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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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LHB (luteinizing hormone beta polypeptide)

Identity

Other namesCGB4
LSH-B
hLHB
HGNC (Hugo) LHB
LocusID (NCBI) 3972
Location 19q13.33
Location_base_pair Starts at 49519237 and ends at 49520347 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LHB   6584
Cards
Entrez_Gene (NCBI)LHB  3972  luteinizing hormone beta polypeptide
GeneCards (Weizmann)LHB
Ensembl hg19 (Hinxton)ENSG00000104826 [Gene_View]  chr19:49519237-49520347 [Contig_View]  LHB [Vega]
Ensembl hg38 (Hinxton)ENSG00000104826 [Gene_View]  chr19:49519237-49520347 [Contig_View]  LHB [Vega]
ICGC DataPortalENSG00000104826
cBioPortalLHB
AceView (NCBI)LHB
Genatlas (Paris)LHB
WikiGenes3972
SOURCE (Princeton)LHB
Genomic and cartography
GoldenPath hg19 (UCSC)LHB  -     chr19:49519237-49520347 -  19q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LHB  -     19q13.33   [Description]    (hg38-Dec_2013)
EnsemblLHB - 19q13.33 [CytoView hg19]  LHB - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBILHB [Mapview hg19]  LHB [Mapview hg38]
OMIM152780   
Gene and transcription
Genbank (Entrez)BC160107
RefSeq transcript (Entrez)NM_000894
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_011464 NG_033041 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)LHB
Cluster EST : UnigeneHs.154704 [ NCBI ]
CGAP (NCI)Hs.154704
Alternative Splicing : Fast-db (Paris)GSHG0040153
Alternative Splicing GalleryENSG00000104826
Gene ExpressionLHB [ NCBI-GEO ]     LHB [ SEEK ]   LHB [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01229 (Uniprot)
NextProtP01229  [Medical]
With graphics : InterProP01229
Splice isoforms : SwissVarP01229 (Swissvar)
Domaine pattern : Prosite (Expaxy)GLYCO_HORMONE_BETA_1 (PS00261)    GLYCO_HORMONE_BETA_2 (PS00689)   
Domains : Interpro (EBI)Cystine-knot_cytokine    Glyco_hormone_CN    Gonadotropin_bsu    Gonadotropin_bsu_CS   
Related proteins : CluSTrP01229
Domain families : Pfam (Sanger)Cys_knot (PF00007)   
Domain families : Pfam (NCBI)pfam00007   
Domain families : Smart (EMBL)GHB (SM00068)  
DMDM Disease mutations3972
Blocks (Seattle)P01229
PDB (SRS)1M92   
PDB (PDBSum)1M92   
PDB (IMB)1M92   
PDB (RSDB)1M92   
Human Protein AtlasENSG00000104826
Peptide AtlasP01229
HPRD01072
IPIIPI00000854   IPI00937264   
Protein Interaction databases
DIP (DOE-UCLA)P01229
IntAct (EBI)P01229
FunCoupENSG00000104826
BioGRIDLHB
IntegromeDBLHB
STRING (EMBL)LHB
Ontologies - Pathways
QuickGOP01229
Ontology : AmiGOreceptor binding  hormone activity  extracellular region  progesterone biosynthetic process  signal transduction  cell-cell signaling  male gonad development  peptide hormone processing  cellular protein metabolic process  extracellular exosome  
Ontology : EGO-EBIreceptor binding  hormone activity  extracellular region  progesterone biosynthetic process  signal transduction  cell-cell signaling  male gonad development  peptide hormone processing  cellular protein metabolic process  extracellular exosome  
Pathways : KEGGNeuroactive ligand-receptor interaction    GnRH signaling pathway    Ovarian steroidogenesis    Prolactin signaling pathway   
Protein Interaction DatabaseLHB
DoCM (Curated mutations)LHB
Wikipedia pathwaysLHB
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerLHB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LHB
dbVarLHB
ClinVarLHB
1000_GenomesLHB 
Exome Variant ServerLHB
SNP (GeneSNP Utah)LHB
SNP : HGBaseLHB
Genetic variants : HAPMAPLHB
Genomic Variants (DGV)LHB [DGVbeta]
Mutations
ICGC Data PortalENSG00000104826 
Somatic Mutations in Cancer : COSMICLHB 
CONAN: Copy Number AnalysisLHB 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:49519237-49520347
Mutations and Diseases : HGMDLHB
OMIM152780   
MedgenLHB
NextProtP01229 [Medical]
GENETestsLHB
Disease Genetic AssociationLHB
Huge Navigator LHB [HugePedia]  LHB [HugeCancerGEM]
snp3D : Map Gene to Disease3972
DGIdb (Drug Gene Interaction db)LHB
General knowledge
Homologs : HomoloGeneLHB
Homology/Alignments : Family Browser (UCSC)LHB
Phylogenetic Trees/Animal Genes : TreeFamLHB
Chemical/Protein Interactions : CTD3972
Chemical/Pharm GKB GenePA30356
Clinical trialLHB
Cancer Resource (Charite)ENSG00000104826
Other databases
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
CoreMineLHB
GoPubMedLHB
iHOPLHB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:50:21 CET 2015

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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.