LGALS7 (galectin 7)

2003-06-01  

Identity

HGNC
LGALS7
LOCATION
19q13.2
LOCUSID
3963
ALIAS
GAL7,LGALS7A

Other Information

Locus ID:

NCBI: 3963
MIM: 600615
HGNC: 6568
Ensembl: ENSG00000205076

Variants:

dbSNP: 3963
ClinVar: 3963
TCGA: ENSG00000205076
COSMIC: LGALS7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205076ENST00000378626P47929
ENSG00000205076ENST00000599035M0R281

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203827002010Overexpression of galectin-7, a myoepithelial cell marker, enhances spontaneous metastasis of breast cancer cells.34
239859922013Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer.26
136798662003Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells.25
212890922011Mitochondrial proteomic approach reveals galectin-7 as a novel BCL-2 binding protein in human cells.21
205466282010Identification of galectin-7 as a potential biomarker for esophageal squamous cell carcinoma by proteomic analysis.17
167887632006Galectin 7 (p53-induced gene 1): a new prognostic predictor of recurrence and survival in stage IV hypopharyngeal cancer.16
216771442011Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.16
275908972017Tissue- and cell-specific localization of galectins, β-galactose-binding animal lectins, and their potential functions in health and disease.16
252771992014Expression and functions of galectin-7 in ovarian cancer.15
235647972013Clinical significance of galectin-7 in epithelial ovarian cancer.14

Citation

Dessen P

LGALS7 (galectin 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41145/lgals7