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LHX6 (LIM homeobox 6)

Identity

Alias_symbol (synonym)LHX6.1
Other alias
HGNC (Hugo) LHX6
LocusID (NCBI) 26468
Atlas_Id 46414
Location 9q33.2  [Link to chromosome band 9q33]
Location_base_pair Starts at 122202577 and ends at 122228428 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LHX6 (9q33.2) / SYTL4 (Xq22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LHX6   21735
Cards
Entrez_Gene (NCBI)LHX6  26468  LIM homeobox 6
AliasesLHX6.1
GeneCards (Weizmann)LHX6
Ensembl hg19 (Hinxton)ENSG00000106852 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106852 [Gene_View]  chr9:122202577-122228428 [Contig_View]  LHX6 [Vega]
ICGC DataPortalENSG00000106852
TCGA cBioPortalLHX6
AceView (NCBI)LHX6
Genatlas (Paris)LHX6
WikiGenes26468
SOURCE (Princeton)LHX6
Genetics Home Reference (NIH)LHX6
Genomic and cartography
GoldenPath hg38 (UCSC)LHX6  -     chr9:122202577-122228428 -  9q33.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LHX6  -     9q33.2   [Description]    (hg19-Feb_2009)
EnsemblLHX6 - 9q33.2 [CytoView hg19]  LHX6 - 9q33.2 [CytoView hg38]
Mapping of homologs : NCBILHX6 [Mapview hg19]  LHX6 [Mapview hg38]
OMIM608215   
Gene and transcription
Genbank (Entrez)AB031041 AB031042 AI265821 AK126982 AK289827
RefSeq transcript (Entrez)NM_001242333 NM_001242334 NM_001242335 NM_001348190 NM_014368 NM_199160
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LHX6
Cluster EST : UnigeneHs.103137 [ NCBI ]
CGAP (NCI)Hs.103137
Alternative Splicing GalleryENSG00000106852
Gene ExpressionLHX6 [ NCBI-GEO ]   LHX6 [ EBI - ARRAY_EXPRESS ]   LHX6 [ SEEK ]   LHX6 [ MEM ]
Gene Expression Viewer (FireBrowse)LHX6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26468
GTEX Portal (Tissue expression)LHX6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPM6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPM6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPM6
Splice isoforms : SwissVarQ9UPM6
PhosPhoSitePlusQ9UPM6
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Znf_LIM   
Domain families : Pfam (Sanger)Homeobox (PF00046)    LIM (PF00412)   
Domain families : Pfam (NCBI)pfam00046    pfam00412   
Domain families : Smart (EMBL)HOX (SM00389)  LIM (SM00132)  
Conserved Domain (NCBI)LHX6
DMDM Disease mutations26468
Blocks (Seattle)LHX6
SuperfamilyQ9UPM6
Human Protein AtlasENSG00000106852
Peptide AtlasQ9UPM6
HPRD10498
IPIIPI00294419   IPI00853518   IPI00513787   IPI00852614   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPM6
IntAct (EBI)Q9UPM6
FunCoupENSG00000106852
BioGRIDLHX6
STRING (EMBL)LHX6
ZODIACLHX6
Ontologies - Pathways
QuickGOQ9UPM6
Ontology : AmiGOtranscription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  zinc ion binding  cerebral cortex radially oriented cell migration  cerebral cortex tangential migration  cerebral cortex GABAergic interneuron migration  sequence-specific DNA binding  cell maturation  
Ontology : EGO-EBItranscription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  zinc ion binding  cerebral cortex radially oriented cell migration  cerebral cortex tangential migration  cerebral cortex GABAergic interneuron migration  sequence-specific DNA binding  cell maturation  
NDEx NetworkLHX6
Atlas of Cancer Signalling NetworkLHX6
Wikipedia pathwaysLHX6
Orthology - Evolution
OrthoDB26468
GeneTree (enSembl)ENSG00000106852
Phylogenetic Trees/Animal Genes : TreeFamLHX6
HOVERGENQ9UPM6
HOGENOMQ9UPM6
Homologs : HomoloGeneLHX6
Homology/Alignments : Family Browser (UCSC)LHX6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLHX6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LHX6
dbVarLHX6
ClinVarLHX6
1000_GenomesLHX6 
Exome Variant ServerLHX6
ExAC (Exome Aggregation Consortium)LHX6 (select the gene name)
Genetic variants : HAPMAP26468
Genomic Variants (DGV)LHX6 [DGVbeta]
DECIPHERLHX6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLHX6 
Mutations
ICGC Data PortalLHX6 
TCGA Data PortalLHX6 
Broad Tumor PortalLHX6
OASIS PortalLHX6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLHX6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLHX6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LHX6
DgiDB (Drug Gene Interaction Database)LHX6
DoCM (Curated mutations)LHX6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LHX6 (select a term)
intoGenLHX6
Cancer3DLHX6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608215   
Orphanet
MedgenLHX6
Genetic Testing Registry LHX6
NextProtQ9UPM6 [Medical]
TSGene26468
GENETestsLHX6
Target ValidationLHX6
Huge Navigator LHX6 [HugePedia]
snp3D : Map Gene to Disease26468
BioCentury BCIQLHX6
ClinGenLHX6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26468
Chemical/Pharm GKB GenePA134949308
Clinical trialLHX6
Miscellaneous
canSAR (ICR)LHX6 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLHX6
EVEXLHX6
GoPubMedLHX6
iHOPLHX6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:05:15 CEST 2017

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