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LGR6 (leucine rich repeat containing G protein-coupled receptor 6)

Identity

Other aliasGPCR
VTS20631
HGNC (Hugo) LGR6
LocusID (NCBI) 59352
Atlas_Id 57032
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 202193990 and ends at 202319761 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LGR6 (1q32.1) / GPR37L1 (1q32.1)PPP1R12B (1q32.1) / LGR6 (1q32.1)RABGAP1L (1q25.1) / LGR6 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LGR6   19719
Cards
Entrez_Gene (NCBI)LGR6  59352  leucine rich repeat containing G protein-coupled receptor 6
AliasesGPCR; VTS20631
GeneCards (Weizmann)LGR6
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr1:202193990-202319761 [Contig_View]  LGR6 [Vega]
TCGA cBioPortalLGR6
AceView (NCBI)LGR6
Genatlas (Paris)LGR6
WikiGenes59352
SOURCE (Princeton)LGR6
Genetics Home Reference (NIH)LGR6
Genomic and cartography
GoldenPath hg38 (UCSC)LGR6  -     chr1:202193990-202319761 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LGR6  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblLGR6 - 1q32.1 [CytoView hg19]  LGR6 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBILGR6 [Mapview hg19]  LGR6 [Mapview hg38]
OMIM606653   
Gene and transcription
Genbank (Entrez)AB049405 AF088074 AF190501 AK027377 AK123055
RefSeq transcript (Entrez)NM_001017403 NM_001017404 NM_021636
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LGR6
Cluster EST : UnigeneHs.497402 [ NCBI ]
CGAP (NCI)Hs.497402
Gene ExpressionLGR6 [ NCBI-GEO ]   LGR6 [ EBI - ARRAY_EXPRESS ]   LGR6 [ SEEK ]   LGR6 [ MEM ]
Gene Expression Viewer (FireBrowse)LGR6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)59352
GTEX Portal (Tissue expression)LGR6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HBX8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HBX8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HBX8
Splice isoforms : SwissVarQ9HBX8
PhosPhoSitePlusQ9HBX8
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)GPCR_Rhodpsn    Gphrmn_rcpt_fam    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)LGR6
DMDM Disease mutations59352
Blocks (Seattle)LGR6
SuperfamilyQ9HBX8
Peptide AtlasQ9HBX8
IPIIPI00151908   IPI00479360   IPI00514691   IPI00640302   IPI00514116   IPI00964672   
Protein Interaction databases
DIP (DOE-UCLA)Q9HBX8
IntAct (EBI)Q9HBX8
BioGRIDLGR6
STRING (EMBL)LGR6
ZODIACLGR6
Ontologies - Pathways
QuickGOQ9HBX8
Ontology : AmiGOtransmembrane signaling receptor activity  G-protein coupled receptor activity  protein binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  Wnt signaling pathway  positive regulation of Wnt signaling pathway  positive regulation of cell migration  vesicle  trans-Golgi network membrane  positive regulation of canonical Wnt signaling pathway  bone regeneration  
Ontology : EGO-EBItransmembrane signaling receptor activity  G-protein coupled receptor activity  protein binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  Wnt signaling pathway  positive regulation of Wnt signaling pathway  positive regulation of cell migration  vesicle  trans-Golgi network membrane  positive regulation of canonical Wnt signaling pathway  bone regeneration  
NDEx NetworkLGR6
Atlas of Cancer Signalling NetworkLGR6
Wikipedia pathwaysLGR6
Orthology - Evolution
OrthoDB59352
Phylogenetic Trees/Animal Genes : TreeFamLGR6
HOVERGENQ9HBX8
HOGENOMQ9HBX8
Homologs : HomoloGeneLGR6
Homology/Alignments : Family Browser (UCSC)LGR6
Gene fusions - Rearrangements
Fusion: Tumor Portal LGR6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLGR6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LGR6
dbVarLGR6
ClinVarLGR6
1000_GenomesLGR6 
Exome Variant ServerLGR6
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP59352
Genomic Variants (DGV)LGR6 [DGVbeta]
DECIPHERLGR6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLGR6 
FOOT COLOR=#00004F>Mutations
ICGC Data PortalLGR6 
TCGA Data PortalLGR6 
Broad Tumor PortalLGR6
OASIS PortalLGR6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLGR6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLGR6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LGR6
DgiDB (Drug Gene Interaction Database)LGR6
DoCM (Curated mutations)LGR6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LGR6 (select a term)
intoGenLGR6
Cancer3DLGR6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606653   
Orphanet
MedgenLGR6
Genetic Testing Registry LGR6
NextProtQ9HBX8 [Medical]
TSGene59352
GENETestsLGR6
Target ValidationLGR6
Huge Navigator LGR6 [HugePedia]
snp3D : Map Gene to Disease59352
BioCentury BCIQLGR6
ClinGenLGR6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD59352
Chemical/Pharm GKB GenePA134927114
Clinical trialLGR6
Miscellaneous
canSAR (ICR)LGR6 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLGR6
EVEXLGR6
GoPubMedLGR6
iHOPLGR6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:56:19 CET 2017

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