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LGI3 (leucine rich repeat LGI family member 3)

Identity

Alias_namesleucine-rich repeat LGI family
Other aliasLGIL4
HGNC (Hugo) LGI3
LocusID (NCBI) 203190
Atlas_Id 55756
Location 8p21.3  [Link to chromosome band 8p21]
Location_base_pair Starts at 22146830 and ends at 22156831 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FBXO7 (22q12.3) / LGI3 (8p21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LGI3   18711
Cards
Entrez_Gene (NCBI)LGI3  203190  leucine rich repeat LGI family member 3
AliasesLGIL4
GeneCards (Weizmann)LGI3
Ensembl hg19 (Hinxton)ENSG00000168481 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168481 [Gene_View]  chr8:22146830-22156831 [Contig_View]  LGI3 [Vega]
ICGC DataPortalENSG00000168481
TCGA cBioPortalLGI3
AceView (NCBI)LGI3
Genatlas (Paris)LGI3
WikiGenes203190
SOURCE (Princeton)LGI3
Genetics Home Reference (NIH)LGI3
Genomic and cartography
GoldenPath hg38 (UCSC)LGI3  -     chr8:22146830-22156831 -  8p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LGI3  -     8p21.3   [Description]    (hg19-Feb_2009)
EnsemblLGI3 - 8p21.3 [CytoView hg19]  LGI3 - 8p21.3 [CytoView hg38]
Mapping of homologs : NCBILGI3 [Mapview hg19]  LGI3 [Mapview hg38]
OMIM608302   
Gene and transcription
Genbank (Entrez)AF467956 AJ487518 AJ487961 AK090946 AY358116
RefSeq transcript (Entrez)NM_139278
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LGI3
Cluster EST : UnigeneHs.33470 [ NCBI ]
CGAP (NCI)Hs.33470
Alternative Splicing GalleryENSG00000168481
Gene ExpressionLGI3 [ NCBI-GEO ]   LGI3 [ EBI - ARRAY_EXPRESS ]   LGI3 [ SEEK ]   LGI3 [ MEM ]
Gene Expression Viewer (FireBrowse)LGI3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)203190
GTEX Portal (Tissue expression)LGI3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N145   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N145  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N145
Splice isoforms : SwissVarQ8N145
PhosPhoSitePlusQ8N145
Domaine pattern : Prosite (Expaxy)EAR (PS50912)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    EAR    EPTP    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    Quinoprot_gluc/sorb_DH   
Domain families : Pfam (Sanger)EPTP (PF03736)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam03736    pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)LGI3
DMDM Disease mutations203190
Blocks (Seattle)LGI3
SuperfamilyQ8N145
Human Protein AtlasENSG00000168481
Peptide AtlasQ8N145
HPRD06432
IPIIPI00166075   IPI00915426   IPI00984972   IPI00974159   
Protein Interaction databases
DIP (DOE-UCLA)Q8N145
IntAct (EBI)Q8N145
FunCoupENSG00000168481
BioGRIDLGI3
STRING (EMBL)LGI3
ZODIACLGI3
Ontologies - Pathways
QuickGOQ8N145
Ontology : AmiGOcatalytic activity  extracellular region  exocytosis  synaptic vesicle  regulation of exocytosis  cell junction  neuron projection  
Ontology : EGO-EBIcatalytic activity  extracellular region  exocytosis  synaptic vesicle  regulation of exocytosis  cell junction  neuron projection  
NDEx NetworkLGI3
Atlas of Cancer Signalling NetworkLGI3
Wikipedia pathwaysLGI3
Orthology - Evolution
OrthoDB203190
GeneTree (enSembl)ENSG00000168481
Phylogenetic Trees/Animal Genes : TreeFamLGI3
HOVERGENQ8N145
HOGENOMQ8N145
Homologs : HomoloGeneLGI3
Homology/Alignments : Family Browser (UCSC)LGI3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLGI3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LGI3
dbVarLGI3
ClinVarLGI3
1000_GenomesLGI3 
Exome Variant ServerLGI3
ExAC (Exome Aggregation Consortium)LGI3 (select the gene name)
Genetic variants : HAPMAP203190
Genomic Variants (DGV)LGI3 [DGVbeta]
DECIPHERLGI3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLGI3 
Mutations
ICGC Data PortalLGI3 
TCGA Data PortalLGI3 
Broad Tumor PortalLGI3
OASIS PortalLGI3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLGI3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLGI3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LGI3
DgiDB (Drug Gene Interaction Database)LGI3
DoCM (Curated mutations)LGI3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LGI3 (select a term)
intoGenLGI3
Cancer3DLGI3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608302   
Orphanet
MedgenLGI3
Genetic Testing Registry LGI3
NextProtQ8N145 [Medical]
TSGene203190
GENETestsLGI3
Target ValidationLGI3
Huge Navigator LGI3 [HugePedia]
snp3D : Map Gene to Disease203190
BioCentury BCIQLGI3
ClinGenLGI3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD203190
Chemical/Pharm GKB GenePA38655
Clinical trialLGI3
Miscellaneous
canSAR (ICR)LGI3 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLGI3
EVEXLGI3
GoPubMedLGI3
iHOPLGI3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:15:21 CEST 2017

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