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LHX8 (LIM homeobox 8)

Identity

Alias_symbol (synonym)Lhx7
Other aliasLHX7
HGNC (Hugo) LHX8
LocusID (NCBI) 431707
Atlas_Id 65257
Location 1p31.1  [Link to chromosome band 1p31]
Location_base_pair Starts at 75128434 and ends at 75161533 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LHX8   28838
Cards
Entrez_Gene (NCBI)LHX8  431707  LIM homeobox 8
AliasesLHX7
GeneCards (Weizmann)LHX8
Ensembl hg19 (Hinxton)ENSG00000162624 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162624 [Gene_View]  chr1:75128434-75161533 [Contig_View]  LHX8 [Vega]
ICGC DataPortalENSG00000162624
TCGA cBioPortalLHX8
AceView (NCBI)LHX8
Genatlas (Paris)LHX8
WikiGenes431707
SOURCE (Princeton)LHX8
Genetics Home Reference (NIH)LHX8
Genomic and cartography
GoldenPath hg38 (UCSC)LHX8  -     chr1:75128434-75161533 +  1p31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LHX8  -     1p31.1   [Description]    (hg19-Feb_2009)
EnsemblLHX8 - 1p31.1 [CytoView hg19]  LHX8 - 1p31.1 [CytoView hg38]
Mapping of homologs : NCBILHX8 [Mapview hg19]  LHX8 [Mapview hg38]
OMIM604425   
Gene and transcription
Genbank (Entrez)AK094667 BC036423 BC040321 HQ447486
RefSeq transcript (Entrez)NM_001001933 NM_001256114
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LHX8
Cluster EST : UnigeneHs.403934 [ NCBI ]
CGAP (NCI)Hs.403934
Alternative Splicing GalleryENSG00000162624
Gene ExpressionLHX8 [ NCBI-GEO ]   LHX8 [ EBI - ARRAY_EXPRESS ]   LHX8 [ SEEK ]   LHX8 [ MEM ]
Gene Expression Viewer (FireBrowse)LHX8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)431707
GTEX Portal (Tissue expression)LHX8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68G74   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ68G74  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ68G74
Splice isoforms : SwissVarQ68G74
PhosPhoSitePlusQ68G74
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Znf_LIM   
Domain families : Pfam (Sanger)Homeobox (PF00046)    LIM (PF00412)   
Domain families : Pfam (NCBI)pfam00046    pfam00412   
Domain families : Smart (EMBL)HOX (SM00389)  LIM (SM00132)  
Conserved Domain (NCBI)LHX8
DMDM Disease mutations431707
Blocks (Seattle)LHX8
SuperfamilyQ68G74
Human Protein AtlasENSG00000162624
Peptide AtlasQ68G74
HPRD17275
IPIIPI00470355   IPI00480117   
Protein Interaction databases
DIP (DOE-UCLA)Q68G74
IntAct (EBI)Q68G74
FunCoupENSG00000162624
BioGRIDLHX8
STRING (EMBL)LHX8
ZODIACLHX8
Ontologies - Pathways
QuickGOQ68G74
Ontology : AmiGOfemale germ cell nucleus  protein binding  transcription, DNA-templated  regulation of transcription, DNA-templated  learning or memory  zinc ion binding  female gonad development  forebrain neuron development  odontogenesis of dentin-containing tooth  sequence-specific DNA binding  
Ontology : EGO-EBIfemale germ cell nucleus  protein binding  transcription, DNA-templated  regulation of transcription, DNA-templated  learning or memory  zinc ion binding  female gonad development  forebrain neuron development  odontogenesis of dentin-containing tooth  sequence-specific DNA binding  
NDEx NetworkLHX8
Atlas of Cancer Signalling NetworkLHX8
Wikipedia pathwaysLHX8
Orthology - Evolution
OrthoDB431707
GeneTree (enSembl)ENSG00000162624
Phylogenetic Trees/Animal Genes : TreeFamLHX8
HOVERGENQ68G74
HOGENOMQ68G74
Homologs : HomoloGeneLHX8
Homology/Alignments : Family Browser (UCSC)LHX8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLHX8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LHX8
dbVarLHX8
ClinVarLHX8
1000_GenomesLHX8 
Exome Variant ServerLHX8
ExAC (Exome Aggregation Consortium)LHX8 (select the gene name)
Genetic variants : HAPMAP431707
Genomic Variants (DGV)LHX8 [DGVbeta]
DECIPHERLHX8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLHX8 
Mutations
ICGC Data PortalLHX8 
TCGA Data PortalLHX8 
Broad Tumor PortalLHX8
OASIS PortalLHX8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLHX8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLHX8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LHX8
DgiDB (Drug Gene Interaction Database)LHX8
DoCM (Curated mutations)LHX8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LHX8 (select a term)
intoGenLHX8
Cancer3DLHX8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604425   
Orphanet
MedgenLHX8
Genetic Testing Registry LHX8
NextProtQ68G74 [Medical]
TSGene431707
GENETestsLHX8
Target ValidationLHX8
Huge Navigator LHX8 [HugePedia]
snp3D : Map Gene to Disease431707
BioCentury BCIQLHX8
ClinGenLHX8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD431707
Chemical/Pharm GKB GenePA142671553
Clinical trialLHX8
Miscellaneous
canSAR (ICR)LHX8 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLHX8
EVEXLHX8
GoPubMedLHX8
iHOPLHX8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:12:41 CEST 2017

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