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LHFPL3 (lipoma HMGIC fusion partner-like 3)

Identity

Alias_namesLHFPL4
lipoma HMGIC fusion partner-like 4
Other alias
HGNC (Hugo) LHFPL3
LocusID (NCBI) 375612
Atlas_Id 54424
Location 7q22.2  [Link to chromosome band 7q22]
Location_base_pair Starts at 103969104 and ends at 104549003 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KMT2E (7q22.3) / LHFPL3 (7q22.2)LHFPL3 (7q22.2) / EEA1 (12q22)LHFPL3 (7q22.2) / KMT2B (19q13.12)
RPL8 (8q24.3) / LHFPL3 (7q22.2)LHFPL3 7q22.2 / EEA1 12q22MLL5 LHFPL3 7q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LHFPL3   6589
Cards
Entrez_Gene (NCBI)LHFPL3  375612  lipoma HMGIC fusion partner-like 3
AliasesLHFPL4
GeneCards (Weizmann)LHFPL3
Ensembl hg19 (Hinxton)ENSG00000187416 [Gene_View]  chr7:103969104-104549003 [Contig_View]  LHFPL3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000187416 [Gene_View]  chr7:103969104-104549003 [Contig_View]  LHFPL3 [Vega]
ICGC DataPortalENSG00000187416
TCGA cBioPortalLHFPL3
AceView (NCBI)LHFPL3
Genatlas (Paris)LHFPL3
WikiGenes375612
SOURCE (Princeton)LHFPL3
Genetics Home Reference (NIH)LHFPL3
Genomic and cartography
GoldenPath hg19 (UCSC)LHFPL3  -     chr7:103969104-104549003 +  7q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LHFPL3  -     7q22.2   [Description]    (hg38-Dec_2013)
EnsemblLHFPL3 - 7q22.2 [CytoView hg19]  LHFPL3 - 7q22.2 [CytoView hg38]
Mapping of homologs : NCBILHFPL3 [Mapview hg19]  LHFPL3 [Mapview hg38]
OMIM609719   
Gene and transcription
Genbank (Entrez)AK124251 AK299759 AW296968 AY260763 BC129937
RefSeq transcript (Entrez)NM_199000
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007933 NW_004929332
Consensus coding sequences : CCDS (NCBI)LHFPL3
Cluster EST : UnigeneHs.659164 [ NCBI ]
CGAP (NCI)Hs.659164
Alternative Splicing GalleryENSG00000187416
Gene ExpressionLHFPL3 [ NCBI-GEO ]   LHFPL3 [ EBI - ARRAY_EXPRESS ]   LHFPL3 [ SEEK ]   LHFPL3 [ MEM ]
Gene Expression Viewer (FireBrowse)LHFPL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)375612
GTEX Portal (Tissue expression)LHFPL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UP9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UP9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UP9
Splice isoforms : SwissVarQ86UP9
PhosPhoSitePlusQ86UP9
Domains : Interpro (EBI)Lipome_HGMIC_fus_partner-like   
Domain families : Pfam (Sanger)L_HGMIC_fpl (PF10242)   
Domain families : Pfam (NCBI)pfam10242   
Conserved Domain (NCBI)LHFPL3
DMDM Disease mutations375612
Blocks (Seattle)LHFPL3
SuperfamilyQ86UP9
Human Protein AtlasENSG00000187416
Peptide AtlasQ86UP9
HPRD17273
IPIIPI00902505   IPI00924533   
Protein Interaction databases
DIP (DOE-UCLA)Q86UP9
IntAct (EBI)Q86UP9
FunCoupENSG00000187416
BioGRIDLHFPL3
STRING (EMBL)LHFPL3
ZODIACLHFPL3
Ontologies - Pathways
QuickGOQ86UP9
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkLHFPL3
Atlas of Cancer Signalling NetworkLHFPL3
Wikipedia pathwaysLHFPL3
Orthology - Evolution
OrthoDB375612
GeneTree (enSembl)ENSG00000187416
Phylogenetic Trees/Animal Genes : TreeFamLHFPL3
HOVERGENQ86UP9
HOGENOMQ86UP9
Homologs : HomoloGeneLHFPL3
Homology/Alignments : Family Browser (UCSC)LHFPL3
Gene fusions - Rearrangements
Fusion : MitelmanKMT2E/LHFPL3 [7q22.3/7q22.2]  [t(7;7)(q22;q22)]  
Fusion : MitelmanLHFPL3/EEA1 [7q22.2/12q22]  [t(7;12)(q22;q22)]  
Fusion: TCGALHFPL3 7q22.2 EEA1 12q22 LGG
Fusion: TCGAMLL5 LHFPL3 7q22.2 BRCA LUAD OV SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLHFPL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LHFPL3
dbVarLHFPL3
ClinVarLHFPL3
1000_GenomesLHFPL3 
Exome Variant ServerLHFPL3
ExAC (Exome Aggregation Consortium)LHFPL3 (select the gene name)
Genetic variants : HAPMAP375612
Genomic Variants (DGV)LHFPL3 [DGVbeta]
DECIPHER (Syndromes)7:103969104-104549003  ENSG00000187416
CONAN: Copy Number AnalysisLHFPL3 
Mutations
ICGC Data PortalLHFPL3 
TCGA Data PortalLHFPL3 
Broad Tumor PortalLHFPL3
OASIS PortalLHFPL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLHFPL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLHFPL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LHFPL3
DgiDB (Drug Gene Interaction Database)LHFPL3
DoCM (Curated mutations)LHFPL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LHFPL3 (select a term)
intoGenLHFPL3
Cancer3DLHFPL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609719   
Orphanet
MedgenLHFPL3
Genetic Testing Registry LHFPL3
NextProtQ86UP9 [Medical]
TSGene375612
GENETestsLHFPL3
Huge Navigator LHFPL3 [HugePedia]
snp3D : Map Gene to Disease375612
BioCentury BCIQLHFPL3
ClinGenLHFPL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD375612
Chemical/Pharm GKB GenePA30361
Clinical trialLHFPL3
Miscellaneous
canSAR (ICR)LHFPL3 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLHFPL3
EVEXLHFPL3
GoPubMedLHFPL3
iHOPLHFPL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:06:59 CEST 2017

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