Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LHX5 (LIM homeobox 5)

Identity

Other alias-
HGNC (Hugo) LHX5
LocusID (NCBI) 64211
Atlas_Id 56041
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 113462889 and ends at 113472072 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LHX5   14216
Cards
Entrez_Gene (NCBI)LHX5  64211  LIM homeobox 5
Aliases
GeneCards (Weizmann)LHX5
Ensembl hg19 (Hinxton)ENSG00000089116 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089116 [Gene_View]  chr12:113462889-113472072 [Contig_View]  LHX5 [Vega]
ICGC DataPortalENSG00000089116
TCGA cBioPortalLHX5
AceView (NCBI)LHX5
Genatlas (Paris)LHX5
WikiGenes64211
SOURCE (Princeton)LHX5
Genetics Home Reference (NIH)LHX5
Genomic and cartography
GoldenPath hg38 (UCSC)LHX5  -     chr12:113462889-113472072 -  12q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LHX5  -     12q24.13   [Description]    (hg19-Feb_2009)
EnsemblLHX5 - 12q24.13 [CytoView hg19]  LHX5 - 12q24.13 [CytoView hg38]
Mapping of homologs : NCBILHX5 [Mapview hg19]  LHX5 [Mapview hg38]
OMIM605992   
Gene and transcription
Genbank (Entrez)AF291181 BC109230
RefSeq transcript (Entrez)NM_022363
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LHX5
Cluster EST : UnigeneHs.302029 [ NCBI ]
CGAP (NCI)Hs.302029
Alternative Splicing GalleryENSG00000089116
Gene ExpressionLHX5 [ NCBI-GEO ]   LHX5 [ EBI - ARRAY_EXPRESS ]   LHX5 [ SEEK ]   LHX5 [ MEM ]
Gene Expression Viewer (FireBrowse)LHX5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64211
GTEX Portal (Tissue expression)LHX5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2C1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2C1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2C1
Splice isoforms : SwissVarQ9H2C1
PhosPhoSitePlusQ9H2C1
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Znf_LIM   
Domain families : Pfam (Sanger)Homeobox (PF00046)    LIM (PF00412)   
Domain families : Pfam (NCBI)pfam00046    pfam00412   
Domain families : Smart (EMBL)HOX (SM00389)  LIM (SM00132)  
Conserved Domain (NCBI)LHX5
DMDM Disease mutations64211
Blocks (Seattle)LHX5
SuperfamilyQ9H2C1
Human Protein AtlasENSG00000089116
Peptide AtlasQ9H2C1
HPRD09344
IPIIPI00022760   
Protein Interaction databases
DIP (DOE-UCLA)Q9H2C1
IntAct (EBI)Q9H2C1
FunCoupENSG00000089116
BioGRIDLHX5
STRING (EMBL)LHX5
ZODIACLHX5
Ontologies - Pathways
QuickGOQ9H2C1
Ontology : AmiGOnucleus  transcription, DNA-templated  zinc ion binding  spinal cord association neuron differentiation  cerebellar Purkinje cell differentiation  hippocampus development  cell proliferation in forebrain  forebrain neuron differentiation  cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  
Ontology : EGO-EBInucleus  transcription, DNA-templated  zinc ion binding  spinal cord association neuron differentiation  cerebellar Purkinje cell differentiation  hippocampus development  cell proliferation in forebrain  forebrain neuron differentiation  cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  
NDEx NetworkLHX5
Atlas of Cancer Signalling NetworkLHX5
Wikipedia pathwaysLHX5
Orthology - Evolution
OrthoDB64211
GeneTree (enSembl)ENSG00000089116
Phylogenetic Trees/Animal Genes : TreeFamLHX5
HOVERGENQ9H2C1
HOGENOMQ9H2C1
Homologs : HomoloGeneLHX5
Homology/Alignments : Family Browser (UCSC)LHX5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLHX5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LHX5
dbVarLHX5
ClinVarLHX5
1000_GenomesLHX5 
Exome Variant ServerLHX5
ExAC (Exome Aggregation Consortium)LHX5 (select the gene name)
Genetic variants : HAPMAP64211
Genomic Variants (DGV)LHX5 [DGVbeta]
DECIPHERLHX5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLHX5 
Mutations
ICGC Data PortalLHX5 
TCGA Data PortalLHX5 
Broad Tumor PortalLHX5
OASIS PortalLHX5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLHX5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLHX5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LHX5
DgiDB (Drug Gene Interaction Database)LHX5
DoCM (Curated mutations)LHX5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LHX5 (select a term)
intoGenLHX5
Cancer3DLHX5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605992   
Orphanet
MedgenLHX5
Genetic Testing Registry LHX5
NextProtQ9H2C1 [Medical]
TSGene64211
GENETestsLHX5
Huge Navigator LHX5 [HugePedia]
snp3D : Map Gene to Disease64211
BioCentury BCIQLHX5
ClinGenLHX5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64211
Chemical/Pharm GKB GenePA30367
Clinical trialLHX5
Miscellaneous
canSAR (ICR)LHX5 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLHX5
EVEXLHX5
GoPubMedLHX5
iHOPLHX5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:22:28 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.