LGI3 (leucine rich repeat LGI family member 3)

2016-05-01  

Identity

HGNC
LOCATION
8p21.3
LOCUSID
ALIAS
LGIL4
FUSION GENES

Other Information

Locus ID:

NCBI: 203190
MIM: 608302
HGNC: 18711
Ensembl: ENSG00000168481

Variants:

dbSNP: 203190
ClinVar: 203190
TCGA: ENSG00000168481
COSMIC: LGI3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168481ENST00000306317Q8N145
ENSG00000168481ENST00000424267Q8N145
ENSG00000168481ENST00000517694H0YAP4
ENSG00000168481ENST00000518365E5RIV5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
LGI-ADAM interactionsREACTOMER-HSA-5682910

References

Pubmed IDYearTitleCitations
238152302013Leucine-rich glioma inactivated 3 promotes HaCaT keratinocyte migration.6
249035532014Leucine-rich glioma inactivated 3 is a melanogenic cytokine in human skin.4
292573042018Leucine-rich glioma inactivated 3: Integrative analyses reveal its potential prognostic role in cancer.1
300918032018LGI3 promotes human keratinocyte differentiation via the Akt pathway.1

Citation

Dessen P

LGI3 (leucine rich repeat LGI family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55756/lgi3