Atlas of Genetics and Cytogenetics in Oncology and Haematology


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LILRB4 (leukocyte immunoglobulin like receptor B4)

Identity

Alias_namesleukocyte immunoglobulin-like receptor
Alias_symbol (synonym)LIR-5
ILT3
HM18
LIR5
CD85k
Other aliasCD85K
ILT-3
HGNC (Hugo) LILRB4
LocusID (NCBI) 11006
Atlas_Id 47591
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 54662819 and ends at 54670359 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LILRB4 (19q13.42) / IMPA2 (18p11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LILRB4   6608
Cards
Entrez_Gene (NCBI)LILRB4  11006  leukocyte immunoglobulin like receptor B4
AliasesCD85K; ILT-3; ILT3; LIR-5; 
LIR5
GeneCards (Weizmann)LILRB4
Ensembl hg19 (Hinxton)ENSG00000186818 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186818 [Gene_View]  chr19:54662819-54670359 [Contig_View]  LILRB4 [Vega]
ICGC DataPortalENSG00000186818
TCGA cBioPortalLILRB4
AceView (NCBI)LILRB4
Genatlas (Paris)LILRB4
WikiGenes11006
SOURCE (Princeton)LILRB4
Genetics Home Reference (NIH)LILRB4
Genomic and cartography
GoldenPath hg38 (UCSC)LILRB4  -     chr19:54662819-54670359 +  19q13.42   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LILRB4  -     19q13.42   [Description]    (hg19-Feb_2009)
EnsemblLILRB4 - 19q13.42 [CytoView hg19]  LILRB4 - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBILILRB4 [Mapview hg19]  LILRB4 [Mapview hg38]
OMIM604821   
Gene and transcription
Genbank (Entrez)AF025532 AF283988 AK292082 AK309227 AK314783
RefSeq transcript (Entrez)NM_001081438 NM_001278426 NM_001278427 NM_001278428 NM_001278429 NM_001278430 NM_006847
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_187693 NW_003571054 NW_003571060 NW_003571061
Consensus coding sequences : CCDS (NCBI)LILRB4
Cluster EST : UnigeneHs.731841 [ NCBI ]
CGAP (NCI)Hs.731841
Alternative Splicing GalleryENSG00000186818
Gene ExpressionLILRB4 [ NCBI-GEO ]   LILRB4 [ EBI - ARRAY_EXPRESS ]   LILRB4 [ SEEK ]   LILRB4 [ MEM ]
Gene Expression Viewer (FireBrowse)LILRB4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11006
GTEX Portal (Tissue expression)LILRB4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NHJ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NHJ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NHJ6
Splice isoforms : SwissVarQ8NHJ6
PhosPhoSitePlusQ8NHJ6
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)    Ig_2 (PF13895)   
Domain families : Pfam (NCBI)pfam00047    pfam13895   
Conserved Domain (NCBI)LILRB4
DMDM Disease mutations11006
Blocks (Seattle)LILRB4
PDB (SRS)3P2T   
PDB (PDBSum)3P2T   
PDB (IMB)3P2T   
PDB (RSDB)3P2T   
Structural Biology KnowledgeBase3P2T   
SCOP (Structural Classification of Proteins)3P2T   
CATH (Classification of proteins structures)3P2T   
SuperfamilyQ8NHJ6
Human Protein AtlasENSG00000186818
Peptide AtlasQ8NHJ6
HPRD11996
IPIIPI00853324   IPI00830045   IPI00658038   IPI00657926   IPI00657965   IPI00876860   
Protein Interaction databases
DIP (DOE-UCLA)Q8NHJ6
IntAct (EBI)Q8NHJ6
FunCoupENSG00000186818
BioGRIDLILRB4
STRING (EMBL)LILRB4
ZODIACLILRB4
Ontologies - Pathways
QuickGOQ8NHJ6
Ontology : AmiGOadaptive immune response  antigen binding  receptor activity  protein binding  plasma membrane  signal transduction  integral component of membrane  positive regulation of regulatory T cell differentiation  negative regulation of osteoclast differentiation  negative regulation of T cell receptor signaling pathway  extracellular exosome  negative regulation of protein localization to nucleus  negative regulation of pri-miRNA transcription from RNA polymerase II promoter  
Ontology : EGO-EBIadaptive immune response  antigen binding  receptor activity  protein binding  plasma membrane  signal transduction  integral component of membrane  positive regulation of regulatory T cell differentiation  negative regulation of osteoclast differentiation  negative regulation of T cell receptor signaling pathway  extracellular exosome  negative regulation of protein localization to nucleus  negative regulation of pri-miRNA transcription from RNA polymerase II promoter  
Pathways : KEGGOsteoclast differentiation   
NDEx NetworkLILRB4
Atlas of Cancer Signalling NetworkLILRB4
Wikipedia pathwaysLILRB4
Orthology - Evolution
OrthoDB11006
GeneTree (enSembl)ENSG00000186818
Phylogenetic Trees/Animal Genes : TreeFamLILRB4
HOVERGENQ8NHJ6
HOGENOMQ8NHJ6
Homologs : HomoloGeneLILRB4
Homology/Alignments : Family Browser (UCSC)LILRB4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLILRB4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LILRB4
dbVarLILRB4
ClinVarLILRB4
1000_GenomesLILRB4 
Exome Variant ServerLILRB4
ExAC (Exome Aggregation Consortium)LILRB4 (select the gene name)
Genetic variants : HAPMAP11006
Genomic Variants (DGV)LILRB4 [DGVbeta]
DECIPHERLILRB4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLILRB4 
Mutations
ICGC Data PortalLILRB4 
TCGA Data PortalLILRB4 
Broad Tumor PortalLILRB4
OASIS PortalLILRB4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLILRB4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLILRB4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LILRB4
DgiDB (Drug Gene Interaction Database)LILRB4
DoCM (Curated mutations)LILRB4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LILRB4 (select a term)
intoGenLILRB4
Cancer3DLILRB4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604821   
Orphanet
MedgenLILRB4
Genetic Testing Registry LILRB4
NextProtQ8NHJ6 [Medical]
TSGene11006
GENETestsLILRB4
Huge Navigator LILRB4 [HugePedia]
snp3D : Map Gene to Disease11006
BioCentury BCIQLILRB4
ClinGenLILRB4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11006
Chemical/Pharm GKB GenePA30382
Clinical trialLILRB4
Miscellaneous
canSAR (ICR)LILRB4 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLILRB4
EVEXLILRB4
GoPubMedLILRB4
iHOPLILRB4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri May 19 12:22:31 CEST 2017

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