Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LIN7B (lin-7 homolog B, crumbs cell polarity complex component)

Identity

Alias_nameslin-7 homolog B (C. elegans)
Alias_symbol (synonym)MALS-2
LIN-7B
VELI2
Other aliasMALS2
HGNC (Hugo) LIN7B
LocusID (NCBI) 64130
Atlas_Id 65280
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 49114361 and ends at 49118460 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LIN7B   17788
Cards
Entrez_Gene (NCBI)LIN7B  64130  lin-7 homolog B, crumbs cell polarity complex component
AliasesLIN-7B; MALS-2; MALS2; VELI2
GeneCards (Weizmann)LIN7B
Ensembl hg19 (Hinxton)ENSG00000104863 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104863 [Gene_View]  chr19:49114361-49118460 [Contig_View]  LIN7B [Vega]
ICGC DataPortalENSG00000104863
TCGA cBioPortalLIN7B
AceView (NCBI)LIN7B
Genatlas (Paris)LIN7B
WikiGenes64130
SOURCE (Princeton)LIN7B
Genetics Home Reference (NIH)LIN7B
Genomic and cartography
GoldenPath hg38 (UCSC)LIN7B  -     chr19:49114361-49118460 +  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LIN7B  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblLIN7B - 19q13.33 [CytoView hg19]  LIN7B - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBILIN7B [Mapview hg19]  LIN7B [Mapview hg38]
OMIM612331   
Gene and transcription
Genbank (Entrez)AF311862 AY358744 BC027618 BM069859
RefSeq transcript (Entrez)NM_001308419 NM_022165
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LIN7B
Cluster EST : UnigeneHs.221737 [ NCBI ]
CGAP (NCI)Hs.221737
Alternative Splicing GalleryENSG00000104863
Gene ExpressionLIN7B [ NCBI-GEO ]   LIN7B [ EBI - ARRAY_EXPRESS ]   LIN7B [ SEEK ]   LIN7B [ MEM ]
Gene Expression Viewer (FireBrowse)LIN7B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64130
GTEX Portal (Tissue expression)LIN7B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HAP6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HAP6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HAP6
Splice isoforms : SwissVarQ9HAP6
PhosPhoSitePlusQ9HAP6
Domaine pattern : Prosite (Expaxy)L27 (PS51022)    PDZ (PS50106)   
Domains : Interpro (EBI)L27_C    L27_dom    PDZ   
Domain families : Pfam (Sanger)L27 (PF02828)    PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam02828    pfam00595   
Domain families : Smart (EMBL)L27 (SM00569)  PDZ (SM00228)  
Conserved Domain (NCBI)LIN7B
DMDM Disease mutations64130
Blocks (Seattle)LIN7B
PDB (SRS)2DKR   
PDB (PDBSum)2DKR   
PDB (IMB)2DKR   
PDB (RSDB)2DKR   
Structural Biology KnowledgeBase2DKR   
SCOP (Structural Classification of Proteins)2DKR   
CATH (Classification of proteins structures)2DKR   
SuperfamilyQ9HAP6
Human Protein AtlasENSG00000104863
Peptide AtlasQ9HAP6
HPRD10040
IPIIPI00005566   IPI00792650   
Protein Interaction databases
DIP (DOE-UCLA)Q9HAP6
IntAct (EBI)Q9HAP6
FunCoupENSG00000104863
BioGRIDLIN7B
STRING (EMBL)LIN7B
ZODIACLIN7B
Ontologies - Pathways
QuickGOQ9HAP6
Ontology : AmiGOplasma membrane  cell-cell junction  bicellular tight junction  exocytosis  neurotransmitter secretion  neurotransmitter secretion  postsynaptic density  protein transport  basolateral plasma membrane  protein domain specific binding  PDZ domain binding  neuron projection  maintenance of epithelial cell apical/basal polarity  synapse  postsynaptic membrane  presynapse  protein localization to basolateral plasma membrane  
Ontology : EGO-EBIplasma membrane  cell-cell junction  bicellular tight junction  exocytosis  neurotransmitter secretion  neurotransmitter secretion  postsynaptic density  protein transport  basolateral plasma membrane  protein domain specific binding  PDZ domain binding  neuron projection  maintenance of epithelial cell apical/basal polarity  synapse  postsynaptic membrane  presynapse  protein localization to basolateral plasma membrane  
NDEx NetworkLIN7B
Atlas of Cancer Signalling NetworkLIN7B
Wikipedia pathwaysLIN7B
Orthology - Evolution
OrthoDB64130
GeneTree (enSembl)ENSG00000104863
Phylogenetic Trees/Animal Genes : TreeFamLIN7B
HOVERGENQ9HAP6
HOGENOMQ9HAP6
Homologs : HomoloGeneLIN7B
Homology/Alignments : Family Browser (UCSC)LIN7B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLIN7B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LIN7B
dbVarLIN7B
ClinVarLIN7B
1000_GenomesLIN7B 
Exome Variant ServerLIN7B
ExAC (Exome Aggregation Consortium)LIN7B (select the gene name)
Genetic variants : HAPMAP64130
Genomic Variants (DGV)LIN7B [DGVbeta]
DECIPHERLIN7B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLIN7B 
Mutations
ICGC Data PortalLIN7B 
TCGA Data PortalLIN7B 
Broad Tumor PortalLIN7B
OASIS PortalLIN7B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLIN7B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLIN7B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LIN7B
DgiDB (Drug Gene Interaction Database)LIN7B
DoCM (Curated mutations)LIN7B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LIN7B (select a term)
intoGenLIN7B
Cancer3DLIN7B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612331   
Orphanet
MedgenLIN7B
Genetic Testing Registry LIN7B
NextProtQ9HAP6 [Medical]
TSGene64130
GENETestsLIN7B
Target ValidationLIN7B
Huge Navigator LIN7B [HugePedia]
snp3D : Map Gene to Disease64130
BioCentury BCIQLIN7B
ClinGenLIN7B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64130
Chemical/Pharm GKB GenePA134914453
Clinical trialLIN7B
Miscellaneous
canSAR (ICR)LIN7B (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLIN7B
EVEXLIN7B
GoPubMedLIN7B
iHOPLIN7B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:12:44 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.