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LHFPL2 (LHFPL tetraspan subfamily member 2)

Identity

Alias (NCBI)-
HGNC (Hugo) LHFPL2
HGNC Alias symbKIAA0206
HGNC Previous namelipoma HMGIC fusion partner-like 2
LocusID (NCBI) 10184
Atlas_Id 56266
Location 5q14.1  [Link to chromosome band 5q14]
Location_base_pair Starts at 78485230 and ends at 78648772 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HIST1H2AC (6p22.2) / LHFPL2 (5q14.1)KCNMA1 (10q22.3) / LHFPL2 (5q14.1)LHFPL2 (5q14.1) / ANXA2 (15q22.2)
LHFPL2 (5q14.1) / CRK (17p13.3)LHFPL2 (5q14.1) / HIST1H2AC (6p22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LHFPL2   6588
Cards
Entrez_Gene (NCBI)LHFPL2    LHFPL tetraspan subfamily member 2
Aliases
GeneCards (Weizmann)LHFPL2
Ensembl hg19 (Hinxton)ENSG00000145685 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145685 [Gene_View]  ENSG00000145685 [Sequence]  chr5:78485230-78648772 [Contig_View]  LHFPL2 [Vega]
ICGC DataPortalENSG00000145685
TCGA cBioPortalLHFPL2
AceView (NCBI)LHFPL2
Genatlas (Paris)LHFPL2
SOURCE (Princeton)LHFPL2
Genetics Home Reference (NIH)LHFPL2
Genomic and cartography
GoldenPath hg38 (UCSC)LHFPL2  -     chr5:78485230-78648772 -  5q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LHFPL2  -     5q14.1   [Description]    (hg19-Feb_2009)
GoldenPathLHFPL2 - 5q14.1 [CytoView hg19]  LHFPL2 - 5q14.1 [CytoView hg38]
ImmunoBaseENSG00000145685
Genome Data Viewer NCBILHFPL2 [Mapview hg19]  
OMIM609718   
Gene and transcription
Genbank (Entrez)AK091868 AK125227 AY309920 BC136335 BC136336
RefSeq transcript (Entrez)NM_005779
Consensus coding sequences : CCDS (NCBI)LHFPL2
Gene ExpressionLHFPL2 [ NCBI-GEO ]   LHFPL2 [ EBI - ARRAY_EXPRESS ]   LHFPL2 [ SEEK ]   LHFPL2 [ MEM ]
Gene Expression Viewer (FireBrowse)LHFPL2 [ Firebrowse - Broad ]
GenevisibleExpression of LHFPL2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10184
GTEX Portal (Tissue expression)LHFPL2
Human Protein AtlasENSG00000145685-LHFPL2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZUX7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZUX7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZUX7
PhosPhoSitePlusQ6ZUX7
Domains : Interpro (EBI)LHFPL   
Domain families : Pfam (Sanger)L_HMGIC_fpl (PF10242)   
Domain families : Pfam (NCBI)pfam10242   
Conserved Domain (NCBI)LHFPL2
SuperfamilyQ6ZUX7
AlphaFold pdb e-kbQ6ZUX7   
Human Protein Atlas [tissue]ENSG00000145685-LHFPL2 [tissue]
HPRD17272
Protein Interaction databases
DIP (DOE-UCLA)Q6ZUX7
IntAct (EBI)Q6ZUX7
BioGRIDLHFPL2
STRING (EMBL)LHFPL2
ZODIACLHFPL2
Ontologies - Pathways
QuickGOQ6ZUX7
Ontology : AmiGOplatelet degranulation  molecular_function  protein binding  cellular_component  plasma membrane  single fertilization  biological_process  membrane  integral component of membrane  platelet alpha granule membrane  development of primary female sexual characteristics  development of primary male sexual characteristics  positive regulation of fertilization  
Ontology : EGO-EBIplatelet degranulation  molecular_function  protein binding  cellular_component  plasma membrane  single fertilization  biological_process  membrane  integral component of membrane  platelet alpha granule membrane  development of primary female sexual characteristics  development of primary male sexual characteristics  positive regulation of fertilization  
NDEx NetworkLHFPL2
Atlas of Cancer Signalling NetworkLHFPL2
Wikipedia pathwaysLHFPL2
Orthology - Evolution
OrthoDB10184
GeneTree (enSembl)ENSG00000145685
Phylogenetic Trees/Animal Genes : TreeFamLHFPL2
Homologs : HomoloGeneLHFPL2
Homology/Alignments : Family Browser (UCSC)LHFPL2
Gene fusions - Rearrangements
Fusion : QuiverLHFPL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLHFPL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LHFPL2
dbVarLHFPL2
ClinVarLHFPL2
MonarchLHFPL2
1000_GenomesLHFPL2 
Exome Variant ServerLHFPL2
GNOMAD BrowserENSG00000145685
Varsome BrowserLHFPL2
ACMGLHFPL2 variants
VarityQ6ZUX7
Genomic Variants (DGV)LHFPL2 [DGVbeta]
DECIPHERLHFPL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLHFPL2 
Mutations
ICGC Data PortalLHFPL2 
TCGA Data PortalLHFPL2 
Broad Tumor PortalLHFPL2
OASIS PortalLHFPL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLHFPL2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLHFPL2
Mutations and Diseases : HGMDLHFPL2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLHFPL2
DgiDB (Drug Gene Interaction Database)LHFPL2
DoCM (Curated mutations)LHFPL2
CIViC (Clinical Interpretations of Variants in Cancer)LHFPL2
Cancer3DLHFPL2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609718   
Orphanet
DisGeNETLHFPL2
MedgenLHFPL2
Genetic Testing Registry LHFPL2
NextProtQ6ZUX7 [Medical]
GENETestsLHFPL2
Target ValidationLHFPL2
Huge Navigator LHFPL2 [HugePedia]
ClinGenLHFPL2
Clinical trials, drugs, therapy
MyCancerGenomeLHFPL2
Protein Interactions : CTDLHFPL2
Pharm GKB GenePA30360
PharosQ6ZUX7
Clinical trialLHFPL2
Miscellaneous
canSAR (ICR)LHFPL2
HarmonizomeLHFPL2
DataMed IndexLHFPL2
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLHFPL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:15:52 CEST 2021

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