukemias and Solid Tumors.0

Citation

Dessen P

LEPROTL1 (leptin receptor overlapping transcript like 1)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58379/leprotl1