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LIN54 (lin-54 DREAM MuvB core complex component)

Identity

Alias_nameslin-54 homolog (C. elegans)
Alias_symbol (synonym)MIP120
DKFZp686L1814
JC8.6
CXCDC1
TCX1
Other alias
HGNC (Hugo) LIN54
LocusID (NCBI) 132660
Atlas_Id 65278
Location 4q21.22  [Link to chromosome band 4q21]
Location_base_pair Starts at 83845757 and ends at 83934094 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LIN54 (4q21.22) / GDE1 (16p12.3)NAGS (17q21.31) / LIN54 (4q21.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LIN54   25397
Cards
Entrez_Gene (NCBI)LIN54  132660  lin-54 DREAM MuvB core complex component
AliasesCXCDC1; JC8.6; MIP120
GeneCards (Weizmann)LIN54
Ensembl hg19 (Hinxton)ENSG00000189308 [Gene_View]  chr4:83845757-83934094 [Contig_View]  LIN54 [Vega]
Ensembl hg38 (Hinxton)ENSG00000189308 [Gene_View]  chr4:83845757-83934094 [Contig_View]  LIN54 [Vega]
ICGC DataPortalENSG00000189308
TCGA cBioPortalLIN54
AceView (NCBI)LIN54
Genatlas (Paris)LIN54
WikiGenes132660
SOURCE (Princeton)LIN54
Genetics Home Reference (NIH)LIN54
Genomic and cartography
GoldenPath hg19 (UCSC)LIN54  -     chr4:83845757-83934094 -  4q21.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LIN54  -     4q21.22   [Description]    (hg38-Dec_2013)
EnsemblLIN54 - 4q21.22 [CytoView hg19]  LIN54 - 4q21.22 [CytoView hg38]
Mapping of homologs : NCBILIN54 [Mapview hg19]  LIN54 [Mapview hg38]
OMIM613367   
Gene and transcription
Genbank (Entrez)AB111889 AI208524 AK292769 AK294256 AK299787
RefSeq transcript (Entrez)NM_001115007 NM_001115008 NM_001288996 NM_001288997 NM_194282
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)LIN54
Cluster EST : UnigeneHs.96952 [ NCBI ]
CGAP (NCI)Hs.96952
Alternative Splicing GalleryENSG00000189308
Gene ExpressionLIN54 [ NCBI-GEO ]   LIN54 [ EBI - ARRAY_EXPRESS ]   LIN54 [ SEEK ]   LIN54 [ MEM ]
Gene Expression Viewer (FireBrowse)LIN54 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)132660
GTEX Portal (Tissue expression)LIN54
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6MZP7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6MZP7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6MZP7
Splice isoforms : SwissVarQ6MZP7
PhosPhoSitePlusQ6MZP7
Domaine pattern : Prosite (Expaxy)CRC (PS51634)   
Domains : Interpro (EBI)CRC    Lin-54_fam   
Domain families : Pfam (Sanger)TCR (PF03638)   
Domain families : Pfam (NCBI)pfam03638   
Conserved Domain (NCBI)LIN54
DMDM Disease mutations132660
Blocks (Seattle)LIN54
SuperfamilyQ6MZP7
Human Protein AtlasENSG00000189308
Peptide AtlasQ6MZP7
HPRD13218
IPIIPI00789941   IPI00655989   IPI00889131   IPI00900329   IPI00655863   IPI00968018   
Protein Interaction databases
DIP (DOE-UCLA)Q6MZP7
IntAct (EBI)Q6MZP7
FunCoupENSG00000189308
BioGRIDLIN54
STRING (EMBL)LIN54
ZODIACLIN54
Ontologies - Pathways
QuickGOQ6MZP7
Ontology : AmiGOG2/M transition of mitotic cell cycle  mitotic cell cycle  DNA binding  protein binding  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of cell cycle  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  mitotic cell cycle  DNA binding  protein binding  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of cell cycle  
NDEx NetworkLIN54
Atlas of Cancer Signalling NetworkLIN54
Wikipedia pathwaysLIN54
Orthology - Evolution
OrthoDB132660
GeneTree (enSembl)ENSG00000189308
Phylogenetic Trees/Animal Genes : TreeFamLIN54
HOVERGENQ6MZP7
HOGENOMQ6MZP7
Homologs : HomoloGeneLIN54
Homology/Alignments : Family Browser (UCSC)LIN54
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLIN54 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LIN54
dbVarLIN54
ClinVarLIN54
1000_GenomesLIN54 
Exome Variant ServerLIN54
ExAC (Exome Aggregation Consortium)LIN54 (select the gene name)
Genetic variants : HAPMAP132660
Genomic Variants (DGV)LIN54 [DGVbeta]
DECIPHER (Syndromes)4:83845757-83934094  ENSG00000189308
CONAN: Copy Number AnalysisLIN54 
Mutations
ICGC Data PortalLIN54 
TCGA Data PortalLIN54 
Broad Tumor PortalLIN54
OASIS PortalLIN54 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLIN54  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLIN54
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LIN54
DgiDB (Drug Gene Interaction Database)LIN54
DoCM (Curated mutations)LIN54 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LIN54 (select a term)
intoGenLIN54
Cancer3DLIN54(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613367   
Orphanet
MedgenLIN54
Genetic Testing Registry LIN54
NextProtQ6MZP7 [Medical]
TSGene132660
GENETestsLIN54
Huge Navigator LIN54 [HugePedia]
snp3D : Map Gene to Disease132660
BioCentury BCIQLIN54
ClinGenLIN54
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD132660
Chemical/Pharm GKB GenePA162394056
Clinical trialLIN54
Miscellaneous
canSAR (ICR)LIN54 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLIN54
EVEXLIN54
GoPubMedLIN54
iHOPLIN54
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:11:06 CET 2017

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