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LGALS2 (lectin, galactoside binding soluble 2)

Identity

Alias_nameslectin
Alias_symbol (synonym)HL14
Other alias
HGNC (Hugo) LGALS2
LocusID (NCBI) 3957
Atlas_Id 49983
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 37966253 and ends at 37976024 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RBFOX2 (22q12.3) / LGALS2 (22q13.1)SSBP2 (5q14.1) / LGALS2 (22q13.1)RBFOX2 22q12.3 / LGALS2 22q13.1
SSBP2 5q14.1 / LGALS2 22q13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LGALS2   6562
Cards
Entrez_Gene (NCBI)LGALS2  3957  lectin, galactoside binding soluble 2
AliasesHL14
GeneCards (Weizmann)LGALS2
Ensembl hg19 (Hinxton)ENSG00000100079 [Gene_View]  chr22:37966253-37976024 [Contig_View]  LGALS2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100079 [Gene_View]  chr22:37966253-37976024 [Contig_View]  LGALS2 [Vega]
ICGC DataPortalENSG00000100079
TCGA cBioPortalLGALS2
AceView (NCBI)LGALS2
Genatlas (Paris)LGALS2
WikiGenes3957
SOURCE (Princeton)LGALS2
Genetics Home Reference (NIH)LGALS2
Genomic and cartography
GoldenPath hg19 (UCSC)LGALS2  -     chr22:37966253-37976024 -  22q13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LGALS2  -     22q13.1   [Description]    (hg38-Dec_2013)
EnsemblLGALS2 - 22q13.1 [CytoView hg19]  LGALS2 - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBILGALS2 [Mapview hg19]  LGALS2 [Mapview hg38]
OMIM150571   608446   
Gene and transcription
Genbank (Entrez)BC029063 BC059782 CD701729 CR456512 CR541972
RefSeq transcript (Entrez)NM_006498
RefSeq genomic (Entrez)NC_000022 NC_018933 NG_012096 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)LGALS2
Cluster EST : UnigeneHs.531776 [ NCBI ]
CGAP (NCI)Hs.531776
Alternative Splicing GalleryENSG00000100079
Gene ExpressionLGALS2 [ NCBI-GEO ]   LGALS2 [ EBI - ARRAY_EXPRESS ]   LGALS2 [ SEEK ]   LGALS2 [ MEM ]
Gene Expression Viewer (FireBrowse)LGALS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3957
GTEX Portal (Tissue expression)LGALS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05162   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05162  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05162
Splice isoforms : SwissVarP05162
PhosPhoSitePlusP05162
Domaine pattern : Prosite (Expaxy)GALECTIN (PS51304)   
Domains : Interpro (EBI)ConA-like_dom    Galectin_CRD   
Domain families : Pfam (Sanger)Gal-bind_lectin (PF00337)   
Domain families : Pfam (NCBI)pfam00337   
Domain families : Smart (EMBL)Gal-bind_lectin (SM00908)  GLECT (SM00276)  
Conserved Domain (NCBI)LGALS2
DMDM Disease mutations3957
Blocks (Seattle)LGALS2
PDB (SRS)1HLC   
PDB (PDBSum)1HLC   
PDB (IMB)1HLC   
PDB (RSDB)1HLC   
Structural Biology KnowledgeBase1HLC   
SCOP (Structural Classification of Proteins)1HLC   
CATH (Classification of proteins structures)1HLC   
SuperfamilyP05162
Human Protein AtlasENSG00000100079
Peptide AtlasP05162
HPRD08859
IPIIPI00007242   IPI00879321   
Protein Interaction databases
DIP (DOE-UCLA)P05162
IntAct (EBI)P05162
FunCoupENSG00000100079
BioGRIDLGALS2
STRING (EMBL)LGALS2
ZODIACLGALS2
Ontologies - Pathways
QuickGOP05162
Ontology : AmiGOprotein binding  galactoside binding  carbohydrate binding  
Ontology : EGO-EBIprotein binding  galactoside binding  carbohydrate binding  
NDEx NetworkLGALS2
Atlas of Cancer Signalling NetworkLGALS2
Wikipedia pathwaysLGALS2
Orthology - Evolution
OrthoDB3957
GeneTree (enSembl)ENSG00000100079
Phylogenetic Trees/Animal Genes : TreeFamLGALS2
HOVERGENP05162
HOGENOMP05162
Homologs : HomoloGeneLGALS2
Homology/Alignments : Family Browser (UCSC)LGALS2
Gene fusions - Rearrangements
Fusion : MitelmanRBFOX2/LGALS2 [22q12.3/22q13.1]  [t(22;22)(q12;q13)]  
Fusion : MitelmanSSBP2/LGALS2 [5q14.1/22q13.1]  [t(5;22)(q14;q13)]  
Fusion: TCGARBFOX2 22q12.3 LGALS2 22q13.1 GBM
Fusion: TCGASSBP2 5q14.1 LGALS2 22q13.1 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLGALS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LGALS2
dbVarLGALS2
ClinVarLGALS2
1000_GenomesLGALS2 
Exome Variant ServerLGALS2
ExAC (Exome Aggregation Consortium)LGALS2 (select the gene name)
Genetic variants : HAPMAP3957
Genomic Variants (DGV)LGALS2 [DGVbeta]
DECIPHER (Syndromes)22:37966253-37976024  ENSG00000100079
CONAN: Copy Number AnalysisLGALS2 
Mutations
ICGC Data PortalLGALS2 
TCGA Data PortalLGALS2 
Broad Tumor PortalLGALS2
OASIS PortalLGALS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLGALS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLGALS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LGALS2
DgiDB (Drug Gene Interaction Database)LGALS2
DoCM (Curated mutations)LGALS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LGALS2 (select a term)
intoGenLGALS2
Cancer3DLGALS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM150571    608446   
Orphanet
MedgenLGALS2
Genetic Testing Registry LGALS2
NextProtP05162 [Medical]
TSGene3957
GENETestsLGALS2
Huge Navigator LGALS2 [HugePedia]
snp3D : Map Gene to Disease3957
BioCentury BCIQLGALS2
ClinGenLGALS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3957
Chemical/Pharm GKB GenePA164741896
Clinical trialLGALS2
Miscellaneous
canSAR (ICR)LGALS2 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLGALS2
EVEXLGALS2
GoPubMedLGALS2
iHOPLGALS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:12:43 CET 2017

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