LGALS12 (galectin 12)

2015-03-01  

Identity

HGNC
LGALS12
LOCATION
11q12.3
LOCUSID
85329
ALIAS
GAL12,GRIP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 85329
MIM: 606096
HGNC: 15788
Ensembl: ENSG00000133317

Variants:

dbSNP: 85329
ClinVar: 85329
TCGA: ENSG00000133317
COSMIC: LGALS12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133317ENST00000255684Q96DT0
ENSG00000133317ENST00000340246Q96DT0
ENSG00000133317ENST00000394618Q96DT0
ENSG00000133317ENST00000415491Q96DT0
ENSG00000133317ENST00000425950Q96DT0
ENSG00000133317ENST00000674247A0A140VK26

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
151311272004Galectin-12 is required for adipogenic signaling and adipocyte differentiation.21
259532642015Expression profiling of cancer-related galectins in acute myeloid leukemia.4
272565732016Galectin-12 inhibits granulocytic differentiation of human NB4 promyelocytic leukemia cells while promoting lipogenesis.2
290987692017Analyzing epigenetic control of galectin expression indicates silencing of galectin-12 by promoter methylation in colorectal cancer.1
309359482019Deciphering the galectin-12 protein interactome reveals a major impact of galectin-12 on glutamine anaplerosis in colon cancer cells.1

Citation

Dessen P

LGALS12 (galectin 12)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55659/lgals12