LETMD1 (LETM1 domain containing 1)

2003-02-01  

Identity

HGNC
LETMD1
LOCATION
12q13.12
LOCUSID
25875
ALIAS
1110019O13Rik,HCCR,HCCR-1,HCCR-2,HCCR1,HCCR2,HCRR-2,SLC55A3

Other Information

Locus ID:

NCBI: 25875
HGNC: 24241
Ensembl: ENSG00000050426

Variants:

dbSNP: 25875
ClinVar: 25875
TCGA: ENSG00000050426
COSMIC: LETMD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000050426ENST00000262055Q6P1Q0
ENSG00000050426ENST00000262055A0A384P5D7
ENSG00000050426ENST00000380135F8W6J0
ENSG00000050426ENST00000418425Q6P1Q0
ENSG00000050426ENST00000547008F8W1Z2
ENSG00000050426ENST00000547256H0YH93
ENSG00000050426ENST00000547318F8WCD9
ENSG00000050426ENST00000547555F8VR35
ENSG00000050426ENST00000547660F8VR33
ENSG00000050426ENST00000548209F8VPY5
ENSG00000050426ENST00000548251F8W0R0
ENSG00000050426ENST00000548401F8VQE7
ENSG00000050426ENST00000549340F8VVQ3
ENSG00000050426ENST00000549686F8W1U1
ENSG00000050426ENST00000550100Q6P1Q0
ENSG00000050426ENST00000550442F8VTR1
ENSG00000050426ENST00000550755F8VUZ8
ENSG00000050426ENST00000550814F8VS60
ENSG00000050426ENST00000550929Q6P1Q0
ENSG00000050426ENST00000551261F8VXQ4
ENSG00000050426ENST00000551477F8VZA2
ENSG00000050426ENST00000551931H0YIV5
ENSG00000050426ENST00000552739F8VP71
ENSG00000050426ENST00000553043H0YHF4

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
128790132003Identification and differential expression of novel human cervical cancer oncogene HCCR-2 in human cancers and its involvement in p53 stabilization.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
169492182006The phosphatidylinositol 3-kinase/Akt pathway regulates the HCCR-1 oncogene expression.14
146914482004Transgenic mouse model for breast cancer: induction of breast cancer in novel oncogene HCCR-2 transgenic mice.13
162783902005The HCCR oncoprotein as a biomarker for human breast cancer.13
204234852010Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells.10
205911352010Transdifferentiation-inducing HCCR-1 oncogene.9
192082632009Oncoprotein HCCR-1 expression in breast cancer is well correlated with known breast cancer prognostic factors including the HER2 overexpression, p53 mutation, and ER/PR status.8
180454962007HCCR-1, a novel oncogene, encodes a mitochondrial outer membrane protein and suppresses the UVC-induced apoptosis.7
120617252002Isolation of novel differentially expressed genes related to human glioma using cDNA microarray and characterizations of two novel full-length genes.4

Citation

Dessen P

LETMD1 (LETM1 domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40797/letmd1