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LHFPL3 (LHFPL tetraspan subfamily member 3)

Identity

Alias (NCBI)LHFPL4
HGNC (Hugo) LHFPL3
HGNC Previous nameLHFPL4
HGNC Previous namelipoma HMGIC fusion partner-like 4
 lipoma HMGIC fusion partner-like 3
LocusID (NCBI) 375612
Atlas_Id 54424
Location 7q22.2  [Link to chromosome band 7q22]
Location_base_pair Starts at 104328656 and ends at 104908556 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KMT2E (7q22.3) / LHFPL3 (7q22.2)LHFPL3 (7q22.2) / EEA1 (12q22)LHFPL3 (7q22.2) / KMT2B (19q13.12)
RPL8 (8q24.3) / LHFPL3 (7q22.2)LHFPL3 7q22.2 / EEA1 12q22MLL5 LHFPL3 7q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LHFPL3   6589
Cards
Entrez_Gene (NCBI)LHFPL3    LHFPL tetraspan subfamily member 3
AliasesLHFPL4
GeneCards (Weizmann)LHFPL3
Ensembl hg19 (Hinxton)ENSG00000187416 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187416 [Gene_View]  ENSG00000187416 [Sequence]  chr7:104328656-104908556 [Contig_View]  LHFPL3 [Vega]
ICGC DataPortalENSG00000187416
TCGA cBioPortalLHFPL3
AceView (NCBI)LHFPL3
Genatlas (Paris)LHFPL3
SOURCE (Princeton)LHFPL3
Genetics Home Reference (NIH)LHFPL3
Genomic and cartography
GoldenPath hg38 (UCSC)LHFPL3  -     chr7:104328656-104908556 +  7q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LHFPL3  -     7q22.2   [Description]    (hg19-Feb_2009)
GoldenPathLHFPL3 - 7q22.2 [CytoView hg19]  LHFPL3 - 7q22.2 [CytoView hg38]
ImmunoBaseENSG00000187416
Genome Data Viewer NCBILHFPL3 [Mapview hg19]  
OMIM609719   
Gene and transcription
Genbank (Entrez)AK124251 AK299759 AW296968 AY260763 BC129937
RefSeq transcript (Entrez)NM_001386065 NM_199000
Consensus coding sequences : CCDS (NCBI)LHFPL3
Gene ExpressionLHFPL3 [ NCBI-GEO ]   LHFPL3 [ EBI - ARRAY_EXPRESS ]   LHFPL3 [ SEEK ]   LHFPL3 [ MEM ]
Gene Expression Viewer (FireBrowse)LHFPL3 [ Firebrowse - Broad ]
GenevisibleExpression of LHFPL3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)375612
GTEX Portal (Tissue expression)LHFPL3
Human Protein AtlasENSG00000187416-LHFPL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UP9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UP9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UP9
PhosPhoSitePlusQ86UP9
Domains : Interpro (EBI)LHFPL   
Domain families : Pfam (Sanger)L_HMGIC_fpl (PF10242)   
Domain families : Pfam (NCBI)pfam10242   
Conserved Domain (NCBI)LHFPL3
SuperfamilyQ86UP9
AlphaFold pdb e-kbQ86UP9   
Human Protein Atlas [tissue]ENSG00000187416-LHFPL3 [tissue]
HPRD17273
Protein Interaction databases
DIP (DOE-UCLA)Q86UP9
IntAct (EBI)Q86UP9
BioGRIDLHFPL3
STRING (EMBL)LHFPL3
ZODIACLHFPL3
Ontologies - Pathways
QuickGOQ86UP9
Ontology : AmiGOprotein binding  plasma membrane  sensory perception of sound  membrane  integral component of membrane  
Ontology : EGO-EBIprotein binding  plasma membrane  sensory perception of sound  membrane  integral component of membrane  
NDEx NetworkLHFPL3
Atlas of Cancer Signalling NetworkLHFPL3
Wikipedia pathwaysLHFPL3
Orthology - Evolution
OrthoDB375612
GeneTree (enSembl)ENSG00000187416
Phylogenetic Trees/Animal Genes : TreeFamLHFPL3
Homologs : HomoloGeneLHFPL3
Homology/Alignments : Family Browser (UCSC)LHFPL3
Gene fusions - Rearrangements
Fusion : MitelmanKMT2E/LHFPL3 [7q22.3/7q22.2]  
Fusion : MitelmanLHFPL3/EEA1 [7q22.2/12q22]  
Fusion : QuiverLHFPL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLHFPL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LHFPL3
dbVarLHFPL3
ClinVarLHFPL3
MonarchLHFPL3
1000_GenomesLHFPL3 
Exome Variant ServerLHFPL3
GNOMAD BrowserENSG00000187416
Varsome BrowserLHFPL3
ACMGLHFPL3 variants
VarityQ86UP9
Genomic Variants (DGV)LHFPL3 [DGVbeta]
DECIPHERLHFPL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLHFPL3 
Mutations
ICGC Data PortalLHFPL3 
TCGA Data PortalLHFPL3 
Broad Tumor PortalLHFPL3
OASIS PortalLHFPL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLHFPL3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLHFPL3
Mutations and Diseases : HGMDLHFPL3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLHFPL3
DgiDB (Drug Gene Interaction Database)LHFPL3
DoCM (Curated mutations)LHFPL3
CIViC (Clinical Interpretations of Variants in Cancer)LHFPL3
Cancer3DLHFPL3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609719   
Orphanet
DisGeNETLHFPL3
MedgenLHFPL3
Genetic Testing Registry LHFPL3
NextProtQ86UP9 [Medical]
GENETestsLHFPL3
Target ValidationLHFPL3
Huge Navigator LHFPL3 [HugePedia]
ClinGenLHFPL3
Clinical trials, drugs, therapy
MyCancerGenomeLHFPL3
Protein Interactions : CTDLHFPL3
Pharm GKB GenePA30361
PharosQ86UP9
Clinical trialLHFPL3
Miscellaneous
canSAR (ICR)LHFPL3
HarmonizomeLHFPL3
DataMed IndexLHFPL3
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLHFPL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:15:52 CEST 2021

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